2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W010608
    2-Methyltetrahydrofuran-3-one 3188-00-9
    2-Methyltetrahydrofuran-3-one is a quorum sensing inhibitor that can inhibit biofilm formation by H. alvei. 2-Methyltetrahydrofuran-3-one is one of the volatile constituents of roasted coffee.
    2-Methyltetrahydrofuran-3-one
  • HY-W013168
    4-Nitrophenyl palmitate 1492-30-4 ≥98.0%
    4-Nitrophenyl palmitate (4-Nitrophenyl hexadecanoate; p-Nitrophenyl Palmitate) is a colorimetric lipase and esterase substrate. Upon enzymatic hydrolysis of 4-Nitrophenyl palmitate, 4-nitrophenol is released, which can be quantified by colorimetric detection at 410 nm as a measure of enzyme activity. 4-Nitrophenyl palmitate has been used to characterize the activity of various bacterial and mammalian enzymes, including Burkholderia and porcine pancreatic lipase.
    4-Nitrophenyl palmitate
  • HY-W014316
    5-Bromo-5-nitro-1,3-dioxane 30007-47-7 99.89%
    5-Bromo-5-nitro-1,3-dioxane, an antimicrobial compound, is effective against Gram-positive and Gram-negative bacteria and fungi, including yeast. 5-Bromo-5-nitro-1,3-dioxane inhibits enzyme activity and subsequent inhibition of microbial growth by the oxidation of essential protein thiol.
    5-Bromo-5-nitro-1,3-dioxane
  • HY-W015818
    2-Benzoxazolinone 59-49-4 ≥99.0%
    2-Benzoxazolinone is an anti-leishmanial agent with an LC50 of 40 μg/mL against L. donovani. A building block in chemical synthesis. 1,3-Benzoxazol-2(3H)-one derivatives have antimicrobial activity against a selection of Gram-positive, Gram-negative bacteria and yeasts. Derivatives as anti-quorum sensing agent.
    2-Benzoxazolinone
  • HY-W039454
    2,4-Dichlorobenzyl alcohol 1777-82-8 99.40%
    2,4-Dichlorobenzyl alcohol is a mild antiseptic, with a broad spectrum for bacterial and virus associated with mouth and throat infections.
    2,4-Dichlorobenzyl alcohol
  • HY-W040795
    N2-Acetylguanine 19962-37-9 99.69%
    N2-Acetylguanine is a C2-modified guanine. N2-Acetylguanine binds GR (guanine-guanine riboswitch) with an Kd value of 300 nM. N2-Acetylguanine modulate transcriptional termination. N2-Acetylguanine has the potential for the research of antimicrobial agent.
    N2-Acetylguanine
  • HY-W041324
    Glimepiride sulfonamide 119018-29-0 ≥98.0%
    Glimepiride sulfonamide is a intermediate, and can be used to synthesize Glimepiride (HY-B0104) (antidiabetic agent).
    Glimepiride sulfonamide
  • HY-W049970
    Carvacrol methyl ether 6379-73-3 99.98%
    Carvacrol methyl ether, a Carvacrol analog, can be isolated from plant volatile oil. Carvacrol methyl ether exhibits antibacterial activity.
    Carvacrol methyl ether
  • HY-W051164
    5-Hydroxyvanillin 3934-87-0 ≥98.0%
    5-Hydroxyvanillin is the product of the bacterial and fungal breakdown of ferulic acid, an abundant component in cell walls of found in many seed and leaves.
    5-Hydroxyvanillin
  • HY-W055872
    Erythromycylamine 26116-56-3
    Erythromycylamine is a macrolide antibiotic. Erythromycylamine has antibacterial activity against most Gram-positive cocci and M. catarrhalis.
    Erythromycylamine
  • HY-W089856
    Chlorobutanol hemihydrate 6001-64-5 ≥98.0%
    Chlorobutanol hemihydrate is an antimicrobial agent with oral activity, also possessing preservative effects. Chlorobutanol hemihydrate exhibits resistance to a variety of Gram-positive and Gram-negative bacteria, as well as several fungal spores and fungi, and is widely used in the food and cosmetics industries.
    Chlorobutanol hemihydrate
  • HY-W127493
    1-Hexacosanol 506-52-5 ≥98.0%
    1-Hexacosanol is a compound in the bioactive fraction of plant extracts that mediates insecticidal activity. 1-Hexacosanol has larvicidal activity and can inhibit the acetylcholinesterase activity of Culex quinquefasciatus, Aedes aegypti and Chironomus riparius, exerting neurotoxic effects.
    1-Hexacosanol
  • HY-W127841
    Citric acid-2,4-13C2 121633-50-9 98.00%
    Citric acid-2,4-13C2 is the 13C-labeled Citric acid (HY-N1428). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries.
    Citric acid-2,4-13C2
  • HY-W130965
    1-Formyl-beta-carboline 20127-63-3 ≥98.0%
    1-Formyl-beta-carboline is an alkaloid with inhibitory activity against Newcastle disease virus (NDV). 1-Formyl-beta-carboline can effectively inhibit different genotypes of NDV with IC50 values within 10 μM, and its inhibition rate is more than 90% at a concentration of 20 μM. 1-Formyl-beta-carboline mainly exerts its effects by inhibiting the adsorption and entry processes in the NDV life cycle. 1-Formyl-beta-carboline has been identified as a novel HN inhibitor that can directly interact with the NDV HN protein and affect the adsorption of NDV. 1-Formyl-beta-carboline also inhibits the entry of NDV by inhibiting the PI3K/Akt signaling pathway rather than the ERK pathway.
    1-Formyl-beta-carboline
  • HY-W195509
    Debrisoquin hydroiodide 1052540-65-4 99.84%
    Debrisoquin (hydroiodide) is the hydrochloride form of Debrisoquin (HY-B1624). Debrisoquin is a TMPRSS2 inhibitors that inhibits SARS-CoV-2 entry into human lung cell line by a TMPRSS2-depedent manner. Debrisoquin can be used for antiviral research.
    Debrisoquin hydroiodide
  • HY-W744966
    Mandipropamid 374726-62-2 99.22%
    Mandipropamid displays outstanding activity against late blight diseases of potato and tomato, combined with excellent efficacy on downy mildew diseases of grape and cucumber.
    Mandipropamid
  • HY-113225S3
    Guanosine triphosphate-15N5 dilithium
    Guanosine triphosphate-15N5 (GTP-15N5) dilithium is 15N labeled Guanosine triphosphate (HY-113225). Guanosine triphosphate is a native nucleotide. The derivatives of GTP may be used as specific inhibitors against COVID-19.
    Guanosine triphosphate-15N5 dilithium
  • HY-125818S3
    Cytidine-5'-triphosphate-13C9 dilithium 99.0%
    Cytidine-5'-triphosphate-13C9 (Cytidine triphosphate-13C9 dilithium; 5'-CTP-13C9) dilithium is 13C-labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii.
    Cytidine-5'-triphosphate-13C9 dilithium
  • HY-W001132R
    Indole (standard) 120-72-9
    Indole (Standard) is the analytical standard of Indole. This product is intended for research and analytical applications. Indole is an aromatic, heterocyclic, organic compound which widely distributed in the natural environment and can be produced by a variety of bacteria. Indole regulates various aspects of bacterial physiology, including spore formation, plasmid stability, resistance to drugs, biofilm formation, and virulence as an intercellular signal molecule.
    Indole (standard)
  • HY-W014589R
    2,4-Di-tert-butylphenol (Standard) 96-76-4
    2,4-Di-tert-butylphenol (Standard) is the analytical standard of 2,4-Di-tert-butylphenol (HY-W014589). This product is intended for research and analytical applications. 2,4-Di-tert-butylphenol (2,4-DTBP) is an orally active RXRα activator and a human estrogen receptor ligand with anti-inflammatory and antioxidant activities, which can induce apoptosis in tumor cells. 2,4-Di-tert-butylphenol can activate the RXRα subtype in LXRα/RXRα, PPARγ/RXRα, and hormone receptor β/RXRα. 2,4-Di-tert-butylphenol also has antiviral and antifungal activities, and has the potential to inhibit Aβ-induced neurotoxicity. 2,4-Di-tert-butylphenol can be used as an intermediate in the preparation of antioxidants and UV stabilizers, and is also used in the manufacture of pharmaceuticals and fragrances.
    2,4-Di-tert-butylphenol (Standard)
Cat. No. Product Name / Synonyms Application Reactivity