2. Endocrinology

Endocrinology

Endocrinology

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Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B0326
    Alibendol 26750-81-2 99.94%
    Alibendol can be taken orally. It has anti-spasmodic properties and promotes bile secretion, making it useful for research on digestive system issues like indigestion, nausea, vomiting, and constipation.
    Alibendol
  • HY-B0459
    Scopine 498-45-3 ≥98.0%
    Scopine is the metabolite of anisodine, which is a α1-adrenergic receptor agonist and used in the treatment of acute circulatory shock.
    Scopine
  • HY-B0652
    Etonogestrel 54048-10-1 99.14%
    Etonogestrel (3-Oxodesogestrel), a biologically active metabolite of progestin Desogestrel, binds with high affinity to progesterone receptors and estrogen receptors in the target organs. Etonogestrel induce FKBP51 mRNA and protein expression in cultured human endometrial stromal cells (HESCs).
    Etonogestrel
  • HY-B1089
    Ethynodiol diacetate 297-76-7 99.85%
    Ethynodiol diacetate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Ethynodiol diacetate
  • HY-B1111
    Amitraz 33089-61-1
    Amitraz is a non-systemic acaricide and insecticide with alpha-adrenergic agonist activity that interacts with octopamine receptors in the central nervous system and inhibits monoamine oxidase and prostaglandin synthesis.
    Amitraz
  • HY-P4060
    Pancreatic polypeptide 59763-91-6 98.81%
    Pancreatic polypeptide is a peptide secreted by the endocrine PP cells of the pancreas that regulates pancreatic secretory activity and also affects hepatic glycogen stores and gastrointestinal secretion.
    Pancreatic polypeptide
  • HY-133677
    Mono(2-ethyl-5-hydroxyhexyl) phthalate 40321-99-1 99.03%
    Mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) is an oxidative metabolite of Di(2-ethylhexyl) phthalate (DEHP). Mono(2-ethyl-5-hydroxyhexyl) phthalate may protective sperm DNA damage. Di(2-ethylhexyl) phthalate is the predominant plasticizer added to rigid polyvinyl chloride (PVC) to impart flexibility, temperature tolerance, optical clarity, strength and resistance to kinking.
    Mono(2-ethyl-5-hydroxyhexyl) phthalate
  • HY-B1694A
    Methoxyphenamine hydrochloride 5588-10-3 ≥98.0%
    Methoxyphenamine hydrochloride, a non-regulated analog of Methamphetamine, is a β-adrenergic receptor agonist used as a bronchodilator.
    Methoxyphenamine hydrochloride
  • HY-U00205
    Dopexamine hydrochloride 86484-91-5 99.71%
    Dopexamine hydrochloride is a β2 adrenergic receptor agonist.
    Dopexamine hydrochloride
  • HY-135794S
    11-Ketodihydrotestosterone-d3 2479914-02-6 99.00%
    11-Ketodihydrotestosterone-d3 is the deuterium labeled 11-Ketodihydrotestosterone. 11-Ketodihydrotestosterone (11-KDHT; 5α-Dihydro-11-keto testosterone) is an endogenous steroid and a metabolite of 11β-Hydroxyandrostenedione. 11-Ketodihydrotestosterone is an active androgen and is also a potent androgen receptor (AR) agonist with a Ki of 20.4 nM and an EC50 of 1.35 nM for human AR. 11-Ketodihydrotestosterone drives gene regulation, protein expression and cell growth in androgen-dependent prostate cancer cells.
    11-Ketodihydrotestosterone-d3
  • HY-RS29442
    Nsun2 Mouse Pre-designed siRNA Set A
    Nsun2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nsun2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Components
    Nsun2 Mouse Pre-designed siRNA Set A-1
    Nsun2 Mouse Pre-designed siRNA Set A-2
    Nsun2 Mouse Pre-designed siRNA Set A-3
    siRNA Negative Control
    FAM-labeled siRNA Negative Control
    GAPDH Positive Control siRNA (Mouse)
    Nsun2 Mouse Pre-designed siRNA Set A
  • HY-W007273
    11-Dodecyn-1-ol 18202-10-3
    11-Dodecyn-1-ol is a synthetic intermediate of the sex pheromone (Z,E)-11,13,15-Hexadecatrienyl acetate for Thaumetopoea processionea.
    11-Dodecyn-1-ol
  • HY-W040047
    Pregnanediol 3-glucuronide 1852-49-9 ≥98.0%
    Pregnanediol 3-glucuronide is the major terminal metabolite of progesterone, playing an important role in physiological processes, such as the female menstrual cycle, pregnancy (supports gestation), embryogenesis and maternal immune response of humans and other species.
    Pregnanediol 3-glucuronide
  • HY-W116007
    Octamethylcyclotetrasiloxane 556-67-2 99.85%
    Octamethylcyclotetrasiloxane promotes the anchorage-independent growth of MCF-10A and MCF-10F cells. Octamethylcyclotetrasiloxane induces DNA damage, inhibits the expression of DNA-repairing protein BRCA1 under long-term and high-concentration exposure. Octamethylcyclotetrasiloxane exhibits intrinsic estrogenic activity.
    Octamethylcyclotetrasiloxane
  • HY-W561401
    Blattellaquinone 849762-24-9
    Blattellaquinone is a sex pheromone isolated from German cockroaches.
    Blattellaquinone
  • HY-14401
    Encaleret 787583-71-5 99.88%
    Encaleret (CLTX-305) is an orally active antagonist of the calcium-sensing receptor (CaSR), with an IC50 of 0.012 μM. Encaleret can promote the secretion of parathyroid hormone. Encaleret can be used in the research of diseases such as osteoporosis and autosomal dominant hypocalcemia type 1.
    Encaleret
  • HY-104003
    S 38093 862896-30-8 99.86%
    S 38093 is a brain-penetrant, orally active antagonist of H3 receptor, with Kis of 8.8, 1.44 and 1.2 μM for rat, mouse and human H3 receptors, respectively.
    S 38093
  • HY-128351
    SHR1653 2231770-73-1 99.69%
    SHR1653 is a highly potent, selective and brain penetrated oxytocin receptor (OTR) antagonist, with an IC50 of 15 nM for hOTR.
    SHR1653
  • HY-12956S
    Dinoprost-d4 34210-11-2 ≥99.0%
    Dinoprost-d4 is the deuterium labeled Dinoprost. Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost plays a key role in the onset and progression of labour.
    Dinoprost-d4
  • HY-148804
    Vemtoberant 2169905-68-2 99.08%
    Vemtoberant is an β3 Adrenergic Receptor antagonist. Vemtoberant can be used for research of β3 adrenergic receptor-mediated disorder, such as, heart failure.
    Vemtoberant
Cat. No. Product Name / Synonyms Application Reactivity