2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-128382
    Brilliant Black BN 2519-30-4 ≥98.0%
    Brilliant black BN (E151) is an azo dye and a food colorant. Brilliant black BN is a promising antiviral agent against EV71 infection via inhibiting the interaction between EV71 and its cellular uncoating factor cyclophilin A. Brilliant black BN has the potential for the investigation of contagious disease.
    Brilliant Black BN
  • HY-131150
    Ristomycin sulfate 11140-99-1 ≥99.0%
    Ristomycin sulfate is a glycopeptide antibiotic isolated from Nocardia lurida.
    Ristomycin sulfate
  • HY-144093
    HPK1-IN-26 2229042-24-2 ≥98.0%
    HPK1-IN-26 is a HPK1 and GLK inhibitor extracted from patent WO2021254118A1 compound 1. HPK1-IN-26 can be used for the research of animal pathogen infection.
    HPK1-IN-26
  • HY-150166
    ClpB-IN-1 1453172-23-0 98.00%
    ClpB-IN-1 (compound 7) is a potent ClpB inhibitor. ClpB-IN-1 is a potential antibacterial agents.
    ClpB-IN-1
  • HY-150521
    Hispolon 173933-40-9 99.67%
    Hispolon, a polyphenol, can be isolated from Phellinus linteus. Hispolon possesses anticancer, antidiabetic, antioxidant, antiviral, hepatoprotective, anti-diabetic, and anti-inflammatory activities.
    Hispolon
  • HY-155048
    BDM91270 2892824-11-0 99.80%
    BDM91270 (compound 29) is an E. coli AcrAB-TolC efflux pump inhibitor with an EC90 of 0.6 μM for wild-type E. coli AcrB. BDM91270 can be used in the study of Escherichia coli drug resistance.
    BDM91270
  • HY-156048
    Trifluoromethyl-tubercidin 1854086-05-7 99.12%
    Trifluoromethyl-tubercidin (TFMT) is an inhibitor of 2'-O-ribose methyltransferase 1 (MTr1). Trifluoromethyl-tubercidin can inhibit the replication of influenza A and B viruses by interfering with the cap-snatching process of the influenza virus. Trifluoromethyl-tubercidin has antiviral activity and low toxicity.
    Trifluoromethyl-tubercidin
  • HY-161296
    TH6342 99.15%
    TH6342 is a SAMHD1 modulator that binds to pretetrameric SAMHD1 and prevents its oligomerization and allosteric activation. SAMHD1 is a dNTP triphosphohydrolase and an HIV-1 restriction factor. SAMHD1 can limit the replication of retroviruses and DNA viruses and has antiviral effects. The inhibitory mechanism of TH6342 does not occupy the SAMHD1 nucleotide-binding pocket, gently binds the target, and functions as a chemical probe.
    TH6342
  • HY-A0248A
    Polymyxin B1 4135-11-9
    Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment.
    Polymyxin B1
  • HY-A0279A
    Pristinamycin IA 3131-03-1 98.91%
    Pristinamycin IA (Mikamycin B) is a cycle-peptidic macrolactone antibiotic. Pristinamycin IA is a substrate of P-glycoprotein and inhibits its function. Pristinamycin IA is active against StaphyloEoccus and Srreptococcus.
    Pristinamycin IA
  • HY-B0186B
    Cefoselis sulfate 122841-12-7 99.25%
    Cefoselis sulfate (FK-037), the fourth gen-eration of cephalosporin, is a β-lactam antibiotic. Cefoselis sulfate exhibits good activity against a wide range of Gram-positive and Gram-negative organisms. Cefoselis sulfate penetrates the blood-brain barrier.
    Cefoselis sulfate
  • HY-B0260R
    Methylprednisolone (Standard) 83-43-2 99.67%
    Methylprednisolone (Standard) is the analytical standard of Methylprednisolone. This product is intended for research and analytical applications. Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties. Methylprednisolone improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels.
    Methylprednisolone (Standard)
  • HY-B0275A
    Oxytetracycline hydrochloride 2058-46-0 98.92%
    Oxytetracycline hydrochloride is an antibiotic belonging to the tetracycline class. Oxytetracycline hydrochloride potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline hydrochloride is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline hydrochloride also possesses anti-HSV-1 activity.
    Oxytetracycline hydrochloride
  • HY-B0421A
    Mycophenolic acid sodium 37415-62-6 99.98%
    Mycophenolic acid sodium is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 µM. Mycophenolic acid sodium demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid sodium is an immunosuppressive agent. Antiangiogenic and antitumor effects.
    Mycophenolic acid sodium
  • HY-B0466B
    Cloxacillin sodium 642-78-4 ≥98.0%
    Cloxacillin sodium is an orally active antibacterial agent and β-lactamase inhibitor with an IC50 of 0.04 µM. Cloxacillin sodium can suppress the S. aureus-induced inflammatory response by inhibiting the activation of MAPKs, NF-кB and NLRP3-related proteins.
    Cloxacillin sodium
  • HY-B0497C
    Niclosamide olamine 1420-04-8 99.44%
    Niclosamide (BAY2353) olamine is an orally active antihelminthic agent used in parasitic infection research. Niclosamide olamin is a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells. Niclosamide olamin has biological activities against cancer, and inhibits DNA replication in Vero E6 cells.
    Niclosamide olamine
  • HY-B0724A
    Pazufloxacin mesylate 163680-77-1 99.90%
    Pazufloxacin (T-3761) mesylate is a fluoroquinolone antibiotic.
    Pazufloxacin mesylate
  • HY-B1864A
    Kasugamycin hydrochloride 19408-46-9 99.95%
    Kasugamycin (Ksg) hydrochloride hydrate is an antibiotic that binds to 30s and 70s ribosomes but not to the 50s subunit, and has anti-infective activity. Kasugamycin hydrochloride hydrate mimics mRNA nucleotides, disrupts tRNA binding and inhibits canonical translation initiation. Kasugamycin hydrochloride hydrate increases the sensitivity of mycobacteria to Rifampicin (HY-B0272) in vitro and in mouse infection models.
    Kasugamycin hydrochloride
  • HY-B2144H
    Chitosan hydrochloride (80%-90% deacetylated) 70694-72-3
    Chitosan hydrochloride 80%-90% deacetylated (Chitosan HCl 80%-90% deacetylated) is the deacetylated, hydrocholoride form of chitosan. Chitosan hydrochloride 80%-90% deacetylated is a polysaccharide obtained by deacetylating chitin, and exhibits antimicrobial activity against various bacteria and fungi. Chitosan hydrochloride 80%-90% deacetylated is utilized in agriculture, water treatment and pharmaceutical aspects.
    Chitosan hydrochloride (80%-90% deacetylated)
  • HY-B2171A
    Carubicin hydrochloride 52794-97-5 98.33%
    Carubicin hydrochloride is a microbially-derived compound. Carubicin hydrochloride is an effective inhibitor of VHL-defective (VHL−/−) CCRCC cell proliferation. Carubicin hydrochloride also induces apoptosis by a mechanism independent of p53 or hypoxia-inducible factor HIF2. Carubicin hydrochloride has the potential for the research of cancer diseases.
    Carubicin hydrochloride
Cat. No. Product Name / Synonyms Application Reactivity