2. Endocrinology

Endocrinology

Endocrinology

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Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P4008
    [Deamino-4-valine, 8-D-arginine]-Vasopressin 43157-23-9 98%
    [Deamino-4-valine, 8-D-arginine]-Vasopressin (dVDAVP) is a highly potent and specific antidiuretic agent possessing protracted effects.
    [Deamino-4-valine, 8-D-arginine]-Vasopressin
  • HY-P4012
    [Asu1,6-Arg8]Vasopressin 40944-53-4 98%
    [Asu1,6-Arg8]Vasopressin is an vasopressin agonist which potentiates cyclic AMP accumulation and ACTH release induced by corticotropin-releasing factor (CRF) in rat anterior pituitary cells in culture.
    [Asu1,6-Arg8]Vasopressin
  • HY-P4144
    Onvitrelin ucalontide 1174415-90-7 98%
    Onvitrelin ucalontide ([Phor18-LHRH (338613)]) is an analogue of luteinizing hormone releasing hormone (LHRH) with antineoplastic activity. Onvitrelin ucalontide is a peptide with sequences of KFAKFAKKFAKFAKKFAKQHWSYGLRPG. Onvitrelin ucalontide effectively inhibits breast cancer, ovarian cancer and prostate cancer xenografts in mouse model.
    Onvitrelin ucalontide
  • HY-P4249
    Gly-Gly-Arg 54944-27-3 98%
    Gly-Gly-Arg is a tripeptide, and a “pumping pheromone” released from the hatching eggs. Gly-Gly-Arg induces pleopod pumping activity, with the threshold concentration of 10 nM. Gly-Gly-Arg shows maximum percentage response of 58.3%. Gly-Gly-Arg act as pheromones and controlls larval release in subtidal crustaceans.
    Gly-Gly-Arg
  • HY-P4290
    Antiulcer Agent 2 111543-77-2 98%
    Antiulcer Agent 2 is a tetrapeptide containing aspartic acid, alanine, histidine, and lysine. Antiulcer Agent 2 is present at the N-terminal of human albumin. Antiulcer Agent 2 has potential applications in ulcers and active oxygen generation.
    Antiulcer Agent 2
  • HY-P4397
    (d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin 115499-13-3 98%
    (d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin, an oxytocin receptor antagonist, abolishes oxytocin-enhanced inhibitory postsynaptic currents in CA1 pyramidal neurons.
    (d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin
  • HY-P4405
    (D-Ala2)-GRF (1-29) amide (human) 89453-59-8 98%
    (D-Ala2)-GRF (1-29) amide (human) is a superagonist of GRF, exhibiting extremely high GH-releasing activity about 50 times that of GRF (1-29) in both pigs and rats.
    (D-Ala2)-GRF (1-29) amide (human)
  • HY-P4413
    (Des-Glu5)-ACTH (1-24) (human, bovine, rat) 1815617-95-8 98%
    (Des-Glu5)-ACTH (1-24) (human, bovine, rat) is an analogue of Adrenocorticotropic hormone (ACTH; HY-106373). ACTH is a polypeptide tropic hormone produced by the anterior pituitary gland, regulating cortisol and androgen production.
    (Des-Glu5)-ACTH (1-24) (human, bovine, rat)
  • HY-P4432
    (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon) 88848-87-7 98%
    (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon) is a GnRH analog that induces ovulation and/or spawning in farmed fish.
    (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon)
  • HY-P4456
    (Des-His6)-ACTH (1-24) (human, bovine, rat) 1926163-11-2 98%
    (Des-His6)-ACTH (1-24) (human, bovine, rat) is an analogue of Adrenocorticotropic hormone (ACTH; HY-106373). ACTH is a polypeptide tropic hormone produced by the anterior pituitary gland, regulating cortisol and androgen production.
    (Des-His6)-ACTH (1-24) (human, bovine, rat)
  • HY-P4523
    FA-Ala-Arg 76079-06-6 98%
    FA-Ala-Arg is a dipeptide with furylacryloyl group. FA-Ala-Arg breaks down to produce arginine. While cell-surface Carboxypeptidase-D (CPD) also increases intracellular Arg, which is converted to nitric oxide (NO). FA-Ala-Arg enhances NO production in MCF-7 cells. FA-Ala-Arg also increases the cell survival of prolactin (PRL)-treated cells, PRL regulates CPD mRNA levels in cells.
    FA-Ala-Arg
  • HY-P4542
    (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) 150646-45-0 98%
    (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) is a CRF antagonist. (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) prevents the IL-1a induced Luteinizing hormone (LH) inhibition.
    (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat)
  • HY-P4564
    (D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH 1926163-38-3 98%
    (D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH). LHRH plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
    (D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH
  • HY-P4568
    (D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH 1926163-39-4 98%
    (D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH). LHRH plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
    (D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH
  • HY-P4577
    (D-Tyr5,D-Ser(tBu)6,Azagly10)-LHRH 1426173-74-1 98%
    (D-Tyr5,D-Ser(tBu)6,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH). LHRH plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
    (D-Tyr5,D-Ser(tBu)6,Azagly10)-LHRH
  • HY-P4657
    Human Growth Hormone (1-43) 96827-07-5 98%
    Human Growth Hormone (1-43) is an N-terminal fragment of human growth hormone with specific and pronounced insulin-like activity. Human Growth Hormone (1-43) can be used to study the function and metabolic pathways of growth hormone, a potential obesity-related factor.
    Human Growth Hormone (1-43)
  • HY-P4675
    LHRH free acid 35263-73-1 99.92%
    LHRH (free acid), the luteinizing hormone-releasing hormone, is a neuropeptide hypothalamic. LHRH regulates reproduction. LHRH can be used for the research of cancer.
    LHRH free acid
  • HY-P4688
    (Ser(Ac)4,D-Ser(tBu)6,Azagly10)-LHRH 1926163-83-8 98%
    (Ser(Ac)4,D-Ser(tBu)6,Azagly10)-LHRH is an important peptide hormone.
    (Ser(Ac)4,D-Ser(tBu)6,Azagly10)-LHRH
  • HY-P4690
    pTH (13-34) (human) 81306-64-1 98%
    pTH (13-34) (human) is apTH ((Human parathyroid hormone) fragment.
    pTH (13-34) (human)
  • HY-P4692
    pTH (1-44) (human) 85568-24-7 98%
    pTH (1-44) (human) is apTH ((Human parathyroid hormone) fragment.
    pTH (1-44) (human)
Cat. No. Product Name / Synonyms Application Reactivity