2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-126803
    Saquayamycin B 99260-67-0 98%
    Saquayamycin B (compound 3) is a new angucycline antibiotic. Saquayamycin B has antitumor activities against a human lung (H-460) and a human breast cancer cell line (MCF-7) with GI50 values of 12.2 and 15.2 µM respectively .
    Saquayamycin B
  • HY-126877
    3-Deaza-2'-deoxyadenosine 78582-17-9 98%
    3-Deaza-2 '-deoxyadenosine is a nucleoside analog synthesized from 2' -deoxyadenosine. 3-Deaza-2 '-deoxyadenosine inhibits RNA synthesis by binding to ribose fragments of ribonucleotides, thereby preventing the formation of enzyme-substrate complexes, thereby preventing chain elongation, It can also inhibit DNA synthesis by binding deoxyribose fragments of DNA and preventing DNA polymerase from adding nucleotides to the growth chain. 3-Deaza-2 '-deoxyadenosine has antiviral activity.
    3-Deaza-2'-deoxyadenosine
  • HY-126878
    11-Oxahomoaminopterin 78520-72-6 98%
    11-Oxahomoaminopterin shows antifolate activity and inhibits Lactobacillus casei DHFFZ with antimicrobial and antitumor activities.
    11-Oxahomoaminopterin
  • HY-126914
    Diacetylcercosporin 62574-06-5 98%
    Diacetylcercosporin is a perylenequinone produced by Cercospora and Septoria that has diverse biological activities. Diacetylcercosporin inhibits the growth of P. falciparum strains that are sensitive and resistant to chloroquine (IC50s=2.75 and 1.94 μM for D6 and W2 clones, respectively) and L. donovani parasites (IC50=3.1 μM) in vitro. Diacetylcercosporin exhibits cytotoxicity against SK-MEL, KB, BT549, and SKOV3 human cancer cell lines (IC50s=4.8-8.7 μM). Diacetylcercosporin is also a phytotoxin that inhibits the growth of lettuce and bentgrass at a concentration of 1.62 mM.
    Diacetylcercosporin
  • HY-126954
    13-Deoxycarminomycin 76034-18-9 98%
    13-Deoxycarminomycin is an antibiotic with antibacterial activity. 13-Deoxycarminomycin also exhibits cytotoxicity against tumor cells such as HeLa and P388, and can play an anti-tumor role.
    13-Deoxycarminomycin
  • HY-127000
    Julifloricine 66771-80-0 98%
    Julifloricine is an alkaloid from Prosopis juliflora. Julifloricine has antibacterial activity.
    Julifloricine
  • HY-127014
    Julimycin B2 18126-05-1 98%
    Julimycin B2 has anti-Gram-positive bacteria and anti-virus activity and it has effects on ehrman ascites carcinoma in mice.
    Julimycin B2
  • HY-127020
    Deoxyenterocin 108605-51-2 98%
    Deoxyenterocin is a bacterial metabolite originally isolated from Streptomyces that has diverse biological activities, including antibiotic, antiviral, and antioxidant properties. It inhibits the growth of S. lutea, S. aureus, K. pneumoniae, and V. percolans in vitro when used at a concentration of 500 μg/mL. Deoxyenterocin (50 μg/mL) inhibits the cytopathic effect of influenza A H1N1 virus by 60.6% in vitro. It also prevents hydrogen peroxide-induced decreases in glutathione (GSH) levels and in the mitochondrial membrane potential in mouse primary cortical neuronal cultures when used at a concentration of 1 μM.
    Deoxyenterocin
  • HY-127028
    Tripynadine 81849-98-1 98%
    Tripynadine is an anti-malarial compound with oral activity.
    Tripynadine
  • HY-127072
    Amicoumacin A 78654-44-1 98%
    Amicoumacin A is a antibiotic that can be isolated from the culture of Bacillus pumilus BN-103.
    Amicoumacin A
  • HY-127093
    Sedecamycin 23477-98-7 98%
    Sedecamycin is an antibiotic, which exhibits antibacterial activity against gram-positive bacteria. Sedecamycin inhibits Treponema hyodysenteriae, with MIC of 0.78 to 12.5 µg/ml. Sedecamycin exhibits protective and therapeutic effect against the swine dysentery in mouse models.
    Sedecamycin
  • HY-127131
    Leucanicidin 91021-66-8 98%
    Leucanicidin is a macrolide bacterial metabolite originally isolated from S. halstedii. It is toxic to L. separata fourth instar larvae when used at a concentration of 20 ppm and to H. contortus, T. colubriformis, and O. circumcincta larvae (LD50s=0.23-0.42 μg/mL).
    Leucanicidin
  • HY-127140
    Cardanol triene 79353-39-2 98%
    Cardanol triene is a phenol found in cashew nut shell liquid that reversibly inhibits tyrosinase with an IC50 value of 40.5 μM in vitro. A mixture of cardanol mono-, di-, and triene is used to synthesize cardanol-metal complexes that inhibit uropathogenic E. coli biofilm formation.
    Cardanol triene
  • HY-12772A
    rel-Hydroxy Itraconazole 207970-87-4 98%
    rel-Hydroxy Itraconazole (rel-R-63373) is a relative stereoisomer of Hydroxy Itraconazole. Hydroxy Itraconazole is the major active metabolite of the antifungal compound Itraconazole (HY-17514).
    rel-Hydroxy Itraconazole
  • HY-12785R
    Albendazole sulfoxide (Standard) 54029-12-8
    Albendazole sulfoxide (Standard) is the analytical standard of Albendazole sulfoxide. This product is intended for research and analytical applications. Albendazole sulfoxide (Ricobendazole), the main active metabolite of Albendazole, exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes.
    Albendazole sulfoxide (Standard)
  • HY-128189
    Aminoacyl tRNA synthetase-IN-4 342017-94-1 98%
    Aminoacyl tRNA synthetase-IN-4 (Compound 1l) is an inhibitor of Aminoacyl tRNA synthetase, with an IC50 of 0.026 μM for C.albicans prolyl-tRNA synthetase. Aminoacyl tRNA synthetase-IN-4 can be used for antifungal research.
    Aminoacyl tRNA synthetase-IN-4
  • HY-128509
    Dioxidine 17311-31-8
    Dioxidine is an antibacterial agent. Dioxidine inhibits the growth of bacteria Dioxidine can be usde for suppurative infections study.
    Dioxidine
  • HY-128514
    Minimycin 32388-21-9 98%
    Minimycin (Oxazinomycin) is a nucleoside antibiotic with a broad-spectrum antibacterial activity. Minimycin has inhibitory effect on mouse Ehrlich ascites carcinoma, ascites type and solid type sarcoma-180.
    Minimycin
  • HY-129124
    β-​Solamarine 3671-38-3 98%
    β-?Solamarine is an antibacterial agent.
    β-​Solamarine
  • HY-129130
    Canthin-6-one N-oxide 60755-87-5 98%
    Canthin-6-one N-oxide (Canthin-6-one 3-oxide) is an orally active antiparasitic agent with limited activity.
    Canthin-6-one N-oxide
Cat. No. Product Name / Synonyms Application Reactivity