2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-119337
    CE-2072 208840-22-6 98%
    CE-2072 is an inhibitor of serine proteases neutrophil elastase and proteinase-3. CE-2072 inhibits HIV-1 production and p24 production in response to IL-18 or NaCl in infected U1 monocytic cells, reduces virus replication in infected peripheral blood mononuclear cells and blocks infection of permissive HeLa cells. CE-2072 suppresses activation of the HIV-1-inducing transcription factor NF-kB in U1 cells. CE-2072 is promising for research of HIV-1-related disease.
    CE-2072
  • HY-119387
    Chevalone B 1318025-75-0 98%
    Chevalone B was isolated from the ethyl acetate extract of the marine sponge-associated fungus Aspergillus similanensis. The structure of Chevalone B was confirmed by 1D and 2D NMR spectroscopy. Chevalone B showed antimicrobial activity against Gram-positive and Gram-negative bacteria, Candida albicans, and multidrug-resistant strains from the environment. Studies on Chevalone B have shown its potential value in antimicrobial applications.
    Chevalone B
  • HY-119528
    Mansonone F 5090-88-0 98%
    Mansonone F is a potent anti-MRSA sesquiterpenoid quinone that can be found in Thespesia populnea.
    Mansonone F
  • HY-119550
    J1075 383892-69-1 98%
    J1075 is a selective Schistosoma mansoni HDAC8 inhibitor (with decreased affinity for human HDAC8). J1075 can induce apoptosis (Apoptosis) and death in schistosome cells. J1075 holds research value in the field of anti-parasitic agents.
    J1075
  • HY-119556
    Butonate 126-22-7 98%
    Butonate is an insecticide. Butonate is an orally active anthelmintic.
    Butonate
  • HY-119613
    Clociguanil 3378-93-6 98%
    Clociguanil (BRL 50216), a DHFR inhibitor (IC50: 55.6 nM), is an antimalarial agent. Clociguanil has sympathomimetic and antiarrhythmic action.
    Clociguanil
  • HY-119626
    Dihydrodaunomycin 28008-55-1 98%
    Dihydrodaunomycin has antibacterial and antitumor activities.
    Dihydrodaunomycin
  • HY-119648
    CCR-11 1287652-03-2 98%
    CCR-11 is an antibacterial agent. CCR-11 can inhibit the proliferation of B. subtilis cells with an IC50 value of 1.2 μM. CCR-11 inhibits HeLa cell proliferation with an IC50 value of 18.1 μM. CCR-11 inhibits bacterial cytokinesis by inhibiting FtsZ assembly. CCR-11 can be used for the research of FtsZ-targeted antibacterial agents.
    CCR-11
  • HY-119675
    Albonoursin 1222-90-8 98%
    Albonoursin, a microbial secondary metabolite, is an antibacterial peptide. Albonoursin displays antibacterial and antitumor activities.
    Albonoursin
  • HY-119702
    YZ51 1835652-66-8 98%
    YZ51 is a derivative of Osalmid (HY-B2116) with stronger ribonucleotide reductase (RR) inhibitory activity and HBV replication inhibition ability than Osalmid. The IC50 of YZ51 against recombinant RR activity is 0.6 μM, and the IC50 against HepG2.2.15 cell RR activity is 23.7 μM.
    YZ51
  • HY-119707
    TDR 32750 1428183-45-2 98%
    TDR 32750 is an antimalarial agent. TDR 32750 inhibits P. falciparum activity with an ED50 value of 0.014 μM.
    TDR 32750
  • HY-119725
    Tetradifon 116-29-0 99.71%
    Tetradifon is a broad-spectrum organochlorine insecticide and an inhibitor of the mitochondrial oligomycin sensitivity conferring protein (OSCP), which can be used to control a variety of mites. Tetradifon inhibits energy-related activities such as ADP-stimulated respiration, DNP and Mg2+-stimulated ATPase, with an IC50 of 4.5-27 nmoL/mg mitochondrial protein. Tetradifon exerts oligomycin-like activity by inhibiting the oxidative phosphorylation process, inducing oxidative stress and interfering with bone metabolism. Tetradifon is currently mainly used in the research of mitochondrial function regulation, bone remodeling mechanism and nephrotoxicity of environmental pollutants.
    Tetradifon
  • HY-119830
    Azaconazole 60207-31-0 98%
    Azaconazole is an agriculture fungicide, and can be used for controlling powdery mildew on crops and bean rust.
    Azaconazole
  • HY-119839
    Acediasulfone 80-03-5 98%
    Acediasulfone is an antimicrobial. Acediasulfone can formation of a colored product reaction with p-dimethylaminobenzaldehyde.
    Acediasulfone
  • HY-119853
    Bayer A 139 800-24-8 98%
    Bayer A 139 is an ethylene-menaquinone that inactivates fowl plaque virus activity. Bayer A 139 can react with nucleic acids at pH ≦ 7.
    Bayer A 139
  • HY-119898
    Alloocimene 673-84-7 98%
    Alloocimene is a diterpenoid that activates defense genes and induces resistance to Botrytis cinerea in Arabidopsis thaliana.
    Alloocimene
  • HY-119968
    Granaticin 19879-06-2 98%
    Granaticin A inhibits the initial stage of RNA biosynthesis, has anti-Gram-positive bacteria, Mycobacterium (weak) and Vaginal trichomonas activity, but also can inhibit tumor cells.
    Granaticin
  • HY-120002
    Proclonol 14088-71-2 98%
    Proclonol (Kilacar) is an insecticide-acaricide. Proclonol is a weak mutagen in the TA97 strain of S. typhimurium.
    Proclonol
  • HY-120009
    Showdomycin 16755-07-0 98%
    Showdomycin is an antibiotic produced by IM-2-induced in Streptomyces.
    Showdomycin
  • HY-120138
    BDM31827 1388658-04-5 98%
    BDM31827 is an EthR inhibitor. BDM31827 can be used for multidrug-resistant-tuberculosis research.
    BDM31827
Cat. No. Product Name / Synonyms Application Reactivity