2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-10980R
    Tavaborole (Standard) 174671-46-6
    Tavaborole (Standard) is the analytical standard of Tavaborole. This product is intended for research and analytical applications. Tavaborole (AN-2690) is an antifungal agent with activity against Trichophyton species, in a topical solution formulation for the potential treatment of onychomycosis.
    Tavaborole (Standard)
  • HY-110038
    FTI-277 TFA 1217447-06-7 98%
    FTI-277 TFA is an inhibitor of farnesyl transferase (FTase); a highly potent Ras CAAX peptidomimetic which antagonizes both H- and K-Ras oncogenic signaling. FTI-277 TFA can inhibit hepatitis delta virus (HDV) infection.
    FTI-277 TFA
  • HY-110061
    (2R,4R,6S)-Tubacin 1350555-93-9 98%
    (2R,4R,6S)-Tubacin is the 2R,4R,6S enantiomer of Tubacin (HY-13428). Tubacin is a potent and selective inhibitor of HDAC6, with an IC50 value of 4 nM and approximately 350-fold selectivity over HDAC1. Tubacin also inhibits metallo-β-lactamase domain-containing protein 2 (MBLAC2).
    (2R,4R,6S)-Tubacin
  • HY-110082
    Quinine hydrochloride 130-89-2 98%
    Quinine (hydrochloride) is an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine (hydrochloride) is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV with an IC50 of 169 μM.
    Quinine hydrochloride
  • HY-110093
    UNC0638 hydrate 1255517-77-1 98%
    UNC0638 hydrate selectively inhibits G9a and GLP histone methyltransferases with IC50 of 15 nM and 19 nM, respectively. UNC0638 hydrate inhibits TNBC cell invasion and migration in vitro. UNC0638 hydrate is also an inhibitor of EHMT1/2 and induces fetal hemoglobin (HbF) expression in human erythroid progenitor cell culture. In addition, UNC0638 hydrate has anti-FMDV (foot-and-mouth disease virus) and anti-VSV (vesicular stomatitis virus) activities, with excellent potency and selectivity against multiple epigenetic and non-epigenetic targets.
    UNC0638 hydrate
  • HY-111026
    PPQ-581 950381-32-5 98%
    PPQ-581 is an anti-influenza agent with an EC50 of 1 μM for preventing virus-induced cytopathic effects. PPQ-581 inhibits viral protein synthesis. PPQ-581 blocks the RNP nuclear export and cytoplasmic RNP aggregation.
    PPQ-581
  • HY-111028
    J1038 949727-86-0 98%
    J1038 (T 5979345) is a selective HDAC8 inhibitor. J1038 binds the catalytic zinc ion of Schistosoma mansoni HDAC8 (smHDAC8).
    J1038
  • HY-111074
    DB12055 934017-32-0 98%
    DB12055 (MK-0767 analog) is a covalent SARS-CoV-2 3CL protease inhibitor. DB12055 has the potential for the study of dyslipidemia and diabetes mellitus.
    DB12055
  • HY-111154
    BPH-608 911783-02-3 98%
    BPH-608 is a bacterial undecenyl diphosphate synthase (UPPS) inhibitor (IC50=590 nM) with antibacterial activity.
    BPH-608
  • HY-111190
    Thiotropocin 89550-93-6 98%
    Thiotropocin is a tropothione Antibiotic with antibacterial activities against Gram-positive and Gram-negative bacteria, some phytopathogens and mycoplasma. Thiotropocin causes morphological changes of Proteus mirabilis and Escherichia coli.
    Thiotropocin
  • HY-111222
    PD 113270 87860-37-5 98%
    PD 113270 (CL 1565-B) is an antitumor agent. PD 113270 exhibits inhibitory effects to yeasts.
    PD 113270
  • HY-111264
    Naphthomycin B 86825-88-9 98%
    Naphthomycin B is an antibiotic, which is initially isolated from Streptomyces sp. Naphthomycin B exhibits antimicrobial activities against gram positive bacteria and many fungis.
    Naphthomycin B
  • HY-111279
    Sisapronil 856225-89-3 98%
    Sisapronil is a phenylpyrazole ectoparasiticide, that is widely used in the veterinary field.
    Sisapronil
  • HY-111801
    Woodorien 155112-92-8 98%
    Woodorien is a potent HSV-1 inhibitor. Woodorien also is a glucoside that can be isolated from Woodwardia orientalis.
    Woodorien
  • HY-113557
    DNAC-1 1006021-30-2 98%
    DNAC-1 is a potent antibacterial agent. DNAC-1 enhances β-lactam activity against Gram positive and Gram negative pathogens.
    DNAC-1
  • HY-113561
    Biphenomycin A 100296-21-7 98%
    Biphenomycin A (LL-AF283α) is a cyclic peptide antibiotic that can be found in Streptomyces griseorubiginosus 43708. It has antibacterial activity and can be used in research in the field of anti-infection.
    Biphenomycin A
  • HY-113562
    Laidlomycin phenylcarbamate 101191-83-7 98%
    Laidlomycin phenylcarbamate is a semisynthetic polyether antibiotic with antiparasitic activity.
    Laidlomycin phenylcarbamate
  • HY-113569
    Armentomycin 10139-00-1 98%
    Armentomycin (L-Armentomycin) is a nonprotein amino acid with antibiotic properties. Armentomycin mainly acts against Gram-negative bacteria.
    Armentomycin
  • HY-113582
    Albothricin 103867-06-7 98%
    Albothricin is a potent streptothricin Antibiotic with antimicrobial activities.
    Albothricin
  • HY-113586
    Besifovir Dipivoxil 441785-26-8 98%
    Besifovir Dipivoxil (LB-80380), an analog of guanosine monophosphate, is an acyclic nucleotide phosphonate with antiviral effect. Besifovir Dipivoxil is rapidly converted by the liver and intestine to the intermediate metabolite LB80331 via the esterification process, subsequently phosphorylated into the di- and triphosphate forms, which act as antiviral DNA synthesis inhibitors. Besifovir Dipivoxil is promising for research of chronic hepatitis B.
    Besifovir Dipivoxil
Cat. No. Product Name / Synonyms Application Reactivity