2. Endocrinology

Endocrinology

Endocrinology

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Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-19580
    Ramixotidine 84071-15-8 98%
    Ramisotidine is a histamine H2 receptor antagonist that can inhibit gastric acid secretion stimulated by pentagastrin.
    Ramixotidine
  • HY-19586
    Albifylline 107767-55-5 98%
    Albifylline (A 81-3138; HWA-138) is a Xanthine (HY-W017389) derivate. Albifylline reduces the shock-induced leukocyte adhesions to the sinusoidal endothelium in the liver after hemorrhagic shock and improves microvascular blood flow in the liver.
    Albifylline
  • HY-19633
    CS-003 Free base 191672-52-3 98%
    CS-003 Free base (CS-003), a triple tachykinin receptor antagonist, shows high affinities for human (Neurokinin) NK1, NK2 and NK3 receptors with Ki values of 2.3 nM, 0.54 nM and 0.74 nM, respectively. CS-003 Free base (CS-003) has therapeutic efficacy on respiratory diseases associated with neurokinins.
    CS-003 Free base
  • HY-19942
    TD-5471 530084-87-8 98%
    TD-5471 is a potent and selective full agonist of the human β2-adrenoceptor.
    TD-5471
  • HY-24574
    (E)-5-Octadecene 7206-21-5 98%
    (E)-5-Octadecene ((E)-Octadec-5-ene) is a sex pheromone or a related chemical component. (E)-5-Octadecene has effect on destruction of sexual attraction of female moth of rice borers moth (Chilo suppressalis Walker).
    (E)-5-Octadecene
  • HY-30234
    Clemizole 442-52-4 98%
    Clemizole is an H1 histamine receptor antagonist, is found to substantially inhibit HCV replication. Clemizole is an inhibitor of TRPC5 channel. The IC50 of Clemizole for RNA binding by NS4B is 24±1 nM, whereas its EC50 for viral replication is 8 µM.
    Clemizole
  • HY-A0142
    Dapiprazole 72822-12-9 98%
    Dapiprazole is a potent, selective and orally active alpha-1 adrenoceptor antagonist. Dapiprazole suppresses the opioid withdrawal symptoms. Dapiprazole is also used as eye drops for reversing mydriasis.
    Dapiprazole
  • HY-A0267
    Bitolterol 30392-40-6 98%
    Bitolterol is a β2-adrenergic agonist with bronchodilator activity. Bitolterol is classified as a prodrug and is primarily used for the suppression of respiratory diseases. Bitolterol is considered safe for use during breastfeeding, as the amount that can enter breast milk is very limited.
    Bitolterol
  • HY-A0287
    Clomiphene 911-45-5 98%
    Clomiphene (Clomifene) is an orally active compound used for infertility. Clomiphene (Clomifene) is a simple, relatively safe, easily administered and well-tolerated efficacious compound to induce ovulation.
    Clomiphene
  • HY-B0431
    Phenoxybenzamine 59-96-1 98%
    Phenoxybenzamine is a nonselective, irreversible, orally active α-adrenoceptor antagonist that is commonly used for the research of hypertension, specifically caused by pheochromocytoma. Phenoxybenzamine also shows antitumor activity.
    Phenoxybenzamine
  • HY-B1001
    Todralazine 14679-73-3 98%
    Todralazine (Ecarazine) is an anti-hypertensive agent, acts as a β2AR blocker, with antioxidant and free radical scavenging activity.
    Todralazine
  • HY-B1034
    Vanitiolide 17692-71-6 98%
    Vanitiolide is a cholagogue.
    Vanitiolide
  • HY-B1711
    Norfenefrine 536-21-0
    Norfenefrine is an orally active, endogenously found α-adrenergic agonist and can be used for the research of female stress incontinence.
    Norfenefrine
  • HY-B1951
    Trietazine 1912-26-1 98%
    Trietazine is a selective pre- and post-emergence glyphosate-based herbicide. Trietazine residues cause human health risks, such as cancer, birth defects, and hormone imbalance.
    Trietazine
  • HY-N2924
    β-Amyrin palmitate 5973-06-8 98%
    β-Amyrin palmitate shows HMG-CoA reductase inhibition. And β-Amyrin palmitate has anti-diabetes mellitus activity.
    β-Amyrin palmitate
  • HY-N3101
    Pedalitin 22384-63-0 98%
    Pedalitin is a inhibitor of tyrosinase（IC50=0.28 mM） and α-glucosidase（IC50=0.29 mM）.
    Pedalitin
  • HY-N3257
    Millewanin G 874303-33-0 98%
    Millewanin G is a prenylated isoflavonoid with antiestrogenic activity (IC50=29 μM). Millewanin G can be isolated from the leaves of M. pachycarpa cultivated in Japan.
    Millewanin G
  • HY-N3503
    Ganoderlactone D 1801934-15-5 ≥99.0%
    Ganoderlactone D shows inhibitory effects of yeast α-Glucosidase with IC50 values of 41.7 μM.
    Ganoderlactone D
  • HY-N5103
    Genistein 7,4'-di-O-β-D-glucoside 36190-98-4 98%
    Genistein 7,4'-di-O-β-D-glucoside is a natural product with significantly estrogenic proliferative effect in MCF-7 cells.
    Genistein 7,4'-di-O-β-D-glucoside
  • HY-N6181
    Terrelumamide A 1802497-05-7 98%
    Terrelumamide A is a lumazine-containing peptide. Terrelumamide A is isolated from the culture broth of the marine-derived fungus Aspergillus terreus. Terrelumamide A exhibits pharmacological activity by improving insulin sensitivity. Terrelumamide A has the potential in the application of DNA sequence recognition.
    Terrelumamide A
Cat. No. Product Name / Synonyms Application Reactivity