1. Inflammation/Immunology

Inflammation/Immunology

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N12000
    Aquilarone C 1404479-46-4
    Aquilarone C is a chromone derivative with anti-inflammatoryeffects.
    Aquilarone C
  • HY-N12042
    Taxamairin B 110300-77-1
    Taxamairin B is a potent anti-inflammatory agent. Taxamairin B decreases proinflammatory cytokines (TNF-α, IL-1β and IL-6) expression and the production of NO and ROS in LPS-induced RAW264.7 cells. Taxamairin B exhibits significant protective effects in LPS-induced acute lung injury in mice.
    Taxamairin B
  • HY-N12047
    Schineolignin C 1352185-28-4
    Schineolignin C is a Lignan that can be isolated from the fruit of schisandra chinensis. schisandra chinensis has antihepatitis, antitumor, and anti-HIV-1 activities.
    Schineolignin C
  • HY-N12081
    Oxyresveratrol 4-O-β-D-glucopyranoside 863329-68-4
    Oxyresveratrol 4-O-β-D-glucopyranoside (compound 3) is a natural product that can be obtained from the root bark of Morus atropurpurea. Oxyresveratrol 4-O-β-D-glucopyranoside has potential in studies of diabetes, arthritis, rheumatism, cough and headache.
    Oxyresveratrol 4-O-β-D-glucopyranoside
  • HY-N12108
    Forphenicine 57784-96-0
    Forphenicine is a bacterial metabolite that is found in S. fulvoviridis and an inhibitor of alkaline phosphatase. Forphenicine inhibits the growth of HL-60 leukemia cells at 10 µM. Forphenicine also increases survival in a guinea pig model of experimental autoimmune encephalomyelitis (EAE).
    Forphenicine
  • HY-N12121
    Piperundecalidine 88660-11-1
    Piperundecalidine is an amide alkaloids that can be purified from Piper longum L. Piperundecalidine shows various biological properties, such as anti-inammatory, analgesic, anti-amoebic, anti-depressant, hepatoprotective,etc..
    Piperundecalidine
  • HY-N12126
    Sydowinin B 58450-00-3
    Sydowinin B (MS-347b) is a active compound and can be isolated from A. sydowii. Sydowinin B shows has immunosuppressant activity.
    Sydowinin B
  • HY-N12155
    (2,4,6-Trichloro-3-hydroxy-5-methoxyphenyl)methyl β-D-glucopyranoside 2839363-14-1
    (2,4,6-Trichloro-3-hydroxy-5-methoxyphenyl)methyl β-D-glucopyranoside (Compound 1) is a chlorophenyl glycoside that can be isolated from Lilium regale. Lilium regale is used for research of lung ailments.
    (2,4,6-Trichloro-3-hydroxy-5-methoxyphenyl)methyl β-D-glucopyranoside
  • HY-N12186
    Sibiricine 24181-66-6
    Sibiricine (Compound 8) is an isoquinoline alkaloid derived from the medicinal plant Corydalis crispa. Sibiricine has significant anti-inflammatory activity on TNF-α production by LPS-activated THP-1 cells.
    Sibiricine
  • HY-N12235
    Sarglaroids F
    Sarglaroids F (compound 6) is an anti-inflammatory agent isolated from the roots of Grass Coral. Sarglaroids F inhibits LPS/ATP-induced IL-1β release by affecting K+ efflux and reducing Caspase-1(P20) levels. Sarglaroids F is not cytotoxic to RAW264.7 cells.
    Sarglaroids F
  • HY-N12249
    7-Deoxy-trans-dihydronarciclasine 145987-74-2
    7-Deoxy-trans-dihydronarciclasine, an alkaloid, is a tobacco mosaic virus (TMV) inhibitor (IC50: 1.80 μM). 7-Deoxy-trans-dihydronarciclasine is an anti-neuroinflammatory agent. 7-Deoxy-trans-dihydronarciclasine decreases the and APP levels in the cerebral cortex of Tg2576 mice.
    7-Deoxy-trans-dihydronarciclasine
  • HY-N12265
    Versicolactone B 108885-62-7
    Versicolactone B is a sesquiterpene that can be isolated from Viola yedoensis. Versicolactone B exhibits anti-complement activity against the classical pathway and the alternative pathway.
    Versicolactone B
  • HY-N12287
    Curcapicycloside 229971-57-7
    Curcapicycloside (Pilosidine), a norlignan glucoside, exhibits antibacterial activity against Escherichia coli.
    Curcapicycloside
  • HY-N12295
    Ciwujianoside D1 114912-35-5
    Ciwujianoside D1 is a natural product that can inhibit histamine release induced by anti-immunoglobulin E from rat peritoneal mast cells.
    Ciwujianoside D1
  • HY-N12323
    6′-Galactosyllactose 32581-31-0
    6′-Galactosyllactose is the main oligosaccharide that makes up galactose, a component of human milk. 6′-Galactosyllactose can synthesize human milk oligosaccharides and synthetic galactosyllactose with 3′-Galactosyllactose and 4′-Galactosyllactose, and reduce inflammation in human T84, NCM-460 and H4 cells and intestinal tissues.
    6′-Galactosyllactose
  • HY-N12347
    α-Glucosidase-IN-37 917078-12-7
    α-Glucosidase-IN-37 (Compound 11) moderately inhibits LPS-induced NO production with an IC50 value of 23.7 μM in macrophages. α-Glucosidase-IN-37 has weak inhibitory activity against α-Glucosidase.
    α-Glucosidase-IN-37
  • HY-N12378
    β-Patchoulene 514-51-2
    β-Patchoulene is a tricyclic sesquiterpene isolated from the oil of Pogostemon cablin (patchouli oil). β-Patchoulene can be used for the treatment of inflammatory diseases.
    β-Patchoulene
  • HY-N12381
    Spinasaponin E 2867584-02-7
    Spinasaponin E is a compound and can be used for inflammatory disease research.
    Spinasaponin E
  • HY-N12396
    Cyclosporin U 108027-45-8
    Cyclosporin U (SMP0V32C6L) is an cytostatic agent that plays an important role in preventing rejection of transplanted organs.
    Cyclosporin U
  • HY-N12399
    Aplithianines A 3027425-38-0
    Aplithianines A is a potent inhibitor against J-PKA with an IC50 of 1 μM , and inhibits wild-type PKA with an IC50 of 84 nM. Aplithianines A inhibits J-PKAcα catalytic activity by competitively binding to the ATP pocket.
    Aplithianines A
Cat. No. Product Name / Synonyms Application Reactivity