2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P1320A
    [Nphe1]Nociceptin(1-13)NH2 TFA
    [Nphe1]Nociceptin(1-13)NH2, a novel nociceptin/orphanin FQ (NC) endogenous ligand, is a selective and competitive ociceptin receptor antagonist without any residual agonist activity. [Nphe1]nociceptin(1-13)NH2?binds selectively to recombinant nociceptin receptors (pKi=8.4) and antagonizes the inhibitory effects of nociceptin on cyclic AMP accumulation in CHO cells (pA2=6.0). [Nphe1]Nociceptin(1-13)NH2 has the potential to act as an analgesic agent.
    [Nphe1]Nociceptin(1-13)NH2 TFA
  • HY-P1398A
    Compstatin control peptide TFA
    Compstatin control peptide TFA is a negative control of Compstatin (HY-P1036). Compstatin is a potent complement system C3 inhibitor.
    Compstatin control peptide TFA
  • HY-P1426A
    AmmTX3 TFA
    AmmTX3 TFA is a peptide toxin that can be isolated from the venom of the scorpion Androctonus mauretanicus. AmmTX3 TFA is specific blocker of Kv4 channel. AmmTX3 TFA inhibits the A-type K+ current (Ki: 131 nM).
    AmmTX3 TFA
  • HY-P1489B
    OVA Peptide(257-264) acetate salt
    OVA Peptide(257-264) acetate salt is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide can be from ovalbumin presented by the class I MHC molecule, H-2Kb.
    OVA Peptide(257-264) acetate salt
  • HY-P1535A
    Secretin, porcine TFA
    Secretin, porcine TFA (Porcine secretin TFA) is a 27-amino acid peptide, acting on pancreatic acinar cells and ductal epithelial cells stimulating the production of bicarbonate rich fluid.
    Secretin, porcine TFA
  • HY-P1548B
    β-CGRP, human acetate
    β-CGRP, human acetate (Human β-CGRP acetate) is one of calcitonin peptides, acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells.
    β-CGRP, human acetate
  • HY-P1591A
    N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA 2918767-97-0
    N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA (For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA) is a formyl peptide receptor (FPR) agonist.
    N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA
  • HY-P1624A
    Teduglutide TFA
    Teduglutide TFA is a dipeptidyl peptidase IV resistant glucagon-like peptide 2 (GLP-2) analogue. Teduglutide TFA can activate the expression of nuclear receptor subfamily 4 group a member 1 (NR4a1)/nur77 and intestinal FXR signaling in human hepatic stellate cells, thereby improving liver inflammation and fibrosis in mice with sclerosing cholangitis. Teduglutide TFA can alleviate intestinal dysfunction in mice, improve lung injury, alleviate obesity related neuroinflammation and cell apoptosis.
    Teduglutide TFA
  • HY-P1746A
    Protein Kinase C (19-31) (TFA)
    Protein Kinase C (19-31) TFA, a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31), is used as protein kinase C substrate peptide for testing the protein kinase C activity.
    Protein Kinase C (19-31) (TFA)
  • HY-P1773A
    IGF-I (30-41) (TFA)
    IGF-I (30-41) (TFA) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions).
    IGF-I (30-41) (TFA)
  • HY-P1777A
    IGF-I (24-41) (TFA)
    IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) TFA is amino acids 24 to 41 fragment of IGF-I. IGF-I TFA, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I TFA is partly responsible for systemic growth hormone (GH) activities. IGF-I TFA has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) TFA regulates somatic growth and behavioral development.
    IGF-I (24-41) (TFA)
  • HY-P1826A
    CLIP (86-100) (TFA)
    CLIP (86-100) TFA is amino acids 86 to 100 fragment of class II-associated invariant chain peptide (CLIP). CLIP is a small self-peptide and cleavage product of the invariant chain that resides in the HLA-II antigen binding groove and is believed to play a critical role in the assembly and transport of MHC class II alphabetaIi complexes through its interaction with the class II peptide-binding site.
    CLIP (86-100) (TFA)
  • HY-P1889A
    Bim BH3, Peptide IV TFA
    Bim BH3, Peptide IV TFA is a 26-residue peptide from BH3-only protein Bim, which belongs to the pro-apoptotic group of the Bcl-2 family of proteins.
    Bim BH3, Peptide IV TFA
  • HY-P1924A
    IRBP(651-670) human, mouse TFA
    IRBP(651-670) human, mouse (TFA) represents the amino acid sequence from positions 651 to 670 of the interphotoreceptor retinoid binding protein (IRBP). IRBP(651-670) human, mouse (TFA) can be used to induce experimental autoimmune uveitis.
    IRBP(651-670) human, mouse TFA
  • HY-P2015A
    Diacetylsplenopentin hydrochloride 122402-38-4
    Diacetylsplenopentin (BCH 069) hydrochloride is an antiviral agent, and protects guinea pigs from foot-and-mouth disease (FMD) infection. Berlopentin has immunostimulatory properties.
    Diacetylsplenopentin hydrochloride
  • HY-P2194A
    AtPep3 TFA
    AtPep3 TFA is a hormone-like peptide. AtPep3 TFA can enhance salinity tolerance of plants and inhibits the salt-induced bleaching of chlorophyll in seedlings.
    AtPep3 TFA
  • HY-P2291A
    Beta-defensin 103 isoform X1, pig TFA
    Beta-defensin 103 isoform X1, pig TFA is an antimicrobial peptide found in different living organisms, involved in the first line of defense in their innate immune response against pathogens.
    Beta-defensin 103 isoform X1, pig TFA
  • HY-P2321A
    TRAP-6 amide TFA 1426807-16-0
    TRAP-6 amide TFA is a PAR-1 thrombin receptor agonist peptide.
    TRAP-6 amide TFA
  • HY-P2355A
    {Boc}-Phe-Leu-Phe-Leu-Phe TFA
    {Boc}-Phe-Leu-Phe-Leu-Phe TFA is a formyl peptide receptor (FPR) family antagonist that preferentially inhibits activity triggered through the formyl peptide receptor.
    {Boc}-Phe-Leu-Phe-Leu-Phe TFA
  • HY-P2358A
    PSMα3 TFA
    PSMα3 TFA is a peptide for manipulating DCs to become tolerogenic for DC vaccination strategies. PSMα3 TFA penetrates and modulates human monocyte-derived DCs by altering the TLR2- or TLR4-induced maturation, inhibiting pro- and anti-inflammatory cytokine production and reducing antigen uptake. PSMα3 TFA is an important toxin released by the most virulent strains of methicillin-resistant Staphylococcus aureus (MRSA).
    PSMα3 TFA
Cat. No. Product Name / Synonyms Application Reactivity