2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W004282S1
    Undecanoic acid-d3
    Undecanoic acid-d3 (Undecanoate-d3) is the deuterium labeled Undecanoic acid (HY-W004282). Undecanoic acid is a monocarboxylic acid with antifungal property. Undecanoic acid inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum.
    Undecanoic acid-d<sub>3</sub>
  • HY-167911
    Cidofovir sodium
    Cidofovir sodium is an acyclic monophosphate nucleotide analogue and CMV inhibitor with antiviral activity. Cidofovir sodium inhibits cytomegalovirus (CMV) replication by selectively inhibiting viral DNA polymerase. Cidofovir sodium induces apoptosis and can be used in studies of AIDS cytomegalovirus retinitis, herpes, and cancer. Cidofovir sodium also has anti-orthopoxvirus and anti-variola activities.
    Cidofovir sodium
  • HY-E70329
    P-Hydroxybenzoate hydroxylase, native microorganism
    P-Hydroxybenzoate hydroxylase, native microorganism is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible.
    P-Hydroxybenzoate hydroxylase, native microorganism
  • HY-100807S2
    Quinolinic acid-13C4,15N
    Quinolinic acid-13C4, 15N is an isotopic labeled Quinolinic acid (HY-100807). Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist and has the potential of mediating NMDA neuronal damage and dysfunction.
    Quinolinic acid-<sup>13</sup>C<sub>4</sub>,<sup>15</sup>N
  • HY-N9944R
    3-Oxo-4,6-choladien-24-oic acid (Standard)
    3-Oxo-4,6-choladien-24-oic acid (Standard) is the analytical standard of 3-Oxo-4,6-choladien-24-oic acid. This product is intended for research and analytical applications. 3-Oxo-4,6-choladien-24-oic acid is an endogenous metabolite. 3-Oxo-4,6-choladien-24-oic acid exsists in the urine of patients with hepatobiliary disease[1].
    3-Oxo-4,6-choladien-24-oic acid (Standard)
  • HY-125863C
    Glucose-6-phosphate dehydrogenase, Bacillus sp.
    Glucose-6-phosphate dehydrogenase, Bacillus sp. catalyzes the conversion of glucose-6-phosphate into 6-phosphogluconolactone, and produces reduced nicotinamide adenine dinucleotide phosphate (NADPH) and ribose-5-phosphate in this process. Glucose-6-phosphate dehydrogenase, Bacillus sp. can be used in research about diabetic complications.
    Glucose-6-phosphate dehydrogenase, Bacillus sp.
  • HY-N2041S1
    Myristic acid-d2
    Myristic acid-d2 is the deuterium labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.
    Myristic acid-d<sub>2</sub>
  • HY-W017158R
    Melilotic acid (Standard)
    Vorapaxar (sulfate) (Standard) is the analytical standard of Vorapaxar (sulfate). This product is intended for research and analytical applications. Vorapaxar sulfate (SCH 530348 sulfate), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist (Ki=8.1 nM). Vorapaxar sulfate inhibits thrombin receptor-activating peptide (TRAP)-induced platelet aggregation in a dose-dependent manner.
    Melilotic acid (Standard)
  • HY-136871
    Decarestrictin A1
    Decarestrictine A1 is a fungal metabolite that has been found in Penicillium.
    Decarestrictin A1
  • HY-18341F
    Biotin-(L-Thyroxine)
    Biotin-(L-Thyroxine) is the biotinylated L-Thyroxine (HY-18341). L-Thyroxine is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from Biotin-(L-Thyroxine) (T4).
    Biotin-(L-Thyroxine)
  • HY-B1204S4
    Histamine-15N3
    Histamine-15N3 is the 15N3-labeled Histamine (HY-B1204). Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter.
    Histamine-<sup>15</sup>N<sub>3</sub>
  • HY-E70412A
    Galactose 1-dehydrogenase, pseudomonas fluorescens
    Galactose 1-dehydrogenase, pseudomonas fluorescens is a dehydrogenase expressed in Pseudomonas fluorescens. Galactose 1-dehydrogenase, pseudomonas fluorescens catalyzes the oxidation of L-arabinose and D-galactose using NADP+/NAD+ as a cofactor. Galactose 1-dehydrogenase, pseudomonas fluorescens can be used in diagnostic tests to measure total galactose content and can also act as a biocatalyst for producing galacturonic acid salts.
    Galactose 1-dehydrogenase, pseudomonas fluorescens
  • HY-167740
    Glycerophosphoinositol (lysine)
    Glycerophosphoinositol (GroPIns) lysine is a phospholipid metabolite that possesses anti-dandruff, anti-inflammatory, and anti-aging activities; it significantly suppresses UVB-induced PGE secretion in NHEK keratinocytes.
    Glycerophosphoinositol (lysine)
  • HY-145542S
    Isovalerylcarnitine-d9 chloride
    Isovalerylcarnitine-d9 (chloride) is the deuterium labeled Isovalerylcarnitine (chloride)[1]. Isovalerylcarnitine chloride, a product of the catabolism of L-leucine, is a potent activator of the Ca2+-dependent proteinase (calpain) of human neutrophils[2].
    Isovalerylcarnitine-d<sub>9</sub> chloride
  • HY-127012
    H-0104 dihydrochloride
    H-0104 dihydrochloride is a ROCK inhibitor with significant intraocular pressure (IOP)-lowering activity. H-0104 dihydrochloride effectively reduces IOP when administered to monkey eyes. There may not be a direct relationship between the Iop-lowering effect of H-0104 dihydrochloride and ROCK inhibition.
    H-0104 dihydrochloride
  • HY-W040948S
    2-Ethylpyrazine-d5
    2-Ethylpyrazine-d5 is the deuterium labeled 2-Ethylpyrazine[1]. 2-Ethylpyrazine is an endogenous metabolite.
    2-Ethylpyrazine-d<sub>5</sub>
  • HY-120109
    13-HODE methyl ester
    13-HODE methyl ester, a racemic mixture of 13(R)-HODE methyl ester and 13(S)-HODE methyl ester, is a 15-lipoxygenase metabolite of Linoleic acid.
    13-HODE methyl ester
  • HY-14608S10
    L-Glutamic acid-13C2
    L-Glutamic acid-13C2 is the 13C labeled L-Glutamic acid[1]. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals[2].
    L-Glutamic acid-<sup>13</sup>C<sub>2</sub>
  • HY-W012658R
    2-Methylacetophenone (Standard)
    2-Methylacetophenone (Standard) is the analytical standard of 2-Methylacetophenone. This product is intended for research and analytical applications. 2-Methylacetophenone is an endogenous metabolite.
    2-Methylacetophenone (Standard)
  • HY-W018772S5
    D-Ribose-13C-4
    		≥99.0%
    D-Ribose-13C-4 is the 13C labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein glyca
    D-Ribose-<sup>13</sup>C-4
Cat. No. Product Name / Synonyms Application Reactivity