2. Endocrinology

Endocrinology

Endocrinology

Related Products

PDF 21.44 MB

Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-100287
    2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide 137089-36-2 98%
    2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide is a compound that inhibits stress-induced ulcer and low toxicity, and can maintain the content of phospholipase A2 and prostaglandin E2 in ulcerated rats induced by water immersed restrained stress.
    2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide
  • HY-100297
    MK-447 58456-91-0 98%
    MK-447 is a free radical scavenger, also a nonsteroidal antiinflammatory agent, and enhances the formation of the endoperoxide, PGH2, and other prostaglandins.
    MK-447
  • HY-100301
    FR167344 free base 215258-13-2 98%
    FR167344 free base is an orally active, nonpeptide bradykinin receptor B2 antagonist. FR167344 free base shows a high affinity binding to the B2 receptor with an IC50 value of 65 nM and no binding affinity for the B1 receptor.
    FR167344 free base
  • HY-100305
    Substituted piperidines-1 170842-46-3 98%
    Substituted piperidines-1 is a compound that can promote the release of growth hormone in humans and animals.
    Substituted piperidines-1
  • HY-100318
    NGD-4715 476322-70-0 98%
    NGD-4715 is a selective and orally active melanin-concentrating hormone receptor 1 (MCHR1) antagonist .
    NGD-4715
  • HY-10052R
    Aprepitant (Standard) 170729-80-3
    Aprepitant (Standard) is the analytical standard of Aprepitant. This product is intended for research and analytical applications. Aprepitant (MK-0869) is a selective and high-affinity neurokinin 1 receptor antagonist with a Kd of 86 pM.
    Aprepitant (Standard)
  • HY-10053S
    Maropitant-d3 2124295-52-7 98%
    Maropitant-d3 is the deuterium labeled Maropitant. Maropitant is a selective and orally active neurokinin (NK1) receptor antagonist. Maropitant acts by blocking the binding of substance P within the emetic center and the chemoreceptor trigger zone (CRTZ). Maropitant is highly effective in preventing vomiting.
    Maropitant-d3
  • HY-100571
    Cloprostenol isopropyl ester 157283-66-4 98%
    Cloprostenol isopropyl ester, a prostaglandin F2α analogs, is the intermediate of (+)-Cloprostenol (HY-107381). Cloprostenol isopropyl ester is a FP receptor agonist with a Ki value of 28 nM.
    Cloprostenol isopropyl ester
  • HY-100607
    Landiolol 133242-30-5 98%
    Landiolol (ONO1101) is a highly selective, ultra-short-acting competitive inhibitor of β1 adrenergic receptors. Landiolol specifically blocks cardiac β1 receptors, reducing heart rate and myocardial oxygen consumption. Landiolol inhibits TNF-α-induced excessive mitochondrial oxygen consumption and reactive oxygen species production in a sepsis model, alleviating renal injury. Landiolol has little effect on cardiac ion channels (such as L-type calcium current and inward rectifier potassium current) and has a weak negative inotropic effect. Landiolol can be used for perioperative tachycardia control and protection studies of sepsis-related acute kidney injury.
    Landiolol
  • HY-100661
    Cetirizine Impurity D 346451-15-8 98%
    Cetirizine Impurity D is an impurity of Cetirizine. Cetirizine, a second-generation antihistamine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response.
    Cetirizine Impurity D
  • HY-100767
    Guanylyl Imidodiphosphate trisodium 148892-91-5 98%
    Guanylyl Imidodiphosphate (Guanosine 5'-[β,γ-imido]triphosphate) trisodium is a non-hydrolysable GTP analogue, an activator of ADP-ribosylation factor (ARF) and a potent stimulator of adenylate cyclase. Imidodiphosphate trisodium can be used in protein synthesis studies.
    Guanylyl Imidodiphosphate trisodium
  • HY-100934
    SC-9 102649-78-5 98%
    SC-9 is a PKC activator in the presence of Ca2+.
    SC-9
  • HY-100940
    6-Chloromelatonin 63762-74-3 98%
    6-Chloromelatonin is a potent melatonin receptor agonist with greater metabolic stability than melatonin. 6-Chloromelatonin compete for [3H]-melatonin and 2-[125I]-iodomelatonin binding to MT1 receptors (pKi=8.9 and 9.1, respectively). 6-Chloromelatonin compete for [3H]-melatonin binding to MT2 receptors (pKi=9.77).
    6-Chloromelatonin
  • HY-101038
    ZK 756326 874911-96-3 98%
    ZK756326 is a nonpeptide chemokine receptor agonist for the CC chemokine receptor CCR8.
    ZK 756326
  • HY-101236
    ICI 192605 117621-64-4 98%
    ICI 192605 is a potent TXA2R (thromboxane A2 receptor) antagonist as cell signaling prostaglandin. ICI 192605 blocks contraction of isolated guinea pig trachea induced by U-46619.
    ICI 192605
  • HY-101320
    ZD-7114 129689-30-1 98%
    ZD-7114 is a potent and selective agonist of β3-adrenergic. ZD-7114 is a selective thermogenic agent in vivo. ZD-7114 can be used in study obesity and diabetes.
    ZD-7114
  • HY-101602
    Aligeron 70713-45-0 98%
    Aligeron is a non-selective prostaglandin (PG) antagonist, and has vasodilatory properties.
    Aligeron
  • HY-101606
    Etersalate 62992-61-4 98%
    Etersalate inhibits platelet function and decreases thromboxane A2 (TXA2) levels.
    Etersalate
  • HY-101692
    AZ-1355 75451-07-9 98.19%
    AZ-1355 is an orally active and effctive lipid-lowering agent. AZ-1355 inhibits platelet aggregation in vivo and elevates the prostaglandin I2/thromboxane A2 ratio in vitro.
    AZ-1355
  • HY-101752
    (±)-Befunolol 39552-01-7 98%
    (±)-Befunolol is a β-adrenoceptor blocking agent.
    (±)-Befunolol
Cat. No. Product Name / Synonyms Application Reactivity