2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-129580
    Nannochelin B 133705-27-8 98%
    Nannochelin B is a novel citrate-hydroxamate siderophore with a growth-inhibitory activity against some bacteria and fungi.
    Nannochelin B
  • HY-129585
    SM-4470 89433-57-8 98%
    SM-4470 is an orally active antifungal compound. SM-4470 has inhibitory activity against yeast, Aspergillus, and dermatophytes in vitro.
    SM-4470
  • HY-129616
    TachypleginA-2 296798-88-4 98%
    TachypleginA-2 is a small-molecule inhibitor of parasite motility and invasion. TachypleginA-2 reproducibly induces the TgMLC1 (an essential light chain) mobility shift.
    TachypleginA-2
  • HY-129691
    Ro 14-1761 82502-19-0 98%
    Ro 14-1761 is a third-generation cephalosporin with antibacterial activity.
    Ro 14-1761
  • HY-129728
    Lienomycin 12710-02-0 98%
    Lienomycin, a polyene antibiotic produced by Actinomyces distatochromogenes var. lienomycini, exhibits antifungal, antibacterial and antitumor activity.
    Lienomycin
  • HY-129804
    Ceforanide (lysine) 63767-79-3 98%
    Ceforanide lysine is a second generation cephalosporin administered intravenously or intramuscularly. Ceforanide lysine has a spectrum of in vitro antibacterial activity.
    Ceforanide (lysine)
  • HY-129814
    MM 42842 free acid 113784-28-4 98%
    MM 42842 free acid is a member of the monobactam family of β-lactam antibiotics.
    MM 42842 free acid
  • HY-129836
    L-Amoxicillin 26889-93-0 98%
    L-Amoxicillin is an antibiotic with activity against a wide range of bacterial infections. L-Amoxicillin is commonly used in antibacterial combinations when used in combination with the β-lactamase inhibitor potassium clavulanic acid. The related substances analysis method for L-Amoxicillin has been developed and validated according to the International Conference on Harmonization (ICH) guidelines, ensuring its effectiveness and accuracy in mixtures. L-Amoxicillin and some of its impurities have been further analyzed in stress testing and stability studies, providing support for optimizing its application.
    L-Amoxicillin
  • HY-129900
    (-)-Luteoskyrin 21884-44-6 98%
    (-)-Luteoskyrin has a wide range of antibacterial activity, such as against malaria (with an IC50 of 0.51 μg/mL), tuberculosis (MIC of 6.25 μg/mL), and it also shows antibacterial effects (with MIC for Gram-positive bacteria ranging from 0.39 to 1.56 μg/mL, and for Gram-negative bacteria from 3.13 to 12.50 μg/mL), as well as antifungal activity (with MIC against plant pathogens ranging from 3.13 to 50μg/mL). (-)-Luteoskyrin exhibits cytotoxicity against NCI-H187 cells, with an IC50 range of 0.16–17.99 μg/mL.
    (-)-Luteoskyrin
  • HY-129952
    Dihydropleuromutilin 42302-24-9 98%
    Dihydropleuromutilin is a reduced product of Pleuromutilin, which is active against gram-positive bacteria and shows lower toxicity.
    Dihydropleuromutilin
  • HY-130059
    Guanine-7-oxide 5227-68-9 98%
    Guanine-7-oxide (Guanine 7-N-oxide) is an antitumor antibiotic with anti-tumor, anti-Candida albicans activity, and can inhibit viral replication effect of herpes virus, infectious blood virus (IHNV), infectious pancreatic necrosis virus (IPNV) and so on. Guanine-7-oxide has good activity against mouse L1210 leukemia cells.
    Guanine-7-oxide
  • HY-130280
    Ianthelliformisamine A TFA 1643593-28-5 98%
    Ianthelliformisamine A TFA is an antibiotic enhancer with activity against resistant Gram-negative bacteria. Ianthelliformisamine A TFA exhibits bactericidal activity against Staphylococcus aureus with an IC50 value of 3.8 μM (minimum inhibitory concentration = 25 μM). The biological activity of Ianthelliformisamine A TFA is derived from the structural variation of its synthetic derivatives and its coupling reaction with different amino ester derivatives.
    Ianthelliformisamine A TFA
  • HY-130317
    trans-11-Methyl-2-dodecenic acid 677354-24-4 98%
    trans-11-Methyl-2-dodecenic acid is a isomer of cis-11-Methyl-2-dodecenoic acid (HY-134215). cis-11-Methyl-2-dodecenoic acid is a quorum sensing (QS) signal that acts as a diffusion signaling factor (DSF) in extracellular microbial and fungal communication systems.
    trans-11-Methyl-2-dodecenic acid
  • HY-130323
    13-HPOT 67597-26-6 98%
    13-HPOT, a linolenic fatty acid hydroperoxide, is an antibacterial agent. 13-HPOT has a strong dose response effect on three plant pathogen gram negative bacteria: Pectobacterium carotovorum, Pseudomonas syringae and Xanthomonas translucens. 13-HPOT can interact with the lipid representative of the inner bacterial plasma membrane.
    13-HPOT
  • HY-130337
    Teicoplanin A2-2 91032-26-7 98%
    Teicoplanin A2-2 is a glycopeptide antibiotic. Teicoplanin A2-2 exhibits antibacterial activity, particularly against coagulase-negative staphylococci (CNS). Teicoplanin A2-2 inhibits bacterial cell wall synthesis by competitively binding to the terminal D-Ala-D-Ala peptide bonds in the cell wall synthesis process, leading to bacterial death. Teicoplanin A2-2 can be used for research into bacterial resistance mechanisms and the development of new antibiotics.
    Teicoplanin A2-2
  • HY-130369
    NSC10010 hydrochloride 6286-09-5 98%
    NSC10010 hydrochloride inhibits gammaherpesvirus associated B-lymphomas growth through activation of NF-kB and c-Myc-mediated signaling pathways. NSC10010 hydrochloride induces necrotic cell death in gammaherpesvirus infected B-cells. NSC10010 hydrochloride is also an inhibitor of Mtb ClpC1 ATPase.
    NSC10010 hydrochloride
  • HY-130406
    Benthiavalicarb isopropyl 177406-68-7 98%
    Benthiavalicarb isopropyl is a fungicide with specific activity against downy mildew and blight. Benthiavalicarb isopropyl is evaluated for use where necessary to control a serious threat to plant health that cannot be treated by other methods, including non-chemical methods. The use of Benthiavalicarb isopropyl can be considered representative of field applications in potatoes. Environmental and human exposures of Benthiavalicarb isopropyl are considered to be negligible.
    Benthiavalicarb isopropyl
  • HY-130431
    Vinclozolin M2 83792-61-4 98%
    Vinclozolin M2 is an active metabolite of vinclozolin. It is formed from vinclozolin by successive esterase activity and decarboxylation of vinclozolin in C. elegans and by decarboxylation in human liver microsomes. Vinclozolin M2 is an antagonist of the mineralocorticoid receptor (IC50=1,400 nM) and androgen receptor (IC50=0.17 nM) in reporter assays using MCF-7 cells.
    Vinclozolin M2
  • HY-130471
    Sannamycin C 73522-71-1 98%
    Sannamycin C is an aminoglycoside antibiotic. Sannamycin C has weak antibacterial activity against Gram-positive bacteria.
    Sannamycin C
  • HY-130484
    2,3-Dehydro-3,4-dihydro ivermectin 1135339-49-9 98%
    2,3-Dehydro-3,4-dihydro ivermectin is an analog of ivermectin (HY-15310) and an anthelmintic. 2,3-Dehydro-3,4-dihydro ivermectin has activity against L. amazonensis promastigotes and amastigotes (IC50s=13.8 and 3.6 µM, respectively) without inducing cytotoxicity to macrophages (IC50= 65.5 µM).
    2,3-Dehydro-3,4-dihydro ivermectin
Cat. No. Product Name / Synonyms Application Reactivity