1. Inflammation/Immunology

Inflammation/Immunology

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-121239
    Lemnalol 82570-34-1 98%
    Lemnalol is a potent agent for neuropathic pain. Lemnalol possesses potent anti-inflammatory, analgesic and anti-tumor activities. Lemnalol has the capacity to attenuate hyperalgesia and allodynia by modulation of neuroinflammatory processes in neuropathy. Lemnalol modulates LPS-induced alterations of left atrial (LA) calcium homeostasis and blocks the NF-κB pathways, which may contribute to the attenuation of lipopolysaccharide (LPS)-induced arrhythmogenesis and neuropathic pain. Lemnalolis a ylangene-type sesquiterpenoid compound, isolated from Lemnalia cervicorni.
    Lemnalol
  • HY-121272
    Difloxacin 98106-17-3 98%
    Difloxacin is an antimicrobial agent.
    Difloxacin
  • HY-121278
    Benzotript 39544-74-6 98%
    Benzotript (Benzotriptum) is a cholecystokinin-receptor (CCK) and gastrin receptor antagonist. Benzotript shows antiproliferative effects in human colon carcinoma cell lines.
    Benzotript
  • HY-121293
    CP-944629 668990-94-1 98%
    CP-944629 (Compound 20) is an inhibitor of p38 alpha kinase with an IC50 of 3.2. CP-944629 can be studied in research for chronic inflammation diseases.
    CP-944629
  • HY-121347
    Enterocin 59678-46-5 98%
    Enterocin, an antibiotic, has static activities against gram-positive and gram-negative bacteria and no activity against fungi and yeast.
    Enterocin
  • HY-121351
    Inokosterone 15130-85-5 98%
    Inokosterone is a potential agent target of estrogen receptor 1 in rheumatoid arthritis patients.
    Inokosterone
  • HY-121377
    Epiyangambin 24192-64-1 98%
    Epiyangambin is a competitive platelet activating factor receptor (PAF) antagonist that dose-dependently inhibits PAF-induced platelet aggregation. Epiyangambin also inhibits the growth of human colon cancer cells (SW480 cells).
    Epiyangambin
  • HY-121397
    Phyltetralin 123048-17-9 98%
    Phyltetralin (Compound 10) is a natural product than can be isolated from the hexane-ethyl acetate extract of Phyllanthus amarus leaves. Phyltetralin possesses immunosuppressive effects on different lineages of innate immune system.
    Phyltetralin
  • HY-121406
    (Z)-Lafutidine 206449-93-6 98%
    (Z)-Lafutidine ((Z)-FRG-8813) is a potent histamine H2 receptor antagonist. (Z)-Lafutidine shows anti-secretory and gastroprotective activities.
    (Z)-Lafutidine
  • HY-121421
    Diniprofylline 17692-30-7 98%
    Diniprofylline, a bronchodilator, is a phosphodiesterase inhibitor. Diniprofylline possesses the potential to interact with human ACE2 and prevent its recognition by SARS-CoV-2.
    Diniprofylline
  • HY-121431
    FR-901235 124190-19-8 98%
    FR-901235 is a new type of immunoactive substance produced by an imperfect fungus, Paecilomyces carneus F-4882. FR-901235 partially restored the impaired delayed-type hypersensitivity to sheep red blood cells in tumor-bearing mice.
    FR-901235
  • HY-121456
    Salnacedin 87573-01-1 98%
    Salnacedin (G-201) has anti-inflammatory and keratolytic activity. Salnacedin can be used in the research of seborrhoeic dermatitis and acne.
    Salnacedin
  • HY-121467
    Acotiamide 185106-16-5 99.92%
    Acotiamide is an orally active, selective and reversible acetylcholinesterase (AChE) inhibitor, with an IC50 of 1.79 μM. Acotiamide can enhance gastric contractility and accelerate delayed gastric emptying. Acotiamide has the potential for the research of functional dyspepsia involving gastric motility dysfunction and intestinal inflammatory.
    Acotiamide
  • HY-121481
    Cucurbitadienol 35012-08-9 98%
    Cucurbitadienol (10α-Cucurbitadienol) is a natural product that can be found in the seeds of Trichosanthes kirilowii. Cucurbitadienol exhibits anti-inflammatory effect.
    Cucurbitadienol
  • HY-121496
    3M-011 642473-62-9 98%
    3M-011 is a potent dual toll-like receptor TLR7/8 agonist and a cytokine inducer. 3M-011 significantly inhibits H3N2 influenza viral replication in the nasal cavity. 3M-011 is also a potent adjuvant to radiotherapy that induces local and profound systemic immune responses during radiotherapy. 3M-011 strongly has antitumor action.
    3M-011
  • HY-121545
    CB-52 869376-90-9 98%
    CB-52 is the ligand and neutral antagonist of CB2 cannabinoid receptor.
    CB-52
  • HY-121594
    GSK-269984B 892664-17-4 98%
    GSK-269984B is a potent EP1 antagonist. GSK-269984B has the potential for inflammatory pain research.
    GSK-269984B
  • HY-121611
    HI-236 233271-65-3 98%
    HI-236 is a potent non-nucleoside inhibitor of HIV-1 reverse transcriptase.? HI-236 inhibits HIV activity (wild type HTLVIIB IC50p24 < 0.001 μM).
    HI-236
  • HY-121621
    RO5101576 1123155-95-2 98%
    RO5101576 is a potent LTB4 receptor antagonist with activity to inhibit LTB4-induced calcium mobilization and chemotaxis of human neutrophils. RO5101576 significantly attenuated LTB4-induced pulmonary eosinophilia in guinea pigs. RO5101576 inhibited allergen- and ozone-induced pulmonary neutrophilia in nonhuman primates with efficacy comparable to that of budesonide. RO5101576 had no effect on LPS-induced neutrophilia in guinea pigs and cigarette smoke-induced neutrophilia in mice and rats. RO5101576 performed well in toxicology studies and was well tolerated.
    RO5101576
  • HY-121662
    Lenaldekar 418800-15-4 98%
    Lenaldekar (LDK) inhibits human and murine T-cell expansiomn. Lenaldekar inhibits autoimmune T cell response. Lenaldekar also induces cancer cell apoptosis. Lenaldekar can be used for T-cell mediated autoimmune diseases research.
    Lenaldekar
Cat. No. Product Name / Synonyms Application Reactivity