2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

PDF 93.1 MB

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N12399
    Aplithianines A 3027425-38-0
    Aplithianines A is a potent inhibitor against J-PKAcα with an IC50 of 1 μM , and inhibits wild-type PKA with an IC50 of 84 nM. Aplithianines A inhibits J-PKAcα catalytic activity by competitively binding to the ATP pocket.
    Aplithianines A
  • HY-N12429
    Marstenacisside F1 2902666-68-4
    Marstenacisside F1 (compound 1) is a polyoxypregnanoside with anti-inflammatory activity isolated from Marsdenia tenacissima. Marstenacisside F1 inhibits lipopolysaccharide-induced nitric oxide (NO) production in RAW 264.7 cells and is a derivative of Tenacigenin B.
    Marstenacisside F1
  • HY-N12443
    Antioxidant agent-18 143016-73-3
    Antioxidant agent-18 (compound 5) is a flavonol glycoside with antioxidant activity isolated from Ginkgo biloba. Antioxidant agent-18 scavenges DPPH radicals (IC50: 15.8 μM) and reduces cytochrome c (IC50: 14.7 μM).
    Antioxidant agent-18
  • HY-N12467
    24-Methylcholesterol 23929-42-2
    24-Methylcholesterol is a trans-ferulate ester that can be isolated from rice bran. 24-Methylcholesterol significantly inhibited TPA-induced inflammation.
    24-Methylcholesterol
  • HY-N12478
    Ainsliadimer A 1039431-94-1
    Ainsliadimer A is a sesquiterpene lactone dimer with an unusual carbon skeleton. Ainsliadimer A can be obtained from from Ainsliaea macrocephala. Ainsliadimer A inhibits the production of nitric oxide in cells stimulated by LPS.
    Ainsliadimer A
  • HY-N12521
    (3β,24S)-3-Hydroxystigmast-5-en-7-one 145163-97-9
    (3β,24S)-3-Hydroxystigmast-5-en-7-one (Compound 31) is a compound that can be isolated from Lindera akoensis . (3β,24S)-3-Hydroxystigmast-5-en-7-one has anti-inflammatory activity.
    (3β,24S)-3-Hydroxystigmast-5-en-7-one
  • HY-N12541
    Morunigrol C 1174134-94-1
    Morunigrol C is a compound that can be isolated from the barks of Morus nigra.
    Morunigrol C
  • HY-N12615
    Anti-inflammatory agent 75
    Anti-inflammatory agent 75
  • HY-N12647
    cis-Hinkiresinol 230292-85-0
    cis-Hinkiresinol is a bioactive constituent of Rhizoma anemarrhenae. Rhizoma anemarrhenae is reprted to have anti-pathogenic microorganism, hypoglycemic effects, anti-inflammatory, antipyretic effects and anti-platelet aggregation.
    cis-Hinkiresinol
  • HY-N12648
    Anemarsaponin E1 1276608-19-5
    Anemarsaponin E1 can be isolated from Guizhi-Shaoyao-Zhimu decoction (GSZD), and can be used for research of rheumatoid arthritis (RA), gout, osteoarthritis, etc.
    Anemarsaponin E1
  • HY-N12649
    Timosaponin E2 222018-47-5
    Timosaponin E2 is an antiinflammatory agent, and inhibits active oxygen production.
    Timosaponin E2
  • HY-N12694
    3-O-Methylellagic acid-4′-O-α-L-rhamnopyranoside 51768-39-9
    3-O-Methylellagic acid-4′-O-α-L-rhamnopyranoside is an ellagic acid glycoside compound that can be isolated from the stem bark of Aphananthe aspera and can be used for the research of inflammation and pain.
    3-O-Methylellagic acid-4′-O-α-L-rhamnopyranoside
  • HY-N12703
    N-Acetyldopamine dimmers A 1519015-73-6
    N-Acetyldopamine dimmers A (Compound (+)-2) can be isolated from the cast-off shell of the cicada of Cryptotympana sp. N-Acetyldopamine dimmers A increases collagen and α-SMA expression.
    N-Acetyldopamine dimmers A
  • HY-N12707
    Kadsurenin C 145722-88-9
    Kadsurenin C (compound 1) is a neolignan that can be isolated from the aerial part of Piper kadsura with anti-inflammation activity. Kadsurenin C exhibits significant PAF (Platelet Activating Factor) antagonistic activity with IC50 value of 5.1 μM.
    Kadsurenin C
  • HY-N12726
    Halociline 2977255-36-8
    Halociline, a derivative of alkaloids, that can be isolated from the marine fungus Penicillium griseofulvum. Halociline targets MAPK1, MMP-9, and PIK3CA in gastric cancer cells, potentially mediated by diverse pathways including cancer, lipid metabolism, atherosclerosis, and EGFR tyrosine kinase inhibitor resistance. Halociline possesses antimicrobial, antioxidant and biofilm inhibitory activities.
    Halociline
  • HY-N12734
    Pebrellin 13509-93-8
    Pebrellin is a flavonoid that can be isolated from Mentha × piperita leaves.
    Pebrellin
  • HY-N12737
    15-epi-Danshenol A 216987-13-2
    15-epi-Danshenol A is a diterpenoid with an immune-modulating activity. 15-epi-Danshenol A shows inhibitory effect on B lymphoblasts cells in a concentration-dependent manner.
    15-epi-Danshenol A
  • HY-N12742
    Tamarixetin 3-O-β-d-apiofuranosyl-(1 → 2)-β-d-galactopyranoside
    Tamarixetin 3-O-β-d-apiofuranosyl-(1 → 2)-β-d-galactopyranoside (compound 4) is an inhibitor of collagenase and elastase with potential anti-inflammatory activity. Tamarixetin 3-O-β-d-apiofuranosyl-(1 → 2)-β-d-galactopyranoside can be isolated from the methanol extract of the Balkan endemic species Astragalus thracicus Griseb.
    Tamarixetin 3-O-β-d-apiofuranosyl-(1 → 2)-β-d-galactopyranoside
  • HY-N12743
    Farobin A 1245447-08-8
    Farobin A is a natural compound with antibacterial, antioxidant and anti-inflammatory activities. Farobin A against Streptococcus mutans ATCC 25175 and Streptococcus sobrinus ATCC 33478. Farobin A shows anti-inflammatory activity on cytokine IL-6 and TNF-α.
    Farobin A
  • HY-N12761
    Penpaxilloids A
    Penpaxilloids A (Compound 1) is a non-competitive inhibitor of protein tyrosine phosphatase 1B (PTP1B) with an IC50 value of 8.60 μM. Penpaxilloids A can be isolated from the fungus Penicillium sp. ZYX-Z-143. Penpaxilloids A is also an α-glucosidase (α-glucosidase) inhibitor with anti-inflammatory activity.
    Penpaxilloids A
Cat. No. Product Name / Synonyms Application Reactivity