2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-114763
    LP8 327042-42-2 98%
    LP8 is a Pyridinyl-type CYP51 inhibitor and can be used for study of chagas disease and American trypanosomiasis.
    LP8
  • HY-114881
    Frequentin 29119-03-7 98%
    Frequentin, a secondary metabolite produced by Penicillium janthinellum, is influenced by environmental conditions such as cadmium nitrate and sodium chloride concentrations. In cadmium nitrate-free medium, P. janthinellum produces cyclopenin, carlosic acid, erythroskyrin, kojic acid, and patulin. At 100 ppm cadmium nitrate, it produces cyclopenin, carlosic acid, frequentin, and islandicin. In the presence of sodium chloride, frequentin is produced at 2% and 3% concentrations. These findings indicate that frequentin production is sensitive to specific environmental stressors, highlighting its potential variability under different growth conditions.
    Frequentin
  • HY-114909
    TachypleginA 331839-29-3 98%
    TachypleginA can inhibit the motility of T. gondii by binding directly and covalently to C58 of TgMLC1，thereby causing a decrease in the activity of the parasite's myosin motor.
    TachypleginA
  • HY-114913
    Fenarimol 60168-88-9 98%
    Fenarimol (EL 222) is a potent and orally active fungicide. Fenarimol also is a androgen receptor inhibitor with an IC50 value of 19 µM. Fenarimol decreases the mRNA expression of PBP C3, ODC, IGF-1.
    Fenarimol
  • HY-114927
    (±)-Dunnione 521-49-3 98%
    (±)-Dunnione (SL 11010) is a compound with broad-spectrum antifungal activity that acts by initiating redox cycling.
    (±)-Dunnione
  • HY-115127
    3-Methylanisole 100-84-5 99.42%
    3-Methylanisole is an intermediate in drug synthesis, which has antiseptic, antibacterial and protein stabilizing effects.
    3-Methylanisole
  • HY-115159
    Ro 14-9578 100891-41-6 98%
    Ro 14-9578 is a tricyclic quinolone analog with antibacterial activity. Ro 14-9578 inhibits DNA biosynthesis (IC50=117 μM) and DNA supercoiling (IC50=66.8 μM) in Escherichia coli. Furthermore, Ro 14-9578 exhibits inhibitory effects against various Gram-negative bacteria and Staphylococcus aureus.
    Ro 14-9578
  • HY-115407
    Cochliodone A 1072931-48-6 98%
    Cochliodone A is an active compound extracted from cultures of the deep-sea derived fungus Chaetomium sp. and has antibacterial and anticancer activity. Cochliodone A is toxic to a variety of bacteria, with MICs of 15.3 μg/mL (V. vulnificus), 32.7 μg/mL (V. rotiferianus), 15.9 μg/mL (S. aureus ATCC 43300), and 16.3 μg/mL (S . aureus CGMCC 1.12409). Cochliodone A also inhibits a variety of cancer cell lines, with IC50s of 28.1 μM (A549), 20.7 μM (HeLa), and 23.2 μM (Hep G2).
    Cochliodone A
  • HY-115430
    Tenofovir disoproxil aspartate 1571075-19-8 98%
    Tenofovir disoproxil aspartate is a nucleotide reverse transcriptase inhibitor used to treat HIV and chronic Hepatitis B.
    Tenofovir disoproxil aspartate
  • HY-115441
    (Rac)-Luliconazole 101530-21-6 98%
    (Rac)-Luliconazole ((Rac)-NND 502) is the racemic isomer of Luliconazole (HY-14283). Luliconazole is a topical antifungal imidazole antibiotic with broad-spectrum and potent antifungal activity.
    (Rac)-Luliconazole
  • HY-115513
    Pitstop 1 1332879-51-2 98%
    Pitstop 1 is a small molecule inhibitor with endocytosis-inhibiting activity. Pitstop 1 blocks the interaction of chaperones with the Krasin terminal domain in cells, thereby affecting the function of Krasin. Pitstop 1 exhibits superior biological activity in significantly inhibiting the effects of Krasin. Pitstop 1 acts as a dose that inhibits the entry of viruses and pathogens into cells and modulates cell signaling.
    Pitstop 1
  • HY-115693
    CAP 3 2292123-03-4 98%
    CAP 3 is a cholic acid-peptide conjugate (CAP) antimicrobial agent. CAP 3 effectively inhibits Gram-negative bacteria, with MIC99 (minimum inhibitory concentration for 99% bacterial killing) values of 8 μM, 16 μM, and 16 μM against E. coli, Klebsiella pneumoniae and Acinetobacter baumannii, respectively. CAP 3 exerts its antibacterial effects by disrupting the structural integrity of the bacterial lipopolysaccharide (LPS) outer membrane. CAP 3 rapidly kills bacteria, inhibits biofilm formation, and effectively combats drug-resistant strains and persistent bacterial infections.
    CAP 3
  • HY-115805
    YKL-04-085 2120356-29-6 98%
    YKL-04-085 is potent inhibitors of viral translation, with an IC90 of 0.555 μM for DENV2. YKL-04-085 is devoid of any kinase activity.
    YKL-04-085
  • HY-115843
    LL-D05139β 95153-19-8 98%
    LL-D05139β is a potent antibacterial antibiotic and antitumor agent.
    LL-D05139β
  • HY-115845
    ML366 851094-56-9 98%
    ML366 is an inhibitor of Vibrio cholerae Quorum Sensing, exhibiting activity by targeting the LuxO response regulator.
    ML366
  • HY-115848
    Antiviral agent 12 314030-54-1 98%
    Antiviral agent 12 is a antiviral compound. Antiviral agent 12 inhibits Ebola virus entry into host cells by binding to surface glycoprotein, EC50 is 3.9 μM. Antiviral agent 12 can be used in the study of Ebola virus.
    Antiviral agent 12
  • HY-115859
    SCH 25393 73212-54-1 98%
    SCH 25393 is a potent antibacterial agent.
    SCH 25393
  • HY-116004
    Anti-Trypanosoma cruzi agent-5 205381-53-9 98%
    Anti-Trypanosoma cruzi agent-5 (compoung 8) is a potent inhibitor of Trypanosoma cruzi proliferation.
    Anti-Trypanosoma cruzi agent-5
  • HY-116021
    Buquinolate 5486-03-3 98%
    Buquinolate is a quinoline derivative. Buquinolate is effective in preventing coccidiosis of chickens.
    Buquinolate
  • HY-116034
    Arasertaconazole 583057-48-1 98%
    Arasertaconazole is a potent 14α-lanosterol demethylase inhibitor. Arasertaconazole has antifungal and antibacterial activity.
    Arasertaconazole
Cat. No. Product Name / Synonyms Application Reactivity