2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-116060
    RK-286D 140429-37-4 98%
    RK-286D is an antibiotic and a PKC inhibitor with antimicrobial activity. RK-286D shows inhibitory activities against bleb formation induced by PDBu (HY-18985) and in vitro PKC activity.
    RK-286D
  • HY-116102
    Laurinterol 10539-87-4 98%
    Laurinterol is a Na+/K+-ATPase sodium-potassium ion pump inhibitor that can be isolated from Laurencia johnstonii eliminates.
    Laurinterol
  • HY-116168
    Aldecalmycin 139953-58-5 98%
    Aldecalmycin is an antibiotic showing antimicrobial activities against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MICs values of 6.25-25 μg/mL.
    Aldecalmycin
  • HY-116231
    (S)-Gyramide A 1000592-48-2 98%
    (S)-Gyramide A is a weak inhibitor of cell proliferation that can target DNA gyrase.
    (S)-Gyramide A
  • HY-116251
    CID21480113 1648-34-6 98%
    CID21480113 is an inhibitor of dapsone-resistant leprosy.
    CID21480113
  • HY-116252
    (±)-trans-Lamivudine 131086-22-1 98%
    (±)-trans-Lamivudine is separated from the salt of (S)-(+) mandelic acid. (±)-trans-Lamivudine forms cocrystals with (S)-BINOL. (±)-trans-Lamivudine is promising for research of human immunodeficiency virus infection.
    (±)-trans-Lamivudine
  • HY-116271
    Sperabillin C 111337-84-9 98%
    Sperabillin C is an antibacterial antibiotic with activity against both Gram-negative and Gram-positive bacteria, including resistant strains of Pseudomonas aeruginosa and Staphylococcus aureus.
    Sperabillin C
  • HY-116272
    A51493A 121245-06-5 98%
    A51493A is an anthracyclinone antibiotic with antimicrobial activities against Gram-positive bacteria.
    A51493A
  • HY-116469
    ZP7 1188890-60-9 98%
    ZP7 (compound 7c) is a potent anti-HIV-1 agent with an EC50 of 36.4nM. ZP7 can be utilized in HIV-1 research.
    ZP7
  • HY-116486
    Aureusimine B 170713-71-0 98%
    Aureusimine B (Phevalin) is a cyclic dipeptide. Aureusimine B can be produced by Staphylococcus aureus biofilms. Aureusimine B may be exploited as potential biomarker and/or therapeutic target for chronic, S. aureus biofilm-based infections.
    Aureusimine B
  • HY-116498
    Penigequinolone A 180045-91-4 98%
    Penigequinolone A is an alkaloid isolated from Penicillium. It is lethal to P. penetrans (LD50=100 mg/L) but has no effect on C. elegans at concentrations up to 1000 mg/L.1 Penigequinolone A also accelerates the root growth of rice seedlings in a dose-dependent manner.
    Penigequinolone A
  • HY-116519
    LY173013 126165-78-4 98%
    LY173013 is an antibacterial agent with a broad spectrum antibacterial activity. LY173013 binds to PBP 3 of E.coli and can be utilized in antibacterial research.
    LY173013
  • HY-116552
    KAR425 1809050-49-4 98%
    KAR425 is a potent and orally active antimalarial agent. KAR425 shows antimalarial activity against the Chloroquine-sensitive (CQS) D6, the Chloroquine-resistant (CQR) Dd2, and 7G8 strains of Plasmodium falciparum, with IC50 values of 62 nM, 55 nM, and 60 nM, respectively.
    KAR425
  • HY-116571
    RU44790 110012-78-7 98%
    RU44790 is a monocyclic beta-lactam antibiotic that exerts potent activity against gram-negative bacteria and is highly resistant to hydrolysis by various beta-lactamases. RU44790 can be utilized in anti-bacteria research.
    RU44790
  • HY-116582
    8-Nitroguanine 168701-80-2 98%
    8-Nitroguanine, a product of nitrative DNA damage caused by reactive nitrogen species, is a potential biomarker for progression of malignant fibrous histiocytoma.
    8-Nitroguanine
  • HY-116598
    Lanopepden mesylate 1441390-17-5 98%
    Lanopepden mesylate (GSK 1322322 mesylate) is a peptide deformase (PDF) inhibitor. Lanopepden mesylate has antibacterial activity by inhibiting the activity of PDF, preventing the correct synthesis of bacterial proteins. Lanopepden mesylate mainly targets Gram-positive bacteria. Lanopepden mesylate can be used in the study of acute bacterial skin and skin structural infections.
    Lanopepden mesylate
  • HY-116607
    BAY38-7690 246872-58-2 98%
    BAY38-7690 is a non-nucleoside inhibitor that inhibits HBV replication. BAY38-7690 inhibits viral DNA replication by preventing the formation of viral core particles (nucleocapsids). The IC50 value of BAY38-7690 against HBV in stably transfected HepG2.2.15 cells is 0.15 μM.
    BAY38-7690
  • HY-116631
    Sarisan 18607-93-7
    Sarisan (Asaricin) is a phenolic derivative with antifungal and insecticidal activity. Sarisan can be found in the stem bark of Ocotea opifera Mart..
    Sarisan
  • HY-116686
    Inz-1 897776-15-7 98%
    Inz-1 is a potent and selective mitochondrial cytochrome bc1 inhibitor for yeast (IC50=8.092 μM) over humans (IC50=45.320 μM). Inz-1 reverses Fluconazole (HY-B0101) or other triazole antifungals’ resistance in the pathogenic fungus Candida albicans.
    Inz-1
  • HY-116693
    DprE1-IN-12 634167-64-9 98%
    DprE1-IN-12 (compound 377790) is a covalent and DprE1 inhibitors and shows great activity against M. tuberculosis with an IC50 of 0.5 μM.
    DprE1-IN-12
Cat. No. Product Name / Synonyms Application Reactivity