1. Inflammation/Immunology

Inflammation/Immunology

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P10635
    TKD (450-463) 403668-80-4
    TKD (450-463) is a 14-mer peptide (TKDNNLLGRFELSG). TKD (450-463) is able to stimulate the cytolytic and proliferative activity of NK cells at concentrations equivalent to full-length Hsp70 protein.
    TKD (450-463)
  • HY-P10660
    CMV pp65 (415-429) 207847-44-7
    CMV pp65 (415-429) is a CEF control peptide that is derived from the Cytomegalovirus (CMV).
    CMV pp65 (415-429)
  • HY-P10662
    HLA-B*0801-binding EBV peptide 139143-28-5
    HLA-B*0801-binding EBV peptide is an Epstein-Barr virus (EBV) epitope FLRGRAYGL. HLA-B*0801-binding EBV peptide can bind to the HLA-B*0801 molecule. HLA-B*0801-binding EBV peptide can be presented to CD8+ T cells through HLA-B*0801 to activate a specific immune response.
    HLA-B*0801-binding EBV peptide
  • HY-P10663
    EBV EBNA3A (379-387) 160790-25-0
    EBV EBNA3A (379-387) is an antigenic epitope that may elicit the latent-specific CD8+ T cell response in HLA-B*07:02+ individuals.
    EBV EBNA3A (379-387)
  • HY-P10664
    EBV EBNA3B (416-424) 147138-29-2
    EBV EBNA3B (416-424) is an HLA-A11-restricted peptide antigen derived from EBV EBNA3B protein.
    EBV EBNA3B (416-424)
  • HY-P10692
    HB-107 135154-02-8
    HB-107 is a peptide with wound healing properties. HB-107 promotes the proliferation of keratinocytes and increased leukocyte infiltration at the wound site, and it also stimulates cultured endothelial cells to secrete interleukin 8 (IL-8). HB-107 holds potential for research in the fields of wound healing and inflammation.
    HB-107
  • HY-P10693
    CZEN-002 942626-41-7
    CZEN-002 is a derivative of alpha-melanocyte-stimulating hormone that has anti-inflammatory and antibacterial properties, inhibiting the production of TNF-α.
    CZEN-002
  • HY-P10694
    IDR-HH2 1214699-22-5
    IDR-HH2 is an immunomodulatory peptide with the ability to modulate the host cytokine/chemokine environment. IDR-HH2 can promote the adhesion of monocytes and THP-1 cells to fibronectin. Additionally, IDR-HH2 possesses antibacterial activity, inhibiting the activity of both P. aeruginosa and S. aureus with MIC values of 75 µg/mL and 38 µg/mL, respectively.
    IDR-HH2
  • HY-P10701
    Q11 peptide 581799-39-5
    Q11 peptide is a β-sheet-forming peptide that plays an important role in self-assembly and targeted applications. As a scaffold peptide, Q11 peptide can display immunogenic epitopes and is widely used in peptide-based immune vaccine research. Additionally, Q11 peptide can be conjugated with MUC1 glycopeptides for the study of self-assembling, adjuvant-free MUC1 glycopeptide vaccines. Q11 peptide holds great potential for research in the field of cancer immunology.
    Q11 peptide
  • HY-P10707
    Tpp-CAQK
    Tpp-CAQK can bind to mitochondria, enabling the construction of an engineered mitochondrial compound, Mito-Tpp-CAQK, with excellent bioactivity. Mito-Tpp-CAQK can be internalized by macrophages, thereby enhancing the phagocytosis of myelin debris, alleviating mitochondrial dysfunction, and reducing proinflammatory profiles, ultimately facilitating tissue repair and functional recovery in mice after spinal cord injury.
    Tpp-CAQK
  • HY-P10710
    BMP-4 1629625-47-3
    BMP-4 is a penetrating heparin-binding peptide with anti-inflammatory and anti-chondrogenic functions. In murine chondrocytes and macrophages, BMP-4 regulates the iNOS-IFN-IL6 signaling pathway to inhibit the expression of inflammatory proteins such as iNOS, COX2, IFN, and IL6 in a dose-dependent manner, effectively suppressing inflammation and alleviating various arthritis symptoms.
    BMP-4
  • HY-P10715
    Fmoc-KCRGDK
    Fmoc-KCRGDK is a self-assembling peptide that can be used to prepare hydrogels and assist in drug delivery for immune checkpoint inhibitors. Fmoc-KCRGDK can be applied in cancer immunotherapy research.
    Fmoc-KCRGDK
  • HY-P10719
    Pepinh-MYD 1421052-89-2
    Pepinh-MYD is a MyD88 inhibitor that contains a domain sequence from MyD88 TIR and a protein transduction sequence, enabling it to penetrate the cell membrane. Pepinh-MYD interferes with MyD88-mediated TLR signaling pathways, thereby inhibiting related immune responses. It holds potential for studying the role of MyD88 in viral infections.
    Pepinh-MYD
  • HY-P10722
    Efpegerglucagon 2766774-81-4
    Efpegerglucagon is an Fc fragment of human immunoglobulin G4 (IgG4), formed as a disulfide-bonded dimer. One of the Fc chains is linked via a bifunctional maleimide-polyethylene glycol-aldehyde linker to a glucagon peptide analogue.
    Efpegerglucagon
  • HY-P10723
    IL-23R inhibitor peptide-1 2894052-23-2
    IL-23R inhibitor peptide-1 (comp 475) is an interleukin-23 receptor inhibitor, with an IC50 of 0.0069 μM.
    IL-23R inhibitor peptide-1
  • HY-P10728
    B7-33 1818415-56-3
    B7-33 is a single-chain relaxin mimetic. B7-33 is a selective relaxin receptor 1 (RXFP1) agonist. B7-33 binds to RXFP1 and preferentially activates thepERK pathway over cAMP in cells (with RXFP1 expression). B7-33 is an anti-fibrotic agent. B7-33 has cardioprotective effects.
    B7-33
  • HY-P10779
    flg22Pst 2268675-54-1
    flg22Pst is a peptide that can be derived Pseudomonas syringae pv. tabaci and serves as an effective elicitor for the plant immune system. flg22Pst can induce callose deposition in plants, trigger plant immune responses, and thereby assist plants in defending against pathogen invasion.
    flg22Pst
  • HY-P10796
    YARA peptide
    YARA peptide, a cell-penetrating peptide, is a MK2 inhibitor. YARA-loaded nanoparticles decreases the levels of inflammatory cytokines (IL-1β, IL-6, and TNF-α) in an ex vivo skin culture model. YARA peptide is promising for research of atopic dermatitis (AD).
    YARA peptide
  • HY-P10797
    TAT-N24
    TAT-N24 is a cell-permeable TAT peptide as a p55PIK signaling inhibitor. TAT-N24 is effective for corneal neovascularization (CNV) and ocular inflammation by inhibiting the HIF-1α/NF-κB signaling pathway in corneal suture (CS). TAT-N24 also inhibits corneal neovascularization.
    TAT-N24
  • HY-P10813
    ZLIRTLHEWY
    ZLIRTLHEWY is a potent peptide CD47/SIRPα interaction inhibitor. ZLIRTLHEWY is promising for research of cancers.
    ZLIRTLHEWY
Cat. No. Product Name / Synonyms Application Reactivity