1. Endocrinology

Endocrinology

Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P4693
    (Ser(tBu)6,Azagly10)-LHRH 184686-52-0 98%
    (Ser(tBu)6,Azagly10)-LHRH is a potent aza-GLY analog.
    (Ser(tBu)6,Azagly10)-LHRH
  • HY-P4696
    pTH (3-34) (bovine) 51257-86-4 98%
    pTH (3-34) (bovine) is apTH ((Human parathyroid hormone) fragment.
    pTH (3-34) (bovine)
  • HY-P4700
    pTH (53-84) (human) 89439-30-5 98%
    pTH (53-84) (human) is apTH ((Human parathyroid hormone) fragment.
    pTH (53-84) (human)
  • HY-P4852
    ACTH (2-24) (human, bovine, rat) 67654-32-4 98%
    ACTH (2-24) (human, bovine, rat) is a peptide analogue of ACTH.
    ACTH (2-24) (human, bovine, rat)
  • HY-P4856
    pTH-Related Protein (1-40) (human, mouse, rat) 120298-73-9 98%
    pTH-Related Protein (1-40) (human, mouse, rat) stimulates calcium uptake in rat intestinal cells through PTHR1 receptor and PKCα signaling pathways. pTH-Related Protein (1-40) up-regulates parathyroid hormone 1 receptor (PTHR1) protein, four transcellular calcium transporters, potential vanillin member 6 (TRPV6), calcium-binding protein-D9K (CaBP-D9k), sodium-calcium Exchanger 1 (NCX1) and plasma membrane calcium ATPase 1 (PMCA1).
    pTH-Related Protein (1-40) (human, mouse, rat)
  • HY-P4857
    pTH-Related Protein (7-34) amide (human, mouse, rat) 115695-30-2 98%
    pTH-Related Protein (7-34) amide (human, mouse, rat) is a potent antagonist of parathyroid hormone (PTH).
    pTH-Related Protein (7-34) amide (human, mouse, rat)
  • HY-P4990
    Pro8-Oxytocin 24327-19-3 98%
    Pro8-Oxytocin is a a modified oxytocin (OXT) ligand. Pro8-Oxytocin produces more potent and efficacious responses at primate OXTR and stronger behavioral effects than the consensus mammalian OXT ligand (Leu8-Oxytocin). Pro8-Oxytocin produce a less efficacious response than Vasopressin (HY-B1811) (AVP) at human AVPR1a and higher efficacious response than AVP at marmoset AVPR1a.
    Pro8-Oxytocin
  • HY-P5017
    (Val3,Pro8)-Oxytocin 2134138-89-7 98%
    (Val3,Pro8)-Oxytocin is the Gq-dependent pathway agonist. (Val3,Pro8)-Oxytocin is also a weaker agonist for the β-arrestin engagement and endocytosis toward the oxytocin receptor (OXTR).
    (Val3,Pro8)-Oxytocin
  • HY-P5214
    Vasopressin Dimer (anti-parallel) (TFA) 98%
    Vasopressin Dimer (anti-parallel) TFA is an anti-parallel dimer of Vasopressin (HY-B1811). Vasopressin Dimer (anti-parallel) TFA can activate four G protein-coupled receptors, V1aR, V1bR, V2R, and OTR.
    Vasopressin Dimer (anti-parallel) (TFA)
  • HY-P5518
    [Des-Arg10]-HOE I40 1054763-33-5 98%
    [Des-Arg10]-HOE I40 is a potent bradykinin B1 receptor antagonist.
    [Des-Arg10]-HOE I40
  • HY-P5523
    iE-DAP 592520-07-5 98%
    iE-DAP is a Nod1 agonist. Nod1 recognition of iE-DAP can activate the NF-κB pathway, leading to an inflammatory cytokine response. iE-DAP can be used for the research of maternal-fetal inflammation and preterm labor.
    iE-DAP
  • HY-P5866
    Allatotropin 120928-88-3 98%
    Allatotropin (Manse-AT) is a 13 amino acid neuropeptide. Allatotropin activates inositol 1,4,5-trisphosphate (IP3) pathway, and the biosynthesis of juvenile hormone (JH) in Manduca sexta.
    Allatotropin
  • HY-P6176
    JLB2-110c 3032608-72-0 98%
    JLB2-110c activates MCRs receptor (mMC4R EC50 = 0.34 nM) and has a strong in vivo appetite suppressant effect.
    JLB2-110c
  • HY-100141
    Ancarolol 75748-50-4 98%
    Ancarolol is a beta-adrenergic blocking agent.
    Ancarolol
  • HY-100150
    Mepixanox 17854-59-0 98%
    Mepixanox (Pimexone) is an analeptic agent used in respiratory and cardiorespiratory insufficiency.
    Mepixanox
  • HY-10017A
    (R)-SCH 546738 2181148-54-7 99.75%
    (R)-SCH 546738 is the R-isomer of SCH 546738 (HY-10017). SCH 546738 is an orally active and non-competitive antagonist for CXCR3 with Ki of 0.4 nM for human CXCR3 receptor.
    (R)-SCH 546738
  • HY-100191
    BMY-25271 78441-82-4 98%
    BMY-25271 is a histamine H2 receptor antagonist.
    BMY-25271
  • HY-100255
    Tiodazosin 66969-81-1 98%
    Tiodazosin is a potent competitive postsynaptic alpha adrenergic receptor antagonist.
    Tiodazosin
  • HY-100261
    CCR5 antagonist 1 716354-86-8 98%
    CCR5 antagonist 1 is a CCR5 antagonist which can inhibit HIV replication extracted from WO 2004054974 A2.
    CCR5 antagonist 1
  • HY-100280
    Pirolate 55149-05-8 98%
    Pirolate is a histamine H1 receptor antagonist.
    Pirolate
Cat. No. Product Name / Synonyms Application Reactivity