2. Endocrinology

Endocrinology

Endocrinology

Related Products

PDF 21.44 MB

Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-118465
    ent-Prostaglandin E2 65085-69-0 98%
    ent-Prostaglandin E2 (ent-PGE2) is an enantiomer of PGE2 (HY-101952). unlike PGE2, ent-PGE2 is a poor substrate for 15-hydroxyprostaglandin dehydrogenase.
    ent-Prostaglandin E2
  • HY-118499
    Alpiropride 81982-32-3 98%
    Alpiropride (RIV-2093) is a metoclopramide (HY-17382) analog that is effective in reducing the gastrointestinal side effects of cancer chemotherapy drugs. In animal studies, alpiropride showed a stronger antiemetic effect than metoclopramide.
    Alpiropride
  • HY-118534
    Cyclobutyrol 512-16-3 98%
    Cyclobutyrol is a potent choleretic agent. Cyclobutyrol also inhibits biliary lipid secretion. Cyclobutyrol induces choleretic is unrelated to bile acids. Cyclobutyrol and bile acids do not compete for the hepatobiliar transport mechanisms[1]
    Cyclobutyrol
  • HY-118548
    Tetranor-PGAM 52510-53-9 98%
    Tetranor-PGAM is a tetranor-prostaglandin A metabolite. Tetranor-PGAM is a dehydration product of tetranor-PGEM (HY-114988). Tetranor-PGAM can be measured as a surrogate for tetranor-PGEM levels in urine.
    Tetranor-PGAM
  • HY-118556
    Prostaglandin E2 serinol amide 951209-67-9 98%
    Prostaglandin E2 serinol amide is a weak inhibitor of the hydrolysis of [3H]2-oleoylglycerol. Prostaglandin E2 serinol amide is non-hydrolyzable to produce PGE2 and thus cannot inhibit leukotriene B4 biosynthesis, superoxide production, migration and antimicrobial peptide release.
    Prostaglandin E2 serinol amide
  • HY-118633
    Ethamoxytriphetol 67-98-1 98%
    Ethamoxytriphetol (MER-25) is a nonsteroidal antiestrogen.
    Ethamoxytriphetol
  • HY-118772
    17-Phenyl trinor prostaglandin A2 38315-51-4 98%
    17-Phenyl trinor prostaglandin A2 is a synthetic prostaglandin analog.
    17-Phenyl trinor prostaglandin A2
  • HY-118861
    Enclomiphene 15690-57-0 98%
    Enclomiphene ((E)-Clomiphene) is a potent and orally active non-steroidal estrogen receptor antagonist, with antioestrogenic property. Enclomiphene can be used for the research of ovarian dysfunction, testosterone deficiency, male hypogonadism and type 2 diabetes.
    Enclomiphene
  • HY-118950
    J 628 65323-80-0 98%
    J 628 is an estrogen derivative used to study antifertility effects after sexual intercourse in mice, rats, and rabbits.
    J 628
  • HY-118978
    PF-00277343 332926-04-2 98%
    PF-00277343 is a selective and skin-penetrable THR-β (Ki: 0.51 nM for THR-β, 8.0 nM for THR-α) agonist. PF-00277343 is effective against androgenetic alopecia in animal models.
    PF-00277343
  • HY-119006
    L-640,033 115326-36-8 98%
    L-640,033 is a potent agonist of β-adrenergic. L-640,033 play an important role in lipid metabolism, and growth.
    L-640,033
  • HY-119095
    L-741671 187724-85-2 98%
    L-741671 is a selective and brain-permeable antagonist of neurokininl (hNKI) receptor, with Kis of 64 nM, 0.03 nM and 0.7 nM in rat, human and ferret, respectively.
    L-741671
  • HY-119332
    3-Keto petromyzonol 359436-56-9 98%
    3-Keto petromyzonol, a main component of Sea lamprey male sex pheromones, modulates both synthesis and release of gonadotropin releasing hormone (GnRH), and subsequently, hypothalamic-pituitary-gonadal (HPG) output in immature sea lamprey.
    3-Keto petromyzonol
  • HY-119539
    Limocitrin 489-33-8 98%
    Limocitrin is a natural product that can be isolated from the buds of P. acerifolia and P. orientalis. Limocitrin suppresses estradiol-dependent proliferation of MCF7 cells weakly but estradiol-induced AlkP (alkaline phosphatase) expression only marginally.
    Limocitrin
  • HY-119611
    Thioquinapiperifil 220060-39-9 98%
    Thioquinapiperifil (KF31327 free base), a potent, selective and non-competitive phosphodiesterase-5 (PDE-5, IC50 of 0.074 nM) inhibitor, is used for sexual enhancement study.
    Thioquinapiperifil
  • HY-119615
    Mezilamine 50335-55-2 98%
    Mezilamine is a potent antidopaminergic agent. Mezilamine induces a concentration dependent increase in the electrically stimulated overflow of 3H-noradrenaline from rat cortical slices, without affecting the basal overflow. Mezilamine acts as a presynaptic α-adrenoceptor antagonist and a postsynaptic α-adrenoceptor agonist.
    Mezilamine
  • HY-120197
    17-Phenyl trinor prostaglandin F2α methyl amide 155206-01-2 98%
    17-Phenyl trinor prostaglandin F2α methyl amide is a prostaglandin F 2α (PGF 2α) analog that competes with native PGF 2α for receptor binding.
    17-Phenyl trinor prostaglandin F2α methyl amide
  • HY-120285
    M-0002 hydrochloride 285559-03-7 98%
    M-0002 hydrochloride (RWJ-351647 hydrochloride) is a biologically active compound that acts as an antagonist of the vasopressin V2 receptor. M-0002 hydrochloride is potentially useful for inhibiting ascites. M-0002 hydrochloride shows excellent properties that are favorable for clinical development.
    M-0002 hydrochloride
  • HY-120287
    L-054522 214348-67-1 98%
    L-054522 is an agonist for somatostatin receptor subtype 2 with Kd of 0.01 nM. L-054522 inhibits growth hormone release from rat primary pituitary cell (IC50=0.05 nM) and glucagon and insulin release from isolated mouse pancreatic islet cell (IC50=0.05 nM and 12 nM).
    L-054522
  • HY-120301
    L-366682 127819-96-9 98%
    L-366682, a cyclic hexapeptide, possesses antagonism of oxytocin.
    L-366682
Cat. No. Product Name / Synonyms Application Reactivity