2. Endocrinology

Endocrinology

Endocrinology

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Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P5214
    Vasopressin Dimer (anti-parallel) (TFA) 98%
    Vasopressin Dimer (anti-parallel) TFA is an anti-parallel dimer of Vasopressin (HY-B1811). Vasopressin Dimer (anti-parallel) TFA can activate four G protein-coupled receptors, V1aR, V1bR, V2R, and OTR.
    Vasopressin Dimer (anti-parallel) (TFA)
  • HY-P5518
    [Des-Arg10]-HOE I40 1054763-33-5 98%
    [Des-Arg10]-HOE I40 is a potent bradykinin B1 receptor antagonist.
    [Des-Arg10]-HOE I40
  • HY-P5523
    iE-DAP 592520-07-5 98%
    iE-DAP is a Nod1 agonist. Nod1 recognition of iE-DAP can activate the NF-κB pathway, leading to an inflammatory cytokine response. iE-DAP can be used for the research of maternal-fetal inflammation and preterm labor.
    iE-DAP
  • HY-P5866
    Allatotropin 120928-88-3 98%
    Allatotropin (Manse-AT) is a 13 amino acid neuropeptide. Allatotropin activates inositol 1,4,5-trisphosphate (IP3) pathway, and the biosynthesis of juvenile hormone (JH) in Manduca sexta.
    Allatotropin
  • HY-P6176
    JLB2-110c 3032608-72-0 98%
    JLB2-110c activates MCRs receptor (mMC4R EC50 = 0.34 nM) and has a strong in vivo appetite suppressant effect.
    JLB2-110c
  • HY-100141
    Ancarolol 75748-50-4 98%
    Ancarolol is a beta-adrenergic blocking agent.
    Ancarolol
  • HY-100150
    Mepixanox 17854-59-0 98%
    Mepixanox (Pimexone) is an analeptic agent used in respiratory and cardiorespiratory insufficiency.
    Mepixanox
  • HY-10017A
    (R)-SCH 546738 2181148-54-7 99.75%
    (R)-SCH 546738 is the R-isomer of SCH 546738 (HY-10017). SCH 546738 is an orally active and non-competitive antagonist for CXCR3 with Ki of 0.4 nM for human CXCR3 receptor.
    (R)-SCH 546738
  • HY-100191
    BMY-25271 78441-82-4 98%
    BMY-25271 is a histamine H2 receptor antagonist.
    BMY-25271
  • HY-100255
    Tiodazosin 66969-81-1 98%
    Tiodazosin is a potent competitive postsynaptic alpha adrenergic receptor antagonist.
    Tiodazosin
  • HY-100261
    CCR5 antagonist 1 716354-86-8 98%
    CCR5 antagonist 1 is a CCR5 antagonist which can inhibit HIV replication extracted from WO 2004054974 A2.
    CCR5 antagonist 1
  • HY-100280
    Pirolate 55149-05-8 98%
    Pirolate is a histamine H1 receptor antagonist.
    Pirolate
  • HY-100287
    2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide 137089-36-2 98%
    2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide is a compound that inhibits stress-induced ulcer and low toxicity, and can maintain the content of phospholipase A2 and prostaglandin E2 in ulcerated rats induced by water immersed restrained stress.
    2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide
  • HY-100297
    MK-447 58456-91-0 98%
    MK-447 is a free radical scavenger, also a nonsteroidal antiinflammatory agent, and enhances the formation of the endoperoxide, PGH2, and other prostaglandins.
    MK-447
  • HY-100301
    FR167344 free base 215258-13-2 98%
    FR167344 free base is an orally active, nonpeptide bradykinin receptor B2 antagonist. FR167344 free base shows a high affinity binding to the B2 receptor with an IC50 value of 65 nM and no binding affinity for the B1 receptor.
    FR167344 free base
  • HY-100305
    Substituted piperidines-1 170842-46-3 98%
    Substituted piperidines-1 is a compound that can promote the release of growth hormone in humans and animals.
    Substituted piperidines-1
  • HY-100318
    NGD-4715 476322-70-0 98%
    NGD-4715 is a selective and orally active melanin-concentrating hormone receptor 1 (MCHR1) antagonist .
    NGD-4715
  • HY-10052R
    Aprepitant (Standard) 170729-80-3
    Aprepitant (Standard) is the analytical standard of Aprepitant. This product is intended for research and analytical applications. Aprepitant (MK-0869) is a selective and high-affinity neurokinin 1 receptor antagonist with a Kd of 86 pM.
    Aprepitant (Standard)
  • HY-10053S
    Maropitant-d3 2124295-52-7 98%
    Maropitant-d3 is the deuterium labeled Maropitant. Maropitant is a selective and orally active neurokinin (NK1) receptor antagonist. Maropitant acts by blocking the binding of substance P within the emetic center and the chemoreceptor trigger zone (CRTZ). Maropitant is highly effective in preventing vomiting.
    Maropitant-d3
  • HY-100571
    Cloprostenol isopropyl ester 157283-66-4 98%
    Cloprostenol isopropyl ester, a prostaglandin F2α analogs, is the intermediate of (+)-Cloprostenol (HY-107381). Cloprostenol isopropyl ester is a FP receptor agonist with a Ki value of 28 nM.
    Cloprostenol isopropyl ester
Cat. No. Product Name / Synonyms Application Reactivity