2. Cardiovascular Disease

Cardiovascular Disease

Cardiovascular Disease

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Cardiovascular diseases (CVDs) are the leading causes of death and disability worldwide. CVDs include diseases of the heart, vascular diseases of the brain and diseases of blood vessels. Caused by atherosclerosis, coronary heart disease and cerebrovascular disease are the most common forms of CVDs. Other less common forms of CVDs include rheumatic heart disease and congenital heart disease. A large percentage of CVDs is preventable through the reduction of behavioral risk factors such as tobacco use, physical inactivity and unhealthy diet. Dietary sodium reduction can alleviate the long-term risk of cardiovascular disease events. Statin therapy is an effective intervention in both the primary and secondary preventions of CVDs in those who are at high risk.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N5057
    Przewalskinic acid A 136112-75-9 98.64%
    Przewalskinic acid A is a phenolic acid found in the Salvia przewalskii Maxim herb. Phenolic acids show potent antioxidant activities and potential effects in protecting against brain and heart damage caused by ischemia reperfusion.
    Przewalskinic acid A
  • HY-N6243
    Veratrosine 475-00-3 ≥99.0%
    Veratramine is a steroidal alkaloid extracted from the roots and rhizomes of Veratrum californicum.
    Veratrosine
  • HY-N6249
    Feretoside 27530-67-2 98.69%
    Feretoside, a phenolic compound extracted from the barks of E. ulmoides, is a HSP inducer which act as cytoprotective agent.
    Feretoside
  • HY-N6574
    Marinobufogenin 470-42-8 ≥99.0%
    Marinobufogenin is a strong inhibitor of Na+/K+ ATPase that has been identified in mammalian plasma.
    Marinobufogenin
  • HY-N6581
    Notoginsenoside T5 769932-34-5
    Notoginsenoside T5 is a dammarane 61 glycoside. Notoginsenoside T5 is isolated from the acidic deglycosylation of saponins from the roots of P. 62 notoginseng.
    Notoginsenoside T5
  • HY-N6617
    Norswertianolin 54954-12-0 99.27%
    Norswertianolin acts as a CSE activator and is isolated from G. acuta. Norswertianolin may be a potential agent for cardiovascular diseases.
    Norswertianolin
  • HY-N7671
    Euphorbetin 35897-99-5
    Euphorbetin exhibits anticoagulant activities.
    Euphorbetin
  • HY-N8144
    Niga-ichigoside F1 95262-48-9 ≥99.0%
    Niga-ichigoside F1, an orally active ursane triterpenoid, has antihyperlipidemic and antioxidant activities. Niga-ichigoside F1 can prevent high-fat diet (HFD)-induced hepatic steatosis.
    Niga-ichigoside F1
  • HY-N9351
    Cleistanthin B 30021-77-3 ≥99.0%
    Cleistanthin B (Diphyllin O-glucoside) is an orally active arylnaphthalene lignan lactone glycoside. Cleistanthin B exhibits anti-SARS-CoV-2 effects in Vero cells, with EC50 of 6.51 µM. Cleistanthin B also exhibits antitumor, diuretic and antihypertensive effects in vivo.
    Cleistanthin B
  • HY-N9372
    Crocetin β-D-glucopyranoside 58050-17-2 98.59%
    Crocetin β-D-glucopyranoside is an active part of saffron pigments extracted from patent CN 105935363 A.
    Crocetin β-D-glucopyranoside
  • HY-P0204
    Endothelin-3, human, mouse, rabbit, rat 117399-93-6 98%
    Endothelin-3, human, mouse, rabbit, rat is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.
    Endothelin-3, human, mouse, rabbit, rat
  • HY-P0207
    Endothelin-2 (49-69), human 123562-20-9 98%
    Endothelin-2 (49-69), human (Endothelin-2 (human, canine)) is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.
    Endothelin-2 (49-69), human
  • HY-P0226
    TFLLR-NH2 197794-83-5 99.04%
    TFLLR-NH2 is a selective PAR1 agonist with an EC50 of 1.9 μM.
    TFLLR-NH2
  • HY-P0258
    Mas7 145854-59-7
    Mas7 (Mastoparan 7), a structural analogue of mastoparan, is an activator of heterotrimeric Gi proteins and its downstream effectors.
    Mas7
  • HY-P0318
    Hemorphin-7 152685-85-3 98%
    Hemorphin-7 is a hemorphin peptide, an endogenous opioid peptide derived from the β-chain of hemoglobin. Hemorphin peptides exhibits antinociceptive and antihypertensive activities, activating opioid receptors and inhibiting angiotensin-converting enzyme (ACE).
    Hemorphin-7
  • HY-P1025
    M40 143896-17-7 98%
    M40 is an antagonist or a weak agonist for galanin receptor depending on different subtypes of galanin receptors in the brain, hypothalamus, hippocampus, amygdala and pancreas.
    M40
  • HY-P1112
    Sarafotoxin S6a 126738-34-9 98.45%
    Sarafotoxin S6a, a sarafotoxin analogue, is a endothelin receptor agonist and has an ETA/ETB selectivity profile similar to that of Endothelin-3 (HY-P0204). Sarafotoxin S6a elicits the pig coronary artery with an EC50 value of 7.5 nM.
    Sarafotoxin S6a
  • HY-P1235
    Carperitide 89213-87-6 98%
    Carperitide (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine) is a 28-amino acid hormone, that is normally produced and secreted by the human heart in response to cardiac injury and mechanical stretch. Carperitide (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine) inhibits endothelin-1 secretion in a dose-dependent way.
    Carperitide
  • HY-P1495
    Small Cardioactive Peptide B (SCPB) 84746-43-0 99.69%
    Small Cardioactive Peptide B (SCPB), a neurally active peptide, stimulates adenylate cyclase activity in particulate fractions of both heart and gill tissues with EC50s of 0.1 and 1.0 μM, respectively.
    Small Cardioactive Peptide B (SCPB)
  • HY-P1516
    Angiogenin (108-122) 112173-49-6 98%
    Angiogenin (108-122) is an angiogenin peptide.
    Angiogenin (108-122)
Cat. No. Product Name / Synonyms Application Reactivity