2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-156464
    Topoisomerase I inhibitor 10 98%
    Topoisomerase I inhibitor 10 (compound 13) is a leishmanial topoisomerase IB inhibitor. Topoisomerase I inhibitor 10 has antileishmanial activity against L. donovani promastigotes, with the IC50 of 27.91 μM.
    Topoisomerase I inhibitor 10
  • HY-15662R
    Tulathromycin A (Standard) 217500-96-4
    Tulathromycin A (Standard) is the analytical standard of Tulathromycin A. This product is intended for research and analytical applications. Tulathromycin A (Tulathromycin), a macrolide antibiotic, inhibits protein synthesis (IC50=0.26 μM) by targeting bacterial ribosome. Tulathromycin A is used for the research of respiratory disease in cattle and swine. Immunomodulatory effects.
    Tulathromycin A (Standard)
  • HY-15662S
    Tulathromycin A-d7 98%
    Tulathromycin A-d7 (Tulathromycin-d7) is deuterium labeled Tulathromycin A. Tulathromycin A (Tulathromycin), a macrolide antibiotic, inhibits protein synthesis (IC50=0.26 μM) by targeting bacterial ribosome. Tulathromycin A is used for the research of respiratory disease in cattle and swine. Immunomodulatory effects.
    Tulathromycin A-d7
  • HY-156975
    Sulfatrozole 13369-07-8 98%
    Sulfatrozole is a sulfanilamide derivative. Sulfatrozole is an antimicrobial agent with broad-spectrum activity.
    Sulfatrozole
  • HY-157022
    SARS-CoV-2-IN-67 2997784-47-9 98%
    SARS-CoV-2-IN-67 (Compound 16), a vitamin K derivatives, has anti-SARS-CoV-2 activity (EC50: 64.8 μM in VeroE6/TMPRSS2 cells). SARS-CoV-2-IN-67 inhibits SARS-CoV-2 RdRp activity.
    SARS-CoV-2-IN-67
  • HY-157023
    RCB16007 2952530-26-4 98%
    RCB16007 is a Yellow Fever Virus (YFV) Inhibitor. RCB16007 inhibits the West Nile virus (EC50: 7.9 μM, CC50: 17 μM).
    RCB16007
  • HY-157028
    Antiparasitic agent-19 3032412-28-2 98%
    Antiparasitic agent-19 (compound 40) is a compound with broad-spectrum antiparasitic activity. Antiparasitic agent-19 has minimal toxicity against Trypanosoma brucei, Leishmania Infantum, and Trypanosoma cruzi.
    Antiparasitic agent-19
  • HY-157045
    ATP Synthesis-IN-1 98%
    ATP Synthesis-IN-1 (Compound 4), quinoline derivative, is a potent inhibitor of PA ATP synthesis activity. ATP Synthesis-IN-1 has PA ATP synthesis inhibition with IC50 value of 11.1μg/mL. ATP Synthesis-IN-1 also has antibacterial activity. ATP Synthesis-IN-1 can be used for the research of drug-resistant PA infection.
    ATP Synthesis-IN-1
  • HY-157046
    ATP Synthesis-IN-2 98%
    ATP Synthesis-IN-2 (Compound 5) is an antibacterial compound. ATP Synthesis-IN-2 is a potent ATP synthesis activity inhibitor with IC50 against Pseudomonas aeruginosa (PA) Value of 0.7 μg/mL.
    ATP Synthesis-IN-2
  • HY-157082
    ZHSI-1 2925912-67-8 98%
    ZHSI-1 is an EV71 (Enterovirus 71) inhibitor that inhibits EV71/CVA16 replication and virus-induced pyroptosis associated with viral pathogenesis. ZHSI-1 effectively prevents EV71 infection in neonatal and young mice in animal models. ZHSI-1 can be used to study viral infections such as hand, foot and mouth disease (HFMD).
    ZHSI-1
  • HY-157130
    T3SS-IN-3 98%
    T3SS-IN-3 (compound F-24) is an inhibitor of type III secretion system (T3SS). T3SS-IN-3 inhibits the transcription of hrpY gene significantly without inhibiting bacterial growth.
    T3SS-IN-3
  • HY-157141
    Antibacterial agent 163 16588-39-9 98%
    Antibacterial agent 163 (compound 1), a hydroxyquinoline derivative, is a potent bacterial inhibitor. Antibacterial agent 163 inhibits methicillin-resistant Staphylococcus aureus (MRSA).
    Antibacterial agent 163
  • HY-157142
    Antibacterial agent 165 98%
    Antibacterial agent 165 (compound 3), a hydroxyquinoline derivative, is a potent bacterial inhibitor. Antibacterial agent 165 inhibits methicillin-resistant Staphylococcus aureus (MRSA).
    Antibacterial agent 165
  • HY-157143
    Antibacterial agent 164 98%
    Antibacterial agent 164 (compound 2a) is an antibacterial and antibiofilm agent. Antibacterial agent 164 inhibits S. aureus and B. subtilis (MIC of 0.09 mM), and also exhibits strong anti-B. Subtilis biofilm formation.
    Antibacterial agent 164
  • HY-157144
    SARS-CoV-2-IN-68 2682897-84-1 98%
    SARS-CoV-2-IN-68 (compound 6C) is a covalent SARS-CoV-2 PLpro/Mpro inhibitor with potent antiviral activities. SARS-CoV-2-IN-68 binds to Zn-finger domain of PLpro.
    SARS-CoV-2-IN-68
  • HY-157145
    SARS-CoV-2-IN-69 78471-90-6 98%
    SARS-CoV-2-IN-69 (Compound 7E) is a non-covalent SARS-CoV-2 inhibitor with an EC50 value of 7.4 μM. SARS-CoV-2-IN-69 is a potent inhibitor of SARS-CoV-2 main protease (Mpro) and a non-covalent inhibitor of papain (PLpro).
    SARS-CoV-2-IN-69
  • HY-157291
    Antiviral agent 44 872201-68-8 98%
    Antiviral agent 44 (compound 7b) is an antiviral agent that has anti-HCV activity in vitro.
    Antiviral agent 44
  • HY-157300
    Antifungal agent 88 98%
    Antifungal agent 88 (compound 54) has antifungal potency with MIC values ranging from <0.125 μg/mL to 1 μg/mL.
    Antifungal agent 88
  • HY-157305
    Jun11165 98%
    Jun11165 is a SARS-CoV-2 PLpro inhibitor (IC50 ≤ 0.6 μM), which inhibits SARS-CoV-2 with an EC50 value of ≤ 6 μM. Jun11165 can be used in the research of viral infections.
    Jun11165
  • HY-157315
    Fabl inhibitor 21272541 898527-42-9 98%
    21272541 is a potent inhibitor of FabI protein. 21272541 significantly inhibits the infections caused by Gram-negative organisms.
    Fabl inhibitor 21272541
Cat. No. Product Name / Synonyms Application Reactivity