2. Endocrinology

Endocrinology

Endocrinology

Related Products

PDF 21.44 MB

Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B1001
    Todralazine 14679-73-3 98%
    Todralazine (Ecarazine) is an anti-hypertensive agent, acts as a β2AR blocker, with antioxidant and free radical scavenging activity.
    Todralazine
  • HY-B1034
    Vanitiolide 17692-71-6 98%
    Vanitiolide is a cholagogue.
    Vanitiolide
  • HY-B1617
    Zuclomiphene 15690-55-8 98%
    Zuclomiphene is a cis isomer of Clomiphene citrate (HY-B0463). Zuclomiphene is orally active and has an antiestrogenic effect. Zuclomiphene can reduce cholesterol levels. Zuclomiphene can be for the researches of endocrinology and metabolic disease.
    Zuclomiphene
  • HY-B1711
    Norfenefrine 536-21-0
    Norfenefrine is an orally active, endogenously found α-adrenergic agonist and can be used for the research of female stress incontinence.
    Norfenefrine
  • HY-B1951
    Trietazine 1912-26-1 98%
    Trietazine is a selective pre- and post-emergence glyphosate-based herbicide. Trietazine residues cause human health risks, such as cancer, birth defects, and hormone imbalance.
    Trietazine
  • HY-D2379
    HMRG 1629965-68-9 98%
    HMRG is a type of hydroxymethyl rhodamine green fluorescent scaffold, featuring an open non-cyclic structure. HMRG can produce significant dynamic fluorescence changes through a one-step enzymatic reaction at physiological pH, which is useful for developing various probes. Fluorescent probes based on HMRG can be used for fluorescence detection of diseases such as tumors and diabetic nephropathy.
    HMRG
  • HY-N3101
    Pedalitin 22384-63-0 98%
    Pedalitin is a inhibitor of tyrosinase（IC50=0.28 mM） and α-glucosidase（IC50=0.29 mM）.
    Pedalitin
  • HY-N3257
    Millewanin G 874303-33-0 98%
    Millewanin G is a prenylated isoflavonoid with antiestrogenic activity (IC50=29 μM). Millewanin G can be isolated from the leaves of M. pachycarpa cultivated in Japan.
    Millewanin G
  • HY-N3503
    Ganoderlactone D 1801934-15-5 99.0%
    Ganoderlactone D shows inhibitory effects of yeast α-Glucosidase with IC50 values of 41.7 μM.
    Ganoderlactone D
  • HY-N5103
    Genistein 7,4'-di-O-β-D-glucoside 36190-98-4 98%
    Genistein 7,4'-di-O-β-D-glucoside is a natural product with significantly estrogenic proliferative effect in MCF-7 cells.
    Genistein 7,4'-di-O-β-D-glucoside
  • HY-N6181
    Terrelumamide A 1802497-05-7 98%
    Terrelumamide A is a lumazine-containing peptide. Terrelumamide A is isolated from the culture broth of the marine-derived fungus Aspergillus terreus. Terrelumamide A exhibits pharmacological activity by improving insulin sensitivity. Terrelumamide A has the potential in the application of DNA sequence recognition.
    Terrelumamide A
  • HY-N7241
    Saudin 94978-16-2 98%
    Saudin, derived from Clutia lanceolata, is a hypoglycemic compound that significantly enhances glucose-triggered insulin release from murine pancreatic islets. It belongs to a group of new diterpenoids with a distinct tetracyclic core, suggesting potential as a therapeutic agent for diabetes treatment. Proposed biosynthetic pathways outline alternative cyclization routes from a common precursor, with Lanceolide P (16) identified as a promising lead compound for further development in managing diabetes.
    Saudin
  • HY-N8170
    4',2-Dihydroxy-4,6-dimethoxydihydrochalcone 151752-07-7 98%
    4',2-Dihydroxy-4,6-dimethoxydihydrochalcone, an estrogen agonist, shows binding affinity for bovine uterine estrogen receptor with an IC5050 of 15 μM.
    4',2-Dihydroxy-4,6-dimethoxydihydrochalcone
  • HY-N8550
    Cortolone 516-42-7 98%
    Cortolone (α-Cortolone) is a metabolite of the glucocorticoid cortisol (Hydrocortisone (HY-N0583)). Hydrocortisone is a steroid hormone or glucocorticoid secreted by the adrenal cortex.
    Cortolone
  • HY-NP180
    Progesterone/BSA
    Progesterone/BSA is a conjugate of Progesterone (HY-N0437) and bovine serum albumin. Progesterone/BSA has important applications in immunology, diagnostic reagent development and biomedical research.
    Progesterone/BSA
  • HY-P0037
    Org-30850 136208-71-4 98%
    Org-30850 is a potent LHRH antagonist designed for treating hormone-dependent disorders. In animal studies, a single subcutaneous dose effectively inhibited ovulation in rats and significantly reduced testosterone levels in male rats for up to 48 hours post-administration. Daily doses of Org-30850 in female rats suppressed estrous cycles, decreased uterine and ovarian weights, and lowered estradiol and FSH serum levels. In male rats, prolonged treatment resulted in reversible reductions in gonadal function and testosterone levels, with almost complete recovery observed after cessation of treatment. Unlike comparable LHRH antagonists, Org-30850 exhibited minimal injection site irritation and no edematous reactions, suggesting a more favorable therapeutic profile.
    Org-30850
  • HY-P0042
    BIM-23197 168016-90-8 98%
    BIM-23197 is an SST2 (IC50 = 0.19 nM) agonist. BIM-23197 can effectively stimulate intracellular calcium mobilization in cells expressing SST2. BIM-23197 can be used for research on endocrine related conditions.
    BIM-23197
  • HY-P0077
    Merotocin 1190083-57-8 98%
    Merotocin is a selective, short-acting peptidic oxytocin receptor agonist. Merotocin can be used to support lactation.
    Merotocin
  • HY-P0096
    Decapeptide-12 137665-91-9 99.95%
    Decapeptide-12, a small oligopeptide, is a tyrosinase inhibitor that interacts with C-terminal residue of tyrosinase (Kd: 61.1 μM). Decapeptide-12 is a competitive inhibitor of mushroom tyrosinase (IC50: 40 μM). Decapeptide-12 also increases transcription of SIRT. Decapeptide-12 reduces melanin content in melanocytes. Decapeptide-12 is used for the research of melanogenesis, senescence, inflammation .
    Decapeptide-12
  • HY-P0193
    Nocistatin (Bovine) 208253-85-4 98%
    Nocistatin (Bovine) is a nociceptin precursor contains another biologically active peptide. Nocistatin (Bovine) blocks nociception-induced allodynia and hyperalgesia. Nocistatin (Bovine) also attenuates pain evoked by prostaglandin E2. Nocistatin (Bovine) can bind to the membrane of mouse brain and spinal cord with high affinity. Nocistatin (Bovine) can be studied in research on pain transmission.
    Nocistatin (Bovine)
Cat. No. Product Name / Synonyms Application Reactivity