2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-107609
    BAY-u 9773 154978-38-8 98%
    BAY-u 9773 is a non-selective antagonist of the CysLT receptors (cysteinyl leukotrienes receptors) with about the same IC50 for CysLT1 and CysLT2. BAY-u9773 is used for the inhibition of LT responses.
    BAY-u 9773
  • HY-107611
    Ro 24-5913 128312-51-6 98%
    Ro 24-5913 (Cinalukast) is an orally active and potent LTD4 antagonist with an IC50 value of 6.4 nM. Ro 24-5913 can be used for the research of asthma.
    Ro 24-5913
  • HY-107666
    PHA 568487 527680-57-5 98%
    PHA 568487 a selective agonist of alpha-7 nicotinic acetylcholine receptor (α-7 nAchR).PHA 568487 reduces neuroinflammation and oxidative stress. PHA-568487 has rapid brain penetration.
    PHA 568487
  • HY-107710
    LY 233053 125546-04-5 98%
    LY 233053 is a potent and competitive NMDA-receptor antagonist with anticonvulsant and antiepileptic efficacy.
    LY 233053
  • HY-107736
    AI-3 882288-28-0 98%
    AI-3 is a potent ARE (antioxidant response element) activator. AI-3 increases the NQO1 at the transcript levels and protein expression levels. AI-3 has the potential for the research of oxidative stress related diseases.
    AI-3
  • HY-107787
    Dioxopromethazine 13754-56-8 98%
    Dioxopromethazine is an orally active antihistamine. Dioxopromethazine inhibits asthmatic symptoms.
    Dioxopromethazine
  • HY-107796
    Metamizole magnesium 63372-86-1 98%
    Metamizole magnesium is an orally active cyclooxygenase (COX) inhibitor. Metamizole magnesium can inhibit cell proliferation and promote cell apoptosis. Metamizole magnesium has anti-inflammatory and antioxidant activities. Metamizole magnesium is an antipyretic, analgesic and spasmolytic agent.
    Metamizole magnesium
  • HY-107949
    Flumethasone pivalate 2002-29-1 98.17%
    Flumethasone pivalate is a glucocorticoid corticosteroid and a corticosteroid ester. Flumetasone pivalate has anti-inflammatory, antipruritic, and vasoconstrictive activities.
    Flumethasone pivalate
  • HY-108030
    Bencycloquidium bromide 860804-18-8 98%
    Bencycloquidium bromide, a muscarinic M(3) receptor antagonist, is an anticholinergic compound that acts as an anticholinergic bronchodilator. Bencycloquidium bromide can be used in the study for rhinitis.
    Bencycloquidium bromide
  • HY-108040
    NCX-6560 803728-45-2 98%
    NCX-6560 is an orally active nitric oxide releasing derivative of atorvastatin that inhibits cholesterol biosynthesis and has anti-inflammatory and antithrombotic activity.
    NCX-6560
  • HY-108047
    MK-0873 500355-52-2 98%
    MK-0873 is a selective phosphodiesterase-4 (PDE4) inhibitor. MK-0873 increases intracellular levels of cyclic adenosine phosphate (cAMP) by inhibiting the activity of the PDE4 enzyme and subsequently activates protein kinase A (PKA). Activated PKA inhibits the activity of inflammatory cells and leads to direct relaxation of airway smooth muscle. MK-0873 can be used in studies of chronic obstructive pulmonary disease (COPD).
    MK-0873
  • HY-108050
    4-Hydroxyoxyphenbutazone 55648-39-0 98%
    4-Hydroxyoxyphenbutazone kills both replicating and nonreplicating (NR) Mycobacterium tuberculosis (Mtb), including Mtb resistant to standard agents. 4-Hydroxyoxyphenbutazone is a potent inhibitor of cytokine production. 4-Hydroxyoxyphenbutazone is an immunosuppressive agent and has the potential for rheumatoid arthritis research.
    4-Hydroxyoxyphenbutazone
  • HY-108132
    Ro 23-9358 153125-17-8 98%
    Ro 23-9358 is a potent secretory phospholipase A2 inhibitor with anti-inflammatory activity.
    Ro 23-9358
  • HY-108166
    Hydroxystilbamidine 495-99-8 98%
    Hydroxystilbamidine, a dye capable of binding to both DNA and RNA, is a powerful inhibitor of cellular ribonucleases. Hydroxystilbamidine is a retrograde fluorescent tracer and a histochemical stain[1]
    Hydroxystilbamidine
  • HY-108249
    Tribenoside 10310-32-4 98%
    Tribenoside is a vasoprotective agent, can be used for the research of hemorrhoids. Tribenoside has mild anti-inflammatory, analgesic, and wound healing properties.
    Tribenoside
  • HY-108280
    Tropesin 65189-78-8 98%
    Tropesin (VUFB 12018; Repanidal) is a nonsteroid antiinflammatory agent (NSAIA) that inhibits the growth of Trichoderma viride.
    Tropesin
  • HY-108281
    Enfenamic acid 23049-93-6 98%
    Enfenamic acid is a nonsteroidal anti-inflammatory agent and a prostaglandin synthetase inhibitor, inhibiting hepatic gluconeogenesis in Swiss albino mice. Enfenamic acid suppresses wound healing.
    Enfenamic acid
  • HY-108308
    Ibuprofen guaiacol ester 66332-77-2 98.49%
    Ibuprofen guaiacol ester (AF 2259; Metoxibutropate) is a potent and orally active prostaglandin synthesis inhibitor. Ibuprofen guaiacol ester has the potential for the research of edema and fever.
    Ibuprofen guaiacol ester
  • HY-108342
    PF-00956980 1262832-74-5 98%
    PF-00956980 is a reversible pan-JAK inhibitor with IC50 values of 2.2, 23.1 and 59.9 μM for JAK1, JAK2 and JAK3, respectively. PF-00956980 can be used in the research of lung and skin inflammatory diseases.
    PF-00956980
  • HY-108346
    JX401 349087-34-9 98%
    JX401 is a potent inhibitor of p38alpha, containing a 4-benzylpiperidine motif. p38alpha is hyperactive in inflammatory diseases, and various indications suggest that its inhibition would reverse inflammation. JX401 has the potential for the research of inflammation.
    JX401
Cat. No. Product Name / Synonyms Application Reactivity