2. Endocrinology

Endocrinology

Endocrinology

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Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P4413
    (Des-Glu5)-ACTH (1-24) (human, bovine, rat) 1815617-95-8 98%
    (Des-Glu5)-ACTH (1-24) (human, bovine, rat) is an analogue of Adrenocorticotropic hormone (ACTH; HY-106373). ACTH is a polypeptide tropic hormone produced by the anterior pituitary gland, regulating cortisol and androgen production.
    (Des-Glu5)-ACTH (1-24) (human, bovine, rat)
  • HY-P4432
    (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon) 88848-87-7 98%
    (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon) is a GnRH analog that induces ovulation and/or spawning in farmed fish.
    (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon)
  • HY-P4456
    (Des-His6)-ACTH (1-24) (human, bovine, rat) 1926163-11-2 98%
    (Des-His6)-ACTH (1-24) (human, bovine, rat) is an analogue of Adrenocorticotropic hormone (ACTH; HY-106373). ACTH is a polypeptide tropic hormone produced by the anterior pituitary gland, regulating cortisol and androgen production.
    (Des-His6)-ACTH (1-24) (human, bovine, rat)
  • HY-P4523
    FA-Ala-Arg 76079-06-6 98%
    FA-Ala-Arg is a dipeptide with furylacryloyl group. FA-Ala-Arg breaks down to produce arginine. While cell-surface Carboxypeptidase-D (CPD) also increases intracellular Arg, which is converted to nitric oxide (NO). FA-Ala-Arg enhances NO production in MCF-7 cells. FA-Ala-Arg also increases the cell survival of prolactin (PRL)-treated cells, PRL regulates CPD mRNA levels in cells.
    FA-Ala-Arg
  • HY-P4542
    (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) 150646-45-0 98%
    (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) is a CRF antagonist. (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) prevents the IL-1a induced Luteinizing hormone (LH) inhibition.
    (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat)
  • HY-P4564
    (D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH 1926163-38-3 98%
    (D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH). LHRH plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
    (D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH
  • HY-P4568
    (D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH 1926163-39-4 98%
    (D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH). LHRH plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
    (D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH
  • HY-P4577
    (D-Tyr5,D-Ser(tBu)6,Azagly10)-LHRH 1426173-74-1 98%
    (D-Tyr5,D-Ser(tBu)6,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH). LHRH plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
    (D-Tyr5,D-Ser(tBu)6,Azagly10)-LHRH
  • HY-P4657
    Human Growth Hormone (1-43) 96827-07-5 98%
    Human Growth Hormone (1-43) is an N-terminal fragment of human growth hormone with specific and pronounced insulin-like activity. Human Growth Hormone (1-43) can be used to study the function and metabolic pathways of growth hormone, a potential obesity-related factor.
    Human Growth Hormone (1-43)
  • HY-P4688
    (Ser(Ac)4,D-Ser(tBu)6,Azagly10)-LHRH 1926163-83-8 98%
    (Ser(Ac)4,D-Ser(tBu)6,Azagly10)-LHRH is an important peptide hormone.
    (Ser(Ac)4,D-Ser(tBu)6,Azagly10)-LHRH
  • HY-P4690
    pTH (13-34) (human) 81306-64-1 98%
    pTH (13-34) (human) is apTH ((Human parathyroid hormone) fragment.
    pTH (13-34) (human)
  • HY-P4692
    pTH (1-44) (human) 85568-24-7 98%
    pTH (1-44) (human) is apTH ((Human parathyroid hormone) fragment.
    pTH (1-44) (human)
  • HY-P4693
    (Ser(tBu)6,Azagly10)-LHRH 184686-52-0 98%
    (Ser(tBu)6,Azagly10)-LHRH is a potent aza-GLY analog.
    (Ser(tBu)6,Azagly10)-LHRH
  • HY-P4696
    pTH (3-34) (bovine) 51257-86-4 98%
    pTH (3-34) (bovine) is apTH ((Human parathyroid hormone) fragment.
    pTH (3-34) (bovine)
  • HY-P4700
    pTH (53-84) (human) 89439-30-5 98%
    pTH (53-84) (human) is apTH ((Human parathyroid hormone) fragment.
    pTH (53-84) (human)
  • HY-P4852
    ACTH (2-24) (human, bovine, rat) 67654-32-4 98%
    ACTH (2-24) (human, bovine, rat) is a peptide analogue of ACTH.
    ACTH (2-24) (human, bovine, rat)
  • HY-P4856
    pTH-Related Protein (1-40) (human, mouse, rat) 120298-73-9 98%
    pTH-Related Protein (1-40) (human, mouse, rat) stimulates calcium uptake in rat intestinal cells through PTHR1 receptor and PKCα/β signaling pathways. pTH-Related Protein (1-40) up-regulates parathyroid hormone 1 receptor (PTHR1) protein, four transcellular calcium transporters, potential vanillin member 6 (TRPV6), calcium-binding protein-D9K (CaBP-D9k), sodium-calcium Exchanger 1 (NCX1) and plasma membrane calcium ATPase 1 (PMCA1).
    pTH-Related Protein (1-40) (human, mouse, rat)
  • HY-P4857
    pTH-Related Protein (7-34) amide (human, mouse, rat) 115695-30-2 98%
    pTH-Related Protein (7-34) amide (human, mouse, rat) is a potent antagonist of parathyroid hormone (PTH).
    pTH-Related Protein (7-34) amide (human, mouse, rat)
  • HY-P4990
    Pro8-Oxytocin 24327-19-3 98%
    Pro8-Oxytocin is a a modified oxytocin (OXT) ligand. Pro8-Oxytocin produces more potent and efficacious responses at primate OXTR and stronger behavioral effects than the consensus mammalian OXT ligand (Leu8-Oxytocin). Pro8-Oxytocin produce a less efficacious response than Vasopressin (HY-B1811) (AVP) at human AVPR1a and higher efficacious response than AVP at marmoset AVPR1a.
    Pro8-Oxytocin
  • HY-P5017
    (Val3,Pro8)-Oxytocin 2134138-89-7 98%
    (Val3,Pro8)-Oxytocin is the Gq-dependent pathway agonist. (Val3,Pro8)-Oxytocin is also a weaker agonist for the β-arrestin engagement and endocytosis toward the oxytocin receptor (OXTR).
    (Val3,Pro8)-Oxytocin
Cat. No. Product Name / Synonyms Application Reactivity