2. Endocrinology

Endocrinology

Endocrinology

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Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-13213
    AM211 1175526-27-8 98.79%
    AM211 is a potent, selective and orally bioavailable prostaglandin D2 (PGD2) receptor type 2 (DP2) antagonist, with IC50s of 4.9 nM, 7.8 nM, 4.9 nM, 10.4 nM for human, mouse, guinea pig, and rat DP2, respectively.
    AM211
  • HY-13796
    IPSU 1373765-19-5 98.0%
    IPSU is a selective, orally available and brain penetrant OX2R antagonist with a pKi of 7.85.
    IPSU
  • HY-14298
    Milveterol hydrochloride 804518-03-4 98.20%
    Milveterol hydrochloride is a long-acting β2-adrenergic receptor agonist. Milveterol hydrochloride can be used in study asthma and chronic obstructive pulmonary disease (COPD) .
    Milveterol hydrochloride
  • HY-15015
    OT-R antagonist 1 364071-17-0 ≥98.0%
    OT-R antagonist 1 is a new potent and selective nonpeptide low molecular weight OT-R antagonist.
    OT-R antagonist 1
  • HY-15104
    Ronacaleret hydrochloride 702686-96-2 99.81%
    Ronacaleret hydrochloride (SB 751689A) is an orally active, potent, and selective calcium-sensing receptor (CaSR) antagonist that stimulates endogenous parathyroid hormone release from the parathyroid glands. Ronacaleret hydrochloride (SB 751689A) is used for the study of postmenopausal osteoporosis.
    Ronacaleret hydrochloride
  • HY-15541
    Zaltidine 85604-00-8 99.49%
    Zaltidine dihydrochloride (CP-5736 dihydrochloride) is a highly specific H2 receptor antagonist with antisecretion activity. Zaltidine dihydrochloride reduces the stimulant effect of histamine on gastric acid secretion by binding to histamine H2 receptors on gastric parietal cells, thus reducing gastric acid production. Zaltidine dihydrochloride can be used in the study of gastric acid-related diseases such as duodenal ulcers.
    Zaltidine
  • HY-16316
    Metipranolol hydrochloride 36592-77-5 99.92%
    Metipranolol hydrochloride is a non-selective β adrenergic receptor blocking agent.
    Metipranolol hydrochloride
  • HY-16344
    Nedocromil sodium 69049-74-7 98%
    Nedocromil sodium suppresses the action or formation of multiple mediators, including histamine, leukotriene C4 (LTC4), and prostaglandin D2 (PGD2).
    Nedocromil sodium
  • HY-17450
    Aplaviroc 461443-59-4 98%
    Aplaviroc (AK 602), a SDP derivative, is a CCR5 antagonist, with IC50s of 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL and HIV-1MOKW.
    Aplaviroc
  • HY-19529
    Ro 46-2005 150725-87-4 98.32%
    Ro 46-2005 is a novel synthetic non-peptide endothelin receptor antagonist, inhibits the specific binding of 125I-ET-1 to human vascular smooth muscle cells (ETA receptor) with IC50 of 220 nM.
    Ro 46-2005
  • HY-76937
    Impurity of Doxercalciferol 127516-23-8
    Impurity of Doxercalciferol is an impurity of doxercalciferol, which is a synthetic analog of ergocalciferol (vitamin D2), used as a agent for secondary hyperparathyroidism and metabolic bone disease, and it suppresses parathyroid synthesis and secretion.
    Impurity of Doxercalciferol
  • HY-B0487
    Ethisterone 434-03-7 98.02%
    Ethisterone (Pregneninolone), a synthetic steroidal estrogen, is an orally active steroidal contraceptive agent. Ethisterone is reported for androgenic activity, used for the research of the gynecological disorders.
    Ethisterone
  • HY-B1341
    Norethynodrel 68-23-5
    Norethynodrel (Enidre) is a 19-nortestosterone derivative to be used as a progestagen. Norethynodrel can be used for researching inhibition of ovulation. Norethynodrel is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Norethynodrel
  • HY-N2448
    Lindleyin 59282-56-3 99.95%
    Lindleyin, isolated from Rhei rhizoma, mediates hormonal effects through estrogen receptors. Lindleyin binds to ERα with estrogenic activity.
    Lindleyin
  • HY-N2924
    β-Amyrin palmitate 5973-06-8 ≥98.0%
    β-Amyrin palmitate shows HMG-CoA reductase inhibition. And β-Amyrin palmitate has anti-diabetes mellitus activity.
    β-Amyrin palmitate
  • HY-N3078
    p-Hydroxyphenethyl trans-ferulate 84873-15-4 99.68%
    p-Hydroxyphenethyl trans-ferulate has anti-hyperglycemic (yeast α-glucosidase, IC50=19.24 ± 1.73 µM), antioxidant, and anti-inflammatory activities. p-Hydroxyphenethyl trans-ferulate shows inhibiting anticancer and serotonergic activity.
    p-Hydroxyphenethyl trans-ferulate
  • HY-N4088
    Pseudolaric acid A-O-β-D-glucopyranoside 98891-44-2 99.67%
    Pseudolaric acid A-O-β-D-glucopyranoside, isolated from Cortex Pseudolaricis, demonstrates antifungal and antifertility activities.
    Pseudolaric acid A-O-β-D-glucopyranoside
  • HY-N4188
    N-Benzyloctadecanamide 5327-45-7 99.72%
    N-Benzyloctadecanamide (N-Benzylstearamide) is a macamide, a distinct class of secondary metabolites in Lepidium meyenii Walp. (Maca).
    N-Benzyloctadecanamide
  • HY-N4200
    S-Dihydrodaidzein 879559-75-8 98%
    S-Dihydrodaidzein is the (S)-enantiomer of dihydrodaidzein which is one of the most prominent dietary phytoestrogens.
    S-Dihydrodaidzein
  • HY-N7267
    31-Norlanostenol 16910-39-7 99.94%
    31-Norlanostenol is a triterpenic compound isolated from the latex of Euphorbia officinarum. 31-Norlanostenol can act as efficient insect growth regulator on S. frugiperda and Tenebrio molitor.
    31-Norlanostenol
Cat. No. Product Name / Synonyms Application Reactivity