2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-129209
    Myrotoxin B 99486-49-4 98%
    Myrotoxin B is a toxin produced by the fungus Myrothecium roridum that can induce necrotic lesions in mulberry leaves. Myrotoxin B can also promote the infection rate of Myrothecium roridum, acting as an infection factor, increasing the ability of the fungus to infect host plants. Myrotoxin B can be used in plant pathology and mycotoxin research.
    Myrotoxin B
  • HY-129252
    Prothracarcin 81542-99-6 98%
    Prothracarcin is an antibiotic with antitumor activity that exerts its tumor cell toxicity by covalently binding to the C-2 amino group of guanine residues in the minor groove of DNA. Prothracarcin also shows antibacterial activity against Gram-positive bacteria and some Gram-negative bacteria such as Escherichia coli.
    Prothracarcin
  • HY-129253
    GSK984 827591-04-8 98%
    GSK984 is an inactive control probe for GSK983 (HY-119098), a dihydroorotate dehydrogenase (DHODH) inhibitor with antiviral activity.
    GSK984
  • HY-129262
    Deoxypheganomycin D 69280-94-0 98%
    Deoxypheganomycin D is a specific antimycobacterial inhibitor with no cross-resistance to other antibiotics such as Paromomycin (HY-B0956), Capreomycin (HY-P3270), Viomycin (HY-A0155), Streptothricin (HY-129065), Kanamycin (HY-16566), and Streptomycin (HY-B1906). Deoxypheganomycin D (28 μM) partially inhibits the growth of Mycobacterium 607, with no significant inhibitory effects on DNA, RNA, or protein synthesis. Deoxypheganomycin D (7 μM) affects leucine influx, not thymidine, and has the opposite effect on efflux. The effects of Deoxypheganomycin D may be related to cell membrane and specific mycobacterial lipid components.
    Deoxypheganomycin D
  • HY-129280
    Janthinocin A 131086-52-7 98%
    Janthinocin A has strong activity of anti-Gram-positive bacteria and moderate anti-Gram-negative bacteria.
    Janthinocin A
  • HY-129292
    Quinocarcin 84573-33-1 98%
    Quinocarcin (DC-52) is a potent antitumor antibiotic. Quinocarcin inhibits Bacillus subtilis DNA, RNA and protein syntheses.
    Quinocarcin
  • HY-129318
    MBX-1066 868971-24-8 98%
    MBX 1066 is a potent antibacterial agent. MBX 1066 shows inhibition for Mycobacterium tuberculosis. MBX 1066 shows antibacterial activity in mice.
    MBX-1066
  • HY-129329
    Lankamycin 30042-37-6 98%
    Lankamycin, a macrolide antibiotic, shows moderate antimicrobial activity against several gram-positive bacteria, acting as a synergistic pair with carbocyclic antibiotic Lankacidin C (HY-121412) by binding to the ribosome exit tunnel.
    Lankamycin
  • HY-129331
    Neothramycin A 59593-16-7 98%
    Neothramycin A is an antibiotic, which can be isolated from Streptomyces. Neothramycin A exhibits board spectrum antimicrobial activity, inhibits Staphylococcus aureus, Klebsiella pneumoniae, Escherichia coli W677, and Saccharomyces cerevisia with MIC of 25-50 μg/mL. Neothramycin A exhibits antitumor efficacy against leukemia in mouse models.
    Neothramycin A
  • HY-129339
    Akrobomycin 89156-94-5 98%
    Akrobomycin is an anthracycline antibiotic. Akrobomycin shows antimicrobial and antitumor activities.
    Akrobomycin
  • HY-129342
    Lincomycin B 2520-24-3 98%
    Lincomycin B is an antibiotic that can be isolated from Streptomyces lincolnensis.
    Lincomycin B
  • HY-129347
    Lankacyclinol A 52212-91-6 98%
    Lankacyclinol A is an orally active antibiotic isolated from Streptomyces rochei. Lankacyclinol A has broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria. Lankacyclinol A exhibits low toxicity in mice.
    Lankacyclinol A
  • HY-129407
    AAF-CMK TFA 184901-82-4 98%
    AAF-CMK TFA (Ala-ala-phe-chloromethylketone tfa; N-Ala-Ala-Phe-CMK) is a subtilisin-type serine peptidase that removes tripeptides from the free NH2 termini of oligopeptides. AAF-CMK TFA is an irreversible inhibitor of TPPII and is typically used at concentrations of 10-100 μM. It does not significantly interfere with the chymotrypsin-like activity of the proteasome. AAF-CMK also inhibits bleomycin hydrolase and puromycin-sensitive aminopeptidase when used at a concentration of 50 μM.
    AAF-CMK TFA
  • HY-129432
    (-)-Deacetylsclerotiorin 61248-35-9 98%
    (-)-Deacetylsclerotiorin (Compound 30) is the enantiomer of Deacetylsclerotiorin (HY-126167). Deacetylsclerotiorin is the metabolite of chloramphenicol isolated from the fungus Bartalinia robillardoides strain LF550. Deacetylsclerotiorin has significant inhibitory effects on Candida albicans (IC50=24 μM), Trichophyton rubrum (IC50=2.83 μM) and Septoria tritici (IC50=7.45 μM). In addition, Deacetylsclerotiorin also exhibits inhibitory effects on the enzyme phosphodiesterase 4 (PDE4) (IC50=2.8 μM).
    (-)-Deacetylsclerotiorin
  • HY-129435
    Altromycin E 134887-77-7 98%
    Altromycin E is an antibiotic, that exhibits antibacterial against Streptococci and Staphylococci with MIC of 0.2-3.12 μg/mL. Altromycin E can be used in anti-tumor research.
    Altromycin E
  • HY-129469
    Saframycin S 75425-66-0 98%
    Saframycin S is an antibiotic with a racemomycin group that exhibits inhibitory activity against Ehrlich ascites tumors. The LD50 of Saframycin S in ddY mice is 3.2 mg/kg (i.p.).
    Saframycin S
  • HY-129487
    (E/Z)-MC4 219140-31-5 98%
    (E/Z)-MC4 is an enantiomer of the antibacterial agent MC4, which has antibacterial activity against a group of Staphylococcus aureus strains including MRSA, and has no significant toxicity to mammalian cells.
    (E/Z)-MC4
  • HY-129493
    Lateropyrone 93752-78-4 98%
    Lateropyrone is a type of pyranone antibiotic that can inhibit Gram-negative bacteria, and it's a secondary metabolite produced by the oat fungal pathogen.
    Lateropyrone
  • HY-129548
    Prumycin 38819-28-2 98%
    Prumycin is an antifungal antibiotic with activity against cucumber powdery mildew. Prumycin significantly inhibited the disease, whereas other metabolites such as bacillomycin D and surfactin did not. Prumycin did not induce the expression of plant defense genes, indicating that its effects were not through plant defense responses. Observation of cucumber cotyledons treated with prumycin showed that it could inhibit spore germination of P. fusca.
    Prumycin
  • HY-129563
    CGP 57813 150608-41-6 98%
    CGP 57813 is a peptidomimetic inhibitor of HIV protease that can be encapsulated by nanoparticles composed of poly(D,L-lactic acid) (PLA) and pH-sensitive methacrylic acid copolymers and delivered into the body.
    CGP 57813
Cat. No. Product Name / Synonyms Application Reactivity