2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-120157
    Vif-ElonginC interaction inhibitor 1 374679-27-3 98%
    Vif-ElonginC interaction inhibitor 1 (compound VEC-5) is a potent Vif inhibitor. Vif-ElonginC interaction inhibitor 1 can restrict HIV-1 in Vif-nonpermissive cells. Vif-ElonginC interaction inhibitor 1 can protect A3G, APOBEC3C (A3C), and APOBEC3F (A3F) from Vif-mediated degradation and drastically inhibit Vif function through blocking the interaction between Vif and ElonginC. Vif-ElonginC interaction inhibitor 1 enhances A3G incorporation into HIV-1 virions to reduce viral infectivity.
    Vif-ElonginC interaction inhibitor 1
  • HY-120203
    DA 1131 169285-98-7 98%
    DA 1131 is an anionic Carbapenem antibiotic. DA 1131 has broad spectrum antibacterial activity for both gram-positive and gram-negative organisms. DA 1131 is resistant to degradation by various types of β-lactamases.
    DA 1131
  • HY-120233
    MK-8876 1426960-33-9 98%
    MK-8876 is an inhibitor of HCV NS5b site D, which can be used in the research of hepatitis C virus .
    MK-8876
  • HY-120242
    N-(3-Oxobutanoyl)-L-homoserine lactone 148433-27-6 98%
    N-(3-Oxobutanoyl)-L-homoserine lactone (3-oxo-C4-HSL) is a carbapenem antibiotic biosynthesis autoregulator in Erwinia carotovora ATCC 39048. N-(3-Oxobutanoyl)-L-homoserine lactone induces expression of rhiI in R. leguminosarum.
    N-(3-Oxobutanoyl)-L-homoserine lactone
  • HY-120316
    AB3127-C 139159-01-6 98%
    AB3127-C is an anti-mite agent that can be isolated from Streptomyces platensis AB3217. AB3127-C exerts a protection coefficient of 90% at a concentration of 100 μg/mL.
    AB3127-C
  • HY-120366
    WCK-5153 1452460-79-5 98%
    WCK-5153 is a Penicillin-Binding Protein 2 (PBP2) inhibitor with an IC50 of 0.14 μg/ml (for P. aeruginosa PBP2) and acts as a β-lactam enhancer against Pseudomonas aeruginosa. WCK-5153 can be used in studies of multidrug-resistant (MDR) pathogens.
    WCK-5153
  • HY-120450
    CL-55 1370706-59-4 98%
    CL-55 is an inhibitor for type three secretion system of Chlamydia trachomatis, that blocks the effector molecules delivery of bacteria into host cells. CL-55 ameliorates the C. trachomatis infection and inflammation in mice.
    CL-55
  • HY-120462
    Genz-669178 1254834-91-7 98%
    Genz-669178 is an inhibitor for dihydroorotate dehydrogenase (DHODH) with IC50 of 0.015-0.05 μM in Plasmodium spp.. Genz-669178 inhibits P. berghei, P. falciparum strains 3D7 and Dd2 with IC50 of 0.068, 0.008 and 0.01 μM, respectively. Genz-669178 exhibits anti-malarial efficacy in P. berghei-infected mice with ED50 of 13-21 mg/kg/day. Genz-669178 exhibits good pharmacokinetic characteristics in mice.
    Genz-669178
  • HY-120550
    RS 49676 111962-89-1 98%
    RS 49676 is an N-substituted imidazole compound that exhibits strong in vitro activity against endogenous amoebae (ED50 < 0.1 ng/mL), but is ineffective against exogenous amoebae (epimastigotes). In vivo, RS 49676 (100 mg/kg/d, sc, 2 times) can prolong the average survival time of mice infected with Trypanosoma cruzi to more than 11 weeks.
    RS 49676
  • HY-120555
    Texaline 115070-72-9 98%
    Texaline is a active product that can be isolated from Amyris species of plants in the Caribbean. Texaline has antitubercular activity.
    Texaline
  • HY-120579
    A 53868A 116198-48-2 98%
    A 53868A is an antibiotic and can be isolated from Streptomyces luridus.
    A 53868A
  • HY-120583
    (Rac)-LY 255262 106892-82-4 98%
    (Rac)-LY 255262 is a pyrazolidinone-derivative that has antibacterial activity.
    (Rac)-LY 255262
  • HY-120650
    CAY10435 288862-73-7 98%
    CAY10435 is a β-ketooxazapyridine, selective FAAH inhibitor with antimicrobial activity. CAY10435 binds non-competitively to the FAAH of Dictyostelium discoideum with a Kd value of 0.57 nM.
    CAY10435
  • HY-120658
    (Rac)-LY193239 122548-63-4 98%
    (Rac)-LY193239 is a racemic modification of LY193239 (HY-120658A). LY193239 is a higher-lactam pyrazolidinone antibacterial agent.
    (Rac)-LY193239
  • HY-120690
    RO5464466 1399767-47-5 98%
    RO5464466 is an hemagglutinin (HA) inhibitor of influenza H1N1 viruses. RO5464466 inhibits HA-mediated hemolysis of chicken erythrocytes with the IC50 of 0.29 μM.
    RO5464466
  • HY-120712
    Ro 31-8588 141979-04-6 98%
    Ro 31-8588 is a HIV protease inhibitor with the Ki of 0.3 nM. Ro 31-8588 can be used for study of AIDS.
    Ro 31-8588
  • HY-120713
    MK-8325 dihydrochloride 1334314-19-0 98%
    MK-8325 (dihydrochloride) is an inhibitor of HCV NS5A with oral activity. MK-8325 exhibits minimal inhibition on hERG at the concentration of 30 mM.
    MK-8325 dihydrochloride
  • HY-120729
    Pyrazophos 13457-18-6 98%
    Pyrazophos (Curamil) is a slightly systemic fungicide against the powdery mildew on crops and cereals. Pyrazophos is widely used in Greece to control diseases caused by Erysiphe spp., Sphaerotheca spp., Leveillula spp. and Oidium spp..
    Pyrazophos
  • HY-120737
    L-702007 139547-89-0 98%
    L-702007 is a potent HIV-1 reverse transcriptase inhibitor.
    L-702007
  • HY-120747
    A-65282 135906-72-8 98%
    A-65282 is an antibacterial agent. A-65282 inhibits P4 DNA unknotting with an IC50 value of 8 µg/mL. A 65281 induces DNA breakage mediated by calf thymus topoisomerase II.
    A-65282
Cat. No. Product Name / Synonyms Application Reactivity