2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-127067
    Yuanhuadin 76402-66-9 98%
    Yuanhuadin, extracted from Genkwa Flos Daphne genkwa, has antitumor activity through inhibiting Akt/mTOR and EGFR pathways, induce cell-cycle arrest and abortion.
    Yuanhuadin
  • HY-127150
    Clofezone 17449-96-6 98%
    Clofezone (Perclusone) is an antirheumatic agent that inhibits collagen formation in rat Chondrus granulomas. Clofezone can be used in the study of various rheumatic diseases, especially arthritis (RA) and ankylosing spondylitis (AS).
    Clofezone
  • HY-12764R
    6-OAU (Standard) 83797-69-7
    Prochloraz manganese (Standard) is the analytical standard of Prochloraz manganese. This product is intended for research and analytical applications. Prochloraz manganese is an antifungal agent, and is used in agricultural industries.
    6-OAU (Standard)
  • HY-12767S
    4-Hydroxyphenyl Carvedilol-d5 1261395-96-3 98%
    4-Hydroxyphenyl Carvedilol-d5 is the deuterium labeled 4-Hydroxyphenyl Carvedilol.
    4-Hydroxyphenyl Carvedilol-d5
  • HY-128043
    11-Deoxy prostaglandin E1 37786-00-8 98%
    11-Deoxy prostaglandin E1 (AY-23578; Doproston B) is an analog of prostaglandin E1 (PGE1) with bronchodilator activity. 11-Deoxy prostaglandin E1 inhibits histamine-induced bronchoconstriction and causes relaxation of tracheal strips in isolated guinea pigs.
    11-Deoxy prostaglandin E1
  • HY-128135
    MHY 553 6265-56-1 98%
    MHY 553 is a PPARα agonist that is effective when taken orally. MHY 553 helps alleviate liver fat accumulation by increasing fatty acid oxidation and reducing inflammation during the aging process. MHY 553 inhibits the accumulation of triglycerides induced by liver X receptor agonists in HepG2 cells. MHY 553 significantly suppresses the expression of inflammatory mRNA in aging rats.
    MHY 553
  • HY-128231
    GRK6-IN-4 300731-73-1 98%
    GRK6-IN-4 is a G protein coupled receptor 6 kinase (GRK6) inhibitor with an IC50 of 1.56 μM. GRK6-IN-4 can be utilized in research related to hematological malignancies, inflammatory diseases, and autoimmune disorders.
    GRK6-IN-4
  • HY-128311
    GRK6-IN-3 499231-87-7 98%
    GRK6-IN-3 is a G protein coupled receptor 6 kinase (GRK6) inhibitor with an IC50 1.03 μM.
    GRK6-IN-3
  • HY-128361
    SLC26A3-IN-3 2369983-43-5 98%
    SLC26A3-IN-3 (compound 4az) is a SLC26A3 inhibitor (IC50: 40 nM). SLC26A3-IN-3 can be used for research of constipation, cystic fibrosis.
    SLC26A3-IN-3
  • HY-128418
    Benzonatate (PEGn) 32760-16-0 98%
    Benzonatate (PEGn) is a unique non-narcotic antitussive agent that has sodium channel-blocking properties and anesthetic effects on the respiratory stretch receptors.
    Benzonatate (PEGn)
  • HY-128449
    Cephradine monohydrate 75975-70-1
    Cephradine (Cefradine) monohydrate is a broad-spectrum and orally active cephalosporin. Cephradine monohydrate is active against both grampositive and gram-negative pathogens and effective in eradicating most penicillinase-producing organisms known to be resistant to penicillin G, penicillin V, and ampicillin. Cephradine monohydrate has been used in the research of genitourinary, gastrointestinal and respiratory tract infections, and in infections of the skin and soft tissues. Cephradine monohydrate blocks solar-ultraviolet induced skin inflammation through direct inhibition of TOPK.
    Cephradine monohydrate
  • HY-128450
    JAK-STAT-IN-1 1236666-76-4 98%
    JAK-STAT-IN-1 (compound 1) is a selective JAK-STAT inhibitor. JAK-STAT-IN-1 can be used for the research of autoimmune disorder.
    JAK-STAT-IN-1
  • HY-128452
    2'-​Hydroxy-​2-​methoxychalcone 42220-77-9 98%
    2'-Hydroxy-2-methoxychalcone (compound 3b) is a synthetic chalcone, with antimicrobial activity.
    2'-​Hydroxy-​2-​methoxychalcone
  • HY-128546
    Flupranone 21686-10-2 98%
    Flupranone is a pyrazole derivatives with antiinflammatory and antihypertensive properties.
    Flupranone
  • HY-12866B
    (R)-Larotrectinib 1223404-68-9 98%
    (R)-Larotrectinib is a potent TRK inhibitor with an IC50 value of 28.5 nM for TrkA. (R)-Larotrectinib can be used for researching cancer, inflammatory and certain infectious diseases
    (R)-Larotrectinib
  • HY-128695
    Oleanolic acid hemiphthalate disodium salt 168770-31-8 98.05%
    Oleanolic acid hemiphthalate disodium salt is a hemiphthalate derivative of Oleanolic acid (HY-128695) with anti-inflammatory and potential anti-ulcer activities.
    Oleanolic acid hemiphthalate disodium salt
  • HY-128934
    Antitumor agent-2 1351163-57-9 98%
    Antitumor agent-2 is sourced from patent CN102250203, compound 6a-r, has antitumor action and anti-inflammatory action.
    Antitumor agent-2
  • HY-129143
    Delphinidin-3-sambubioside chloride 53158-73-9 98%
    Delphinidin-3-sambubioside (Dp3‐Sam) chloride is an anthocyanin that has orally active anti-inflammatory activity. Delphinidin-3-sambubioside chloride inhibits LPS-induced inflammatory factors release. Delphinidin-3-sambubioside chloride also alleviates hepatic lipid accumulation in HFD rats. Delphinidin-3-sambubioside chloride can be isolated from Hibiscus sabdariffa L..
    Delphinidin-3-sambubioside chloride
  • HY-129214
    (2S,3R)-DEPMPO-Biotin 936224-52-1 98%
    (2S,3R)-DEPMPO-Biotin is a spin trapping agent consists of DEPMPO (HY-120976) and Biotin (HY-B0511). (2S,3R)-DEPMPO-Biotin captures macromolecule free radicals in lesions.
    (2S,3R)-DEPMPO-Biotin
  • HY-129311
    Tr-PEG6-OH 127999-16-0
    Tr-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
    Tr-PEG6-OH
Cat. No. Product Name / Synonyms Application Reactivity