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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (7743):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W088629S
    (R)-3-Aminopiperidine-2,6-dione-d hydrochloride
    (R)-3-Aminopiperidine-2,6-dione-d hydrochloride is the deuterium labeled (R)-3-Aminopiperidine-2,6-dione hydrochloride[1].
    (R)-3-Aminopiperidine-2,6-dione-d hydrochloride
  • HY-113603S
    Tildacerfont-d8
    Tildacerfont-d8 (SPR001-d8) is a deuterium labeled Tildacerfont (HY-113603). Tildacerfont is a potent and orally active corticotrophin-releasing factor type 1 (CRF1) receptort antagonis. Tildacerfont effectively reduces adrenocorticotropic hormone (ACTH) and adrenal androgen levels. Tildacerfont has favourable safety profile. Tildacerfont can be used for researching congenital adrenal hyperplasia.
    Tildacerfont-d<sub>8</sub>
  • HY-W157316S
    1,4-bUtanedithiol-d8
    1,4-bUtanedithiol-d8 is the deuterium labeled 1,4-bUtanedithiol[1].
    1,4-bUtanedithiol-d<sub>8</sub>
  • HY-B0678S1
    Metaxalone-d6
    Metaxalone-d6 is deuterium labeled Metaxalone. Metaxalone (AHR438; NSC170959) is an FDA-approved muscle relaxant. Metaxalone acts mainly on the central nervous system and achieves muscle relaxation by inhibiting polysynaptic reflex arcs. In addition, Metaxalone is an inhibitor of MAO-A, which has anti-inflammatory and antioxidant effects. Metaxalone inhibits IL-1β-induced inflammatory phenotype, modulates NF-κB and other related signaling pathways, and decreases MAO-A expression and activity in IL-1β-treated microglia.
    Metaxalone-d<sub>6</sub>
  • HY-W011038S
    1-Hexadecylpyridin-1-ium bromide-d5
    1-Hexadecylpyridin-1-ium bromide-d5 is the deuterium labeled 1-Hexadecylpyridin-1-ium bromide[1].
    1-Hexadecylpyridin-1-ium bromide-d<sub>5</sub>
  • HY-146773S
    7α-Hydroxy-3-oxocholest-4-enoic acid-d3
    ≥99.0%
    7α-Hydroxy-3-oxocholest-4-enoic acid-d3 is deuterium labeled 7α-Hydroxy-3-oxocholest-4-enoic acid.
    7α-Hydroxy-3-oxocholest-4-enoic acid-d<sub>3</sub>
  • HY-B0946S3
    Sulfamonomethoxine-d3-1
    Sulfamonomethoxine-d3-1 is the deuterium labeled Sulfamonomethoxine (HY-B0946). Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity.
    Sulfamonomethoxine-d<sub>3</sub>-1
  • HY-Z5058S
    (3R,5S)-Fluvastatin-d7 sodium
    (3R,5S)-Fluvastatin-d7 (sodium) is the deuterium labeled (3R,5S)-Fluvastatin sodium[1].
    (3R,5S)-Fluvastatin-d<sub>7</sub> sodium
  • HY-N0060S1
    Ferulic acid-13C3
    98.3%
    Ferulic acid-13C3 is the 13C-labeled Ferulic acid. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.
    Ferulic acid-<sup>13</sup>C<sub>3</sub>
  • HY-W012497S
    N-Acetyl-D-methionine-d4
    N-Acetyl-D-methionine-d4 is the deuterium labeled N-Acetyl-D-methionine[1]. N-Acetyl-D-methionine is a Methionine (HY-13694) derivative[2].
    N-Acetyl-D-methionine-d<sub>4</sub>
  • HY-B1260S2
    Cetrimonium-d3 bromide
    Cetrimonium-d3 (bromide) is the deuterium labeled Cetrimonium bromide[1].
    Cetrimonium-d<sub>3</sub> bromide
  • HY-13690S3
    Mitotane-13C12
    Mitotane-13C12 (2,4′-DDD-13C12) is 13C labeled Mitotane. Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions.
    Mitotane-<sup>13</sup>C<sub>12</sub>
  • HY-N0229S14
    L-Alanine-15N,d4
    L-Alanine-15N,d4 is the deuterium and 15N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
    L-Alanine-<sup>15</sup>N,d<sub>4</sub>
  • HY-B0684S
    Iopamidol-d8
    Iopamidol-d8 (B-15000-d8) is the deuterium labeled Iopamidol. Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast[1].
    Iopamidol-d<sub>8</sub>
  • HY-132440S
    Iso Rizatriptan-d6
    Iso Rizatriptan-d6 is the deuterium labeled Iso Rizatriptan[1].
    Iso Rizatriptan-d<sub>6</sub>
  • HY-B1856S
    Haloxyfop-d4
    Haloxyfop-d4 is deuterium labeled Haloxyfop. Haloxyfop is an aryloxyphenoxypropionic acid herbicide and is widely used in grass weeds in broad-leaf crops. Haloxyfop inhibits the acetyl coenzyme A carboxylase (EC 6.4.1.2) from corn seedling chloroplasts with an IC50 of 0.5 μM, but has no effect on this enzyme in pea.
    Haloxyfop-d<sub>4</sub>
  • HY-B0141S7
    rel-Estradiol-13C6
    rel-Estradiol-13C6 is the sup>13C-labeled rel-Estradiol.
    rel-Estradiol-<sup>13</sup>C<sub>6</sub>
  • HY-W048482S3
    rU Phosphoramidite-15N2
    rU Phosphoramidite-15N2 (DMT-2'O-TBDMS-rU phosphoramidite-15N2) is 15N labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
    rU Phosphoramidite-<sup>15</sup>N<sub>2</sub>
  • HY-B0656AS1
    Rabeprazole-d3 sodium
    Rabeprazole-d3 sodium the deuterium labeled Rabeprazole sodium (HY-B0656A). Rabeprazole sodium (LY307640 sodium) is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole sodium induces apoptosis. Rabeprazole sodium acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an b>IC50 of 0.3 μM. Rabeprazole sodium can be used for the research of gastric ulcerations and gastroesophageal reflux.
    Rabeprazole-d<sub>3</sub> sodium
  • HY-146776S
    5β,6β-Epoxycholestanol-d7
    99.0%
    5β,6β-Epoxycholestanol-d7 is deuterium labeled 5β,6β-Epoxycholestanol.
    5β,6β-Epoxycholestanol-d<sub>7</sub>