2. Gene
  3. Tfdp1 - transcription factor Dp 1 Gene

Tfdp1 - transcription factor Dp 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Dp1; Drtf1

Gene ID: 21781 | Gene type: protein coding

About Tfdp1

Summary

Enables DNA-binding transcription factor activity and cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of fat cell proliferation. Acts upstream of or within anoikis; epidermis development; and regulation of cellular macromolecule biosynthetic process. Located in cytoplasm and nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and retina. Orthologous to several human genes including TFDP1 (transcription factor Dp-1). [provided by Alliance of Genome Resources, Apr 2022]

Tfdp1 Products(32)

mRNA Protein Name
NM_001291765.2 NP_001278694.1 transcription factor Dp-1 isoform 1
NM_001291766.2 NP_001278695.1 transcription factor Dp-1 isoform 2
NM_001291768.2 NP_001278697.1 transcription factor Dp-1 isoform 2
NM_001358991.2 NP_001345920.1 transcription factor Dp-1 isoform 2
NM_001413797.1 NP_001400726.1 transcription factor Dp-1 isoform 2
NM_001413798.1 NP_001400727.1 transcription factor Dp-1 isoform 2
NM_001413799.1 NP_001400728.1 transcription factor Dp-1 isoform 2
NM_001413800.1 NP_001400729.1 transcription factor Dp-1 isoform 2
NM_001413801.1 NP_001400730.1 transcription factor Dp-1 isoform 3
NM_001413802.1 NP_001400731.1 transcription factor Dp-1 isoform 2
NM_001413803.1 NP_001400732.1 transcription factor Dp-1 isoform 2
NM_001413804.1 NP_001400733.1 transcription factor Dp-1 isoform 4
NM_001413805.1 NP_001400734.1 transcription factor Dp-1 isoform 5
NM_001413806.1 NP_001400735.1 transcription factor Dp-1 isoform 2
NM_001413807.1 NP_001400736.1 transcription factor Dp-1 isoform 2
NM_001413808.1 NP_001400737.1 transcription factor Dp-1 isoform 2
NM_001413809.1 NP_001400738.1 transcription factor Dp-1 isoform 2
NM_001413810.1 NP_001400739.1 transcription factor Dp-1 isoform 2
NM_001413811.1 NP_001400740.1 transcription factor Dp-1 isoform 2
NM_001413812.1 NP_001400741.1 transcription factor Dp-1 isoform 2
NM_001413813.1 NP_001400742.1 transcription factor Dp-1 isoform 2
NM_001413814.1 NP_001400743.1 transcription factor Dp-1 isoform 2
NM_001413815.1 NP_001400744.1 transcription factor Dp-1 isoform 6
NM_001413816.1 NP_001400745.1 transcription factor Dp-1 isoform 2
NM_001413817.1 NP_001400746.1 transcription factor Dp-1 isoform 2
NM_001413818.1 NP_001400747.1 transcription factor Dp-1 isoform 2
NM_001413819.1 NP_001400748.1 transcription factor Dp-1 isoform 1
NM_001413820.1 NP_001400749.1 transcription factor Dp-1 isoform 2
NM_001413821.1 NP_001400750.1 transcription factor Dp-1 isoform 2
NM_001413822.1 NP_001400751.1 transcription factor Dp-1 isoform 1
NM_001413823.1 NP_001400752.1 transcription factor Dp-1 isoform 1
NM_009361.4 NP_033387.1 transcription factor Dp-1 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
14667810 MGI
enables cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
15448153 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11331592 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within anoikis IDA
IDA: Inferred from direct assay
14667810 MGI
acts upstream of or within epidermis development IMP
IMP: Inferred from mutant phenotype
15448153 MGI
involved in negative regulation of fat cell proliferation IMP
IMP: Inferred from mutant phenotype
20176812 MGI
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
11331592 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
7797074 MGI
acts upstream of or within regulation of DNA biosynthetic process IMP
IMP: Inferred from mutant phenotype
15448153 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
14667810 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
25940086 MGI
located in nucleus IDA
IDA: Inferred from direct assay
10082561 MGI
part of transcription regulator complex IDA
IDA: Inferred from direct assay
10082561 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor Dp-1

DRTF1-polypeptide 1

E2F dimerization partner 1

cell cycle regulatory transcription factor DP1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14417 TFDP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21066 Tfdp1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27583 Tfdp1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tfdp1 NCBI NCBI:7027