2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-76225R
    Ammonium glycyrrhizinate (Standard) 53956-04-0
    Ammonium glycyrrhizinate (Standard) is the analytical standard of Ammonium glycyrrhizinate. This product is intended for research and analytical applications. Ammonium glycyrrhizinate (Monoammonium glycyrrhizinate) has various pharmacological actions such as anti-inflammatory, antiallergic, antigastriculcer, and antihepatitis activities.
    Ammonium glycyrrhizinate (Standard)
  • HY-76316R
    Bergaptol (Standard) 486-60-2
    Bergaptol (Standard) is the analytical standard of Bergaptol. This product is intended for research and analytical applications. Bergaptol is an inhibitor of debenzylation of the CYP3A4 enzyme with an IC50 of 24.92 μM. Recent studies have shown that it has anti-proliferative and anti-cancer properties.
    Bergaptol (Standard)
  • HY-76511S
    Verlukast-d6 153698-86-3
    Verlukast-d6 is a deuterium labeled Verlukast. Verlukast is a potent, selective, and orally active antagonist of leukotriene receptor. Verlukast has the potential for the research of asthma[1].
    Verlukast-d6
  • HY-79128S
    Fmoc-L-Lys (Boc)-OH-15N2 1217447-72-7
    Fmoc-L-Lys (Boc)-OH-15N2 is a 15N-labeled Fmoc-L-Lys (Boc)-OH (HY-79128). Fmoc-L-Lys (Boc)-OH is a lysine derivative.
    Fmoc-L-Lys (Boc)-OH-15N2
  • HY-A0015S
    Bepotastine-d6 besylate
    Bepotastine-d6(besylate) is deuterium labeled Bepotastine (besilate). Bepotastine besilate is a selective and orally active second-generation histamine H1 receptor antagonist, can suppress the expression of nerve growth factor (NGF). Bepotastine besilate has the potential for allergic rhinitis, allergic conjunctivitis and urticaria/pruritus research.
    Bepotastine-d6 besylate
  • HY-A0027A
    Fenspiride 5053-06-5
    Fenspiride, an orally active non-steroidal antiinflammatory agent, is an antagonist of H1-histamine receptor. Fenspiride inhibites phosphodiesterase 3 (PDE3), phosphodiesterase 4 (PDE4) and phosphodiesterase 5 (PDE5) activities with -log IC50 values of 3.44, 4.16 and approximately 3.8, respectively. Fenspiride can be used for the research of respiratory diseases.
    Fenspiride
  • HY-A0069A
    Doxylamine 469-21-6
    Doxylamine, a first generation antihistamine, is a histamine (H1) receptor antagonist. Doxylamine is also a local analgesic agent and effective hypnotic agent.
    Doxylamine
  • HY-A0069R
    Doxylamine (succinate) (Standard) 562-10-7
    Doxylamine (succinate) (Standard) is the analytical standard of Doxylamine (succinate). This product is intended for research and analytical applications. Doxylamine (succinate), a first generation antihistamine, is a histamine (H1) receptor antagonist. Doxylamine is also a local analgesic agent and effective hypnotic agent.
    Doxylamine (succinate) (Standard)
  • HY-A0069S
    Doxylamine-d5 succinate 1216840-94-6 ≥98.0%
    0
    Doxylamine-d5 succinate
  • HY-A0077A
    Perphenazine dihydrochloride 2015-28-3
    Perphenazine dihydrochloride is an orally active dopamine receptor and histamine-1 receptor antagonist, with Ki values of 0.56 nM (D2), 0.43 nM (D3), 6 nM (5-HT2A), respectively. Perphenazine dihydrochloride also binds to Alpha-1A adrenergic receptor. Perphenazine dihydrochloride inhibits cancer cell proliferation, and induces apoptosis. Perphenazine dihydrochloride can be used in the research of mental disease, cancer, inflammation.
    Perphenazine dihydrochloride
  • HY-A0111B
    Cefetamet hydrochloride 724438-16-8
    Cefetamet (Ro 15-8074) hydrochloride, an active cephalosporin compound, possesses abroad spectrum of activity against many aerobic gram-positiveand-negativeorganisms.
    Cefetamet hydrochloride
  • HY-A0129R
    Histamine phosphate (Standard) 51-74-1
    Histamine (phosphate) (Standard) is the analytical standard of Histamine (phosphate). This product is intended for research and analytical applications. Histamine phosphate is the agonist for histamine receptor and a vasodilator. Histamine phosphate affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities.
    Histamine phosphate (Standard)
  • HY-A0178A
    Isothipendyl hydrochloride 1225-60-1
    Isothipendyl hydrochloride (), an azaphenothiazine derivative, is a potent histamine 1 (H1) receptor antagonist.othipendyl is a primary metabolite.
    Isothipendyl hydrochloride
  • HY-A0191A
    Dexbrompheniramine maleate 2391-03-9
    Dexbrompheniramine maleate is an orally active H1 receptor antagonist. Dexbrompheniramine maleate is an antihistamine that reduces the effects of natural chemical histamine. Dexbrompheniramine maleate can be used for the research of hay fever and urticaria.
    Dexbrompheniramine maleate
  • HY-A0256R
    Clavulanic acid (Standard) 58001-44-8
    Clavulanic acid (Standard) is the analytical standard of Clavulanic acid. This product is intended for research and analytical applications. Clavulanic acid is a naturally occurring powerful bacterial β-lactamases inhibitor for research of infections caused by bacteria, including infections of the ears. Clavulanic acid is active against a wide spectrum of gram-positive and gram-negative bacterias[1].
    Clavulanic acid (Standard)
  • HY-A0273S
    Propyphenazone-d3 162935-29-7 ≥99.0%
    Propyphenazone-d3 is the deuterium labeled Propyphenazone. Propyphenazone is a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, Propyphenazone-based analogues as proagents and selective cyclooxygenase-2 inhibitors.
    Propyphenazone-d3
  • HY-B0006S
    Carvedilol-d3 1020719-25-8
    Carvedilol-d3 is the deuterium labeled Carvedilol. Carvedilol (BM 14190) is a non-selective β/α-1 blocker[1]. Carvedilol inhibits lipid peroxidation in a dose-dependent manner with an IC50 of 5 μM. Carvedilol is a multiple action antihypertensive agent with potential use in angina and congestive heart failure[2]. Carvedilol is an autophagy inducer that inhibits the NLRP3 inflammasome[3].
    Carvedilol-d3
  • HY-B0008S
    Sulindac-d3
    Sulindac-d3 is deuterium labeled Sulindac. Sulindac (MK-231) is a non-steroidal antiinflammatory agent, acts as a COX-2 inhibitor, and inhibits overexpression of COX-2.
    Sulindac-d3
  • HY-B0010S
    Formoterol-d6 1020719-45-2
    Formoterol-d6 is the deuterium labeled Formoterol. Formoterol ((±)Formoterol) is a potent, selective and long-acting β2-adrenoceptor agonist[1].
    Formoterol-d6
  • HY-B0012B
    Pamidronic acid sodium 89131-02-2
    Pamidronic acid sodium, the second-generation nitrogen-containing bisphosphonate, is an inhibitor of bone loss. Pamidronic acid sodium significantly inhibits subchondral bone loss in early osteoarthritis by upregulating the expression of osteoprotegerin in cartilage and subchondral bone, and inhibiting the expression of RANKL and MMP-9 in both tissues, as well as TLR-4 in cartilage, thereby alleviating cartilage degeneration. Additionally, Pamidronic acid sodium can inhibit the signaling of Wnt and β-catenin, and is applicable for research on osteoporosis and osteosarcoma.
    Pamidronic acid sodium
Cat. No. Product Name / Synonyms Application Reactivity