2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-116885
    Thunalbene 220862-05-5 98%
    Thunalbene is a stilbene derivative isolated from Thunia alba. Thunalbene has a weak inhibitory effect on nitric oxide production and is not cytotoxic.
    Thunalbene
  • HY-116890
    CRTh2 antagonist 4 916046-55-4 98%
    CRTh2 antagonist 4 (compound 58) is an inhibitor (IC50: 212 nM) of TH2 lymphocyte (CRTH2 or DP2) receptor with high binding affinity (Ki= 37 nM). CRTh2 antagonist 4 can be used in the study of severe allergic diseases.
    CRTh2 antagonist 4
  • HY-116933
    Murrayanol 144525-81-5 98%
    Murrayanol is a natural carbazole alkaloid with a variety of biological activities. Murrayanol shows anti-inflammatory, topoisomerase I and topoisomerase II (Topoisomerase) inhibition activities. Murrayanol also as a mosquitocidal and antimicrobial.
    Murrayanol
  • HY-116947
    COX-2-IN-5 416901-58-1 98%
    COX-2-IN-5 (compound 11a) is a potent COX-2 inhibitor with an IC50 value of 0.65 µM. COX-2-IN-5 has the potential for the research of inflammation.
    COX-2-IN-5
  • HY-117008
    CAY10589 1077626-52-8 98%
    CAY10589 is an inhibitor of mPGES-1, an enzyme induced during inflammatory responses. CAY10589 has no significant effect on the differentiation of BM myeloid precursor cells into M2-like TAMs.
    CAY10589
  • HY-117024
    Abediterol napadisylate 1044516-17-7 98%
    Abediterol napadisylate is an inhaled long-acting β2-adrenoceptor agonist (LABA) and can be used for the research of asthma and chronic obstructive pulmonary disease (COPD).
    Abediterol napadisylate
  • HY-117091
    DDD-028 1538586-09-2 98%
    DDD-028 is a potent non-opioid, non-cannabinoid analgesic which attenuates neuropathic and inflammatory pain without the possible side effects or abuse potential associated with opioid or cannabinoid activities. DDD-028 can be utilized in analgesic research.
    DDD-028
  • HY-117151
    A-315675 335679-69-1 98%
    A-315675 is a potent highly potent inhibitor of A and B strain influenza virus neuraminidases inhibitor.
    A-315675
  • HY-117182
    LG190178 233268-81-0 98%
    LG190178 is a non-steroidal vitamin D receptor (VDR) ligand that can induce the formation of heterodimer complexes between VDR and retinoid X receptor (RXR), stabilizing the agonistic conformation of the VDR ligand-binding domain and promoting its interaction with co-activators. LG190178 has functions in regulating calcium homeostasis, bone mineralization, as well as cell proliferation, differentiation, and apoptosis, making it useful for research in psoriasis, osteoporosis, and cancer.
    LG190178
  • HY-117256
    Gabazine free base 105538-73-6 98%
    Gabazine is a selective and competitive antagonist of GABAA receptor, with an IC50 of 0.2 μM for GABA receptor.
    Gabazine free base
  • HY-117378
    N-5984 220475-76-3 98%
    N-5984 (KRP-204) is a potent and selective agonist of β3-adrenergic receptor. N-5984 has the potential for developing as one of the clinically effective drugs for obesity and diabetes mellitus.
    N-5984
  • HY-117463
    Dexamethasone beloxil 150587-07-8 98%
    Dexamethasone beloxil (AL-2512) is a novel corticosteroid with anti-inflammatory and ocular hypertensive effects .
    Dexamethasone beloxil
  • HY-117500
    Aplysamine-1 159026-30-9 98%
    Aplysamine-1 acts as an antagonist for the histamine H3 receptor.
    Aplysamine-1
  • HY-117501
    Dexchlorpheniramine 25523-97-1 98%
    Dexchlorpheniramine is an potent and blood-brain barrier (BBB) penetrant histamine 1 (H1) receptor antagonist with anticholinergic properties. Dexchlorpheniramine can be used for researching allergies.
    Dexchlorpheniramine
  • HY-117514
    5-LOX-IN-7 1272519-89-7 98%
    5-LOX-IN-7 (compound 18) is a potent LOX inhibitor. 5-LOX-IN-7 has the potential for the research of inflammatory and allergic diseases and certain cancer.
    5-LOX-IN-7
  • HY-117518
    Paranyline 1729-61-9 98%
    Paranyline is a novel anti-inflammatory treatment specifically designed for arthritis.
    Paranyline
  • HY-117569
    KF24345 free base 178750-21-5 98%
    KF24345 free base is an orally active adenosine uptake inhibitor. KF24345 free base inhibits adenosine uptake by human, mouse, rabbit and hamster erythrocytes with IC50 values of 59.5, 130.1, 104.2 and 30.9 nM, respectively. KF24345 free base has anti-inflammatory activity and can inhibit LPS-induced TNF-α production and leukopenia in mice.
    KF24345 free base
  • HY-117601
    11-Deoxyalisol B 155073-73-7 98%
    11-Deoxyalisol B, a triterpene, shows the potent inhibitory activity on Lipopolysaccharide (LPS)-induced nitric oxide (NO) production.
    11-Deoxyalisol B
  • HY-117652
    Lobetyol 136171-87-4 98%
    Lobetyol is a natural compound that can be isolated from Lobelia chinensis. Lobetyol induces apoptosis and cell cycle arrest in MKN45 cells. Lobetyol shows anti-virus, anti-inflammation and anti-tumor activity. Lobetyol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Lobetyol
  • HY-117659
    PGDM 133161-96-3 98%
    PGDM (Prostaglandin D Metabolite) is the main urinary metabolite of Prostaglandin D2 and is prone to reversible cyclization. PGDM may serve as a biomarker for the endogenous production of PGD2 or be used to evaluate the severity of acute allergic reactions.
    PGDM
Cat. No. Product Name / Synonyms Application Reactivity