2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-12651S
    Primaquine-d3 diphosphate 98%
    Primaquine-d3 (diphosphate) is the deuterium labeled Primaquine diphosphate. Primaquine Diphosphate (Primaquine phosphate), an 8-aminoquinoline, exerts a broad spectrum of activities against various stages of parasitic malaria. Primaquine Diphosphate remains as the only agent that destroys late hepatic stages and latent tissue forms of Plasmodium vivax and Plasmodium ovale.
    Primaquine-d3 diphosphate
  • HY-126579
    Dactylocycline E 146064-01-9 98%
    Dactylocycline E has anti-Gram-positive bacteria activity.
    Dactylocycline E
  • HY-126602
    Kinamycin B 35303-13-0 98%
    Kinamycin B is an antibiotic found in Streptomyces murayamaensis of the genus Streptomyces that exhibits antifungal activity.
    Kinamycin B
  • HY-126603
    Asperlactone 76375-62-7 98%
    Asperlactone has anti-inflammatory activity. Asperlactone inhibits superoxide anion generation. Asperlactone is a fungal metabolite that can be isolated from isolated from Aspergillus ochraceus.
    Asperlactone
  • HY-126605
    Trinactin 7561-71-9 98%
    Trinactin is a macrotetrolide antibiotic. Trinactin also is a cation carrier.
    Trinactin
  • HY-126610
    Dactylfungin A 146935-35-5 98%
    Dactylfungin A, an α-pyrone-containing antifungal agent found in Dactylaria parvispora.
    Dactylfungin A
  • HY-126634
    Lyngbyatoxin B 133084-52-3 98%
    Lyngbyatoxin B is a complex compound in a versatile biosynthetic pathway from the marine cyanobacterium Moorea producens. By heterologously expressing the lyngbyatoxin biosynthetic pathway in Escherichia coli, lyngbyatoxin A (25.6 mg/L) and its precursor indolactam-V (150 mg/L) were successfully produced. This approach confirmed the biosynthetic route of lyngbyatoxin and laid a chemical foundation for future pathway engineering. In addition, the successful production of lyngbyatoxin A in E. coli opens the possibility for heterologous expression and characterization of other cyanobacterial natural products.
    Lyngbyatoxin B
  • HY-126637
    Marasmic acid 2212-99-9 98%
    Marasmic acid is a sesquiterpenoid with unsaturated dialdehyde functionality, first isolated from the Basidiomycete Marasmus conigenus. Marasmic acid has antibacterial, antifungal, cytotoxic and mutagenic activities, and its broad-spectrum activity is related to the α,β-unsaturated aldehyde group. However, its detailed biological mechanism of action has not been clarified. Previous studies have suggested that marasmic acid may exert its effects by reacting with endogenous nucleophiles or forming pyrrole derivatives. This study found that marasmic acid interferes with the membrane sensor histidine kinase MoSln1p of M. oryzae, superactivates the HOG pathway and causes cell death, indicating that its mechanism of action is different from other unsaturated dialdehyde sesquiterpenoids.
    Marasmic acid
  • HY-126638
    Marcfortine A 75731-43-0 98%
    Marcfortine A is an indole alkaloid originally isolated from P. roqueforti. It has nematocidal activity against the parasitic nematode H. contortus (LD99=0.06 μg/mL) and inhibits motility of adult worms (EC50=2 μM). Marcfortine A eliminates H. contortus, T. colubriformis, and O. ostertagi from experimentally infected jirds (ED95s=0.33, 0.11, and 2.5 mg/animal, respectively). It dose-dependently inhibits nicotine-induced calcium mobilization in SH-SY5Y and TE-671 cells expressing α3 subunit-containing human nicotinic acetylcholine receptors (nAChRs) and muscle-type nAChRs, respectively.
    Marcfortine A
  • HY-126644
    Halocyamine B 122548-04-3 98%
    Halocyamine B exhibits antimicrobial activity against a variety of bacteria and yeasts. Halocyamine B exhibits cytotoxicity to cultured neural cells of rat fetal brain, mouse neuroblastoma N18 cells, and human hepatoma HepG2 cells.
    Halocyamine B
  • HY-126660
    Cinerubin A 34044-10-5 98%
    Cinerubin A (Cinerubine A) has anti-Gram-positive bacteria, mycobacterium, fungis and amoeba activity, and has strong effect on mouse adenocarcinoma E0771.
    Cinerubin A
  • HY-126695
    Altromycin B 128461-00-7 98%
    Altromycin B is a member of the pluramycin antibiotic family isolated from South African bush soil. Altromycin B shows selective antibacterial activity against Gram-positive bacteria and has in vivo activity against P388 leukemia, colon cancer, lung cancer, and ovarian cancer.
    Altromycin B
  • HY-126724
    Flutianil 958647-10-4 98%
    Flutianil is a fungicide, which specifically inhibits the powdery mildew species. Flutianil inhibits the haustorium formation and subsequent mycelia growth.
    Flutianil
  • HY-126735
    Saquayamycin D 99260-71-6 98%
    Saquayamycin D is an antibiotic, which can be isolated from Streptomyces nodosus culture broth. Saquayamycin D exhibits antibacterial activity against various gram-positive bacteria with MIC of 12.5-50 μg/mL. Saquayamycin D inhibits the proliferation of Doxorubicin (HY-15142)-sensitive P388/S and Doxorubicin-resistant P388/ADR with IC50 of 0.15 and 0.15 μg/mL.
    Saquayamycin D
  • HY-126745
    Corynecin V 40958-12-1 98%
    Corynecin V is a chloramphenicol-like bacterial metabolite originally isolated from Corynebacterium.
    Corynecin V
  • HY-126746
    Corynecin I 4423-58-9 98%
    Corynecin I is an antibiotic produced by Corynebacterium hydrocarboclastus, and its precursor (D-(-) threo-p-amino phenyl serinol-N-acetylamine) has a minimal inhibitory effect on the synthesis of Corynecin from mevalonic acid.
    Corynecin I
  • HY-126747
    Corynecin IV 40958-11-0 98%
    Corynecin IV is a chloramphenicol-like bacterial metabolite originally isolated from Corynebacterium.
    Corynecin IV
  • HY-126770
    Rhizocticin A 114301-25-6 98%
    Rhizocticin A is an antifungal phosphono-oligopeptide against Ascodesmis, Plicaria, Rhizoctonia with MIC of 3.5 μg/mL. Rhizocticin A produces toxic L-2-Amino-5-phospho-3-cis-pentenoic acid (L-APPA), which may interfere with cell metabolism.
    Rhizocticin A
  • HY-126788
    Antibiotic DC 102 115722-50-4 98%
    Antibiotic DC 102 is a new glycosidic pyrrole(1,4)benzodiazepine antibiotic with a MIC value of 42 μg/mL target Bacillus subtilis No. 10707. Antibiotic DC 102 has an LD50 value of 1.5mg/mL(i.p) in mouse.
    Antibiotic DC 102
  • HY-126802
    Saquayamycin B1 99260-68-1 98%
    Saquayamycin B1 has antimicrobial effect, but it has weaker effect against Gram-negative bacteria. Saquayamycin B1 has inhibitory effect on leukemia P388 cells and Adriamycin-resistant P388 cells.
    Saquayamycin B1
Cat. No. Product Name / Synonyms Application Reactivity