2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0889R
    Ginkgetin (Standard) 481-46-9
    Ginkgetin (Standard) is the analytical standard of Ginkgetin. This product is intended for research and analytical applications. Ginkgetin, a biflavone, is isolated from Ginkgo biloba leaves. Ginkgetin exhibit anti-tumor, anti-inflammatory, neuroprotective, anti-fungal activities. Ginkgetin is also a potent inhibitor of Wnt signaling, with an IC50 of 5.92 μΜ.
    Ginkgetin (Standard)
  • HY-N0893S
    Tetrahydrocurcumin-d6 1794898-13-7
    Tetrahydrocurcumin-d6 is a deuterium labeled Tetrahydrocurcumin. Tetrahydrocurcumin is a Curcuminoid which displays inhibitory activity for CYP2C9 and CYP3A4[1].
    Tetrahydrocurcumin-d6
  • HY-N0894A
    (3R,5R)-Octahydrocurcumin 408324-14-1
    (3R,5R)-Octahydrocurcumin (Compound 7) is gut microbial metabolite of Curcumin (HY-N0005). (3R,5R)-Octahydrocurcumin exhibits neuroprotective efficacy against Aβ25-35-induced cell damage in SH-SY5Y, and anti-inflammatory activity against LPS-stimulated mouse microglial BV-2.
    (3R,5R)-Octahydrocurcumin
  • HY-N0904R
    Ginsenoside C-K (Standard) 39262-14-1
    Ginsenoside C-K (Standard) is the analytical standard of Ginsenoside C-K. This product is intended for research and analytical applications. Ginsenoside C-K, a bacterial metabolite of G-Rb1, exhibits anti-inflammatory effects by reducing iNOS and COX-2. Ginsenoside C-K exhibits an inhibition against the activity of CYP2C9 and CYP2A6 in human liver microsomes with IC50s of 32.0±3.6 μM and 63.6±4.2 μM, respectively.
    Ginsenoside C-K (Standard)
  • HY-N0908R
    Ginsenoside Rg5 (Standard) 186763-78-0
    Ginsenoside Rg5 (Standard) is the analytical standard of Ginsenoside Rg5. This product is intended for research and analytical applications. Ginsenoside Rg5 is the main component of Red ginseng and IGF-1R agonist. Ginsenoside Rg5 compets for the binding site of IGF-1R and blocks the binding of IGF-1 to IGF-1R (IC50 about 90 nM). Ginsenoside Rg5 also inhibits the mRNA expression of COX-2 via suppression of the DNA binding activities of NF-κB p65.
    Ginsenoside Rg5 (Standard)
  • HY-N0915R
    Melittoside (Standard) 19467-03-9
    Melittoside (Standard) is the analytical standard of Melittoside. This product is intended for research and analytical applications.
    Melittoside (Standard)
  • HY-N0924B
    (-)-Stylopine 84-39-9
    (-)-Stylopine ((S)-Tetrahydrocoptisine) is an enantiomer of Stylopine (HY-N0924). Stylopine is a major alkaloid component of the leaf of Chelidonium majus.
    (-)-Stylopine
  • HY-N0947R
    (-)-Anomalin (Standard) 4970-26-7
    (-)-Anomalin (Standard) is the analytical standard of (-)-Anomalin. This product is intended for research and analytical applications. (-)-Anomalin ((-)-Praeruptorin B) is a coumarin derivative isolated from the root of Angelica anomala.
    (-)-Anomalin (Standard)
  • HY-N0948A
    (+)-Rhododendrol 59092-94-3
    (+)-Rhododendrol ((S)-(+)-Rhododendrol) is an anti-inflammatory agent that can suppress NO production.
    (+)-Rhododendrol
  • HY-N10009
    Cudraflavone B 19275-49-1
    Cudraflavone B is a prenylated flavonoid with anti-inflammatory and anti-tumor properties. Cudraflavone B is also a dual inhibitor of COX-1 and COX-2. Cudraflavone B blocks the translocation of nuclear factor κB (NF-κB) from the cytoplasm to the nucleus in macrophages. Thus, Cudraflavone B inhibits tumor necrosis factor α (TNFα) gene expression and secretion. Cudraflavone B also triggers the mitochondrial apoptotic pathway, activates NF-κB, the MAPK p38, and ERK, and induced the expression of SIRT1. Thus Cudraflavone B inhibits the growth of human oral squamous cell carcinoma cells.
    Cudraflavone B
  • HY-N10017
    Lucidone F 1446750-73-7
    Lucidone F is a nortriterpenoid analogue which is derivated from Ganoderma resinaceum. Lucidone F is promising for research of immune-regulation, hyperglycemia and liver disease.
    Lucidone F
  • HY-N10020
    Patulitrin 19833-25-1
    Patulitrin has scavenging effect in the DPPH radical. Patulitrin inhibits soybean lipoxygenase. Patulitrin also has antihypertensive effect. Patulitrin is an antioxidant flavonoid that can be isolated from Anthemis tinctoria.
    Patulitrin
  • HY-N10023
    Physalin O 120849-18-5
    Physalin O is a physalin that can be isolated from Physalis angulata. Physalin O shows cytotoxicity to Hep G2 and MCF-7 cancer cells with IC50 values of 31.1 and 11.4 µM, respectively. Physalin O inhibits the production of nitric oxide (NO) and shows anti-inflammatory activities.
    Physalin O
  • HY-N10059
    Quebecol 1360605-46-4
    Quebecol is a nutraceutical agent against periodontitis.
    Quebecol
  • HY-N10066
    Anti-inflammatory agent 5
    Anti-inflammatory agent 5 displays potent inhibition of NO generation in lipopolysaccharide-induced BV-2 microglial cells.
    Anti-inflammatory agent 5
  • HY-N10081
    Leucinostatin D 108426-90-0
    Leucinostatin D is a peptide antibiotic from Paecilomyces marquandii. Leucinostatin D shows biological activity against Gram-positive bacteria and several fungi.
    Leucinostatin D
  • HY-N10084
    Cordifolioside A 155179-20-7
    Cordifolioside A is a natural phenyl propanoid glycoside with immunomodulatory activity.
    Cordifolioside A
  • HY-N10092
    Saucerneol 88497-86-3
    Saucerneol is a lignans that can be isolated from Saururus chinensis. Saucerneol inhibits LPS-induced or Con A-induced lymphocytes proliferation. Saucerneol inhibits mixed lymphocyte response. Saucerneol also inhibits mitogens-induced cytokines secretion.
    Saucerneol
  • HY-N10106
    Dihydromyristicin 52811-28-6
    Dihydromyristicin, a plant flavonoid, has potent anti-inflammatory properties. Dihydromyristicin reduces endotoxic inflammation via repressing ROS-mediated activation of PI3K/Akt/NF-κB signaling pathways.
    Dihydromyristicin
  • HY-N10108
    Protosappanin A dimethyl acetal 868405-37-2
    Protosappanin A dimethyl acetal is a homoisoflavonoid. Protosappanin A dimethyl acetal can be isolated from Caesalpinia sappan. Protosappanin A dimethyl acetal is also a competive inhibitor with significant xanthine oxidase inhibitory activity (IC50=50.7 μM).
    Protosappanin A dimethyl acetal
Cat. No. Product Name / Synonyms Application Reactivity