2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-169501
    WIN 62577 138091-43-7 98%
    WIN 62577 is a species-selective tachykinin NK1 receptor antagonist. WIN 62577 is also an allosteric enhancer with micromolar potency at M3 receptors. WIN 62577 exhibits potent antiviral activity against SARS-CoV-2.
    WIN 62577
  • HY-169506
    Angolamycin 1402-83-1 98%
    Angolamycin is a basic macrolide antibiotic active against Gram-positive bacteria.
    Angolamycin
  • HY-169510
    Aurachin C 108354-14-9 98%
    Aurachin C is an isoprenoid quinoline alkaloid with antiplasmodial, antifungal and antibacterial effects. Aurachin C is a selective terminal oxidases inhibitor.
    Aurachin C
  • HY-169521
    DNA Gyrase-IN-16 756843-31-9 98%
    DNA Gyrase-IN-16 (Compound 9) is the inhibitor for DNA gyrase with an IC50 of 1.609 μM. DNA Gyrase-IN-16 exhibits antibacterial activity, inhibits S. aureus and MRSA with MIC of 3.125 μM and 3.125 μM.
    DNA Gyrase-IN-16
  • HY-169551
    ATPase-IN-5 401590-85-0 98%
    ATPase-IN-5 (compound 11) is a potent inhibitor of Pma1p-ATPase, with the IC50 of 12.7 μM. ATPase-IN-5 plays an important role in anti-fungal research.
    ATPase-IN-5
  • HY-169571
    Antimicrobial agent-38 430444-03-4 98%
    Antimicrobial agent-38 (compound 10) is a potent inhibitor of methicillin-resistant S. aureus strain ATCC 700699 and nonresistant strain ATCC 29213, with MICs of 32 and 64 mg/L.
    Antimicrobial agent-38
  • HY-169587
    Protein kinase G inhibitor-3 331964-66-0 98%
    Protein kinase G inhibitor-3 (Compound 177) is an inhibitor of mycobacterial serine/threonine protein kinases. Protein kinase G inhibitor-3 can be used in the research of diseases related to mycobacterial infections.
    Protein kinase G inhibitor-3
  • HY-169635
    Mycobacterium Tuberculosis-IN-6 260428-61-3 98%
    Mycobacterium Tuberculosis-IN-6 (compound b1) is an inhibitor of Mycobacterium tuberculosis enoyl reductase InhA, with IC50 of 7.74 μM. Mycobacterium Tuberculosis-IN-6 can be used for antibacterial research.
    Mycobacterium Tuberculosis-IN-6
  • HY-169657
    UMPK ligand 1 1621866-83-8 98%
    UMPK ligand 1 (ZINC07785412) is a ligand for uridine monophosphate kinase (UMPK).
    UMPK ligand 1
  • HY-169684
    Vaccarin C 177602-12-9 98%
    Vaccarin C (Compound VIII) is a cycloheptapeptide with good antifungal activity against pathogenic fungi and dermatophytes M. audouinii and T. mentagrophytes with MIC values of 6 µg/mL. Vaccarin C also has high cytotoxicity against Dalton's lymphoma ascites (DLA) and Ehrlich's ascites carcinoma (EAC) cell lines with IC50 values of 3.35 and 5.72 μM, respectively.
    Vaccarin C
  • HY-169697
    Thiocillin 4414-51-1 98%
    Thiocillin is a thiopeptide class of RiPPs and anti-bacterial agent. Thiocillin targets the bacterial 50S ribosome. Thiocillin exhibits potent antibacterial activity against a number of agent resistant pathogens.
    Thiocillin
  • HY-169745
    9,12,13-Trihydroxy-10-octadecenoic acid 29907-56-0 98%
    9,12,13-Trihydroxy-10-octadecenoic acid is an antimicrobial agent.
    9,12,13-Trihydroxy-10-octadecenoic acid
  • HY-169746
    Antiviral agent 63 1613591-70-0 98%
    Antiviral agent 63 is a nucleoside analog with anti-HCV activity. Antiviral agent 63 can inhibit viral replication by inhibiting the activity of HCV RNA-dependent RNA polymerase or other virus-related enzymes.
    Antiviral agent 63
  • HY-16974R
    Afoxolaner (Standard) 1093861-60-9
    Afoxolaner (Standard) is the analytical standard of Afoxolaner. This product is intended for research and analytical applications. Afoxolaner is an orally active isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect γ-aminobutyric acid receptor (GABA) and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod.
    Afoxolaner (Standard)
  • HY-169790
    Phomarin 6866-87-1 98%
    Phomarin is an inhibitor for dihydrofolate reductase (DHFR), and exhibits potential antimalarial activity.
    Phomarin
  • HY-169810
    PKZ18 849658-87-3 98%
    PKZ18 is an antibiotic and inhibits bacterial growth, with MIC values of 32-64 μg/mL against most Gram-positive bacteria. PKZ18 inhibits in vivo transcription and translation of glycyl-tRNA synthetase mRNA. PKZ18 selectively targets stem I specifier loops in Gram-positive bacteria and directly reduces T-box transcriptional read-through of the associated genes. PKZ18 prevents the codon-anticodon reading required for tRNA binding and is refractory to resistance.
    PKZ18
  • HY-169811
    CPW-86-363 84080-55-7 98%
    CPW-86-363 is a novel broad-spectrum cephalosporin with antibacterial activity.
    CPW-86-363
  • HY-169812
    Dihydrobiochanin A 83920-62-1 98%
    Dihydrobiochanin A has antifungal activity. Dihydrobiochanin A is a flavonoid that can isolated from Swartzia polyphylla.
    Dihydrobiochanin A
  • HY-169815
    HCV NS5B polymerase-IN-2 438476-59-6 98%
    HCV NS5B polymerase-IN-2 (Compound 298) is a Ns5b polymerase inhibitor. HCV NS5B polymerase-IN-2 is promising for research of hepatitis C virus (HCV) infections.
    HCV NS5B polymerase-IN-2
  • HY-169816
    MMV03 375394-80-2 98%
    MMV03 is an anti-malaria agent, and is active against P. falciparum (EC50: 0.6 μM).
    MMV03
Cat. No. Product Name / Synonyms Application Reactivity