2. Endocrinology

Endocrinology

Endocrinology

Related Products

PDF 21.44 MB

Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-13604R
    Cyproterone acetate (Standard) 427-51-0 98%
    Cyproterone acetate (Standard) is the analytical standard of Cyproterone acetate. This product is intended for research and analytical applications. Cyproterone acetate is an anti-androgen (IC50=7.1 nM) and progestogen synthetic steroid. Cyproterone acetate has affinity with progesteron and with glucocorticoidal receptors.
    Cyproterone acetate (Standard)
  • HY-13673S
    Goserelin-d10 98%
    Goserelin-d10 (ICI 118630-d10) is deuterium labeled Goserelin. Goserelin (ICI 118630), a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH), functions as a GnRH agonist. Goserelin can be used for the research of breast cancer, epithelial ovarian cancer and prostate cancer.
    Goserelin-d10
  • HY-136800
    Posatirelin 78664-73-0 98%
    Posatirelin, a TRH analog, increases monoamine metabolites in the cerebral cortex, nucleus accumbens, and striatum, and possibly exerts CNS activating effects through a modification of several neurotransmitter systems.
    Posatirelin
  • HY-13702R
    Nilutamide (Standard) 63612-50-0
    Nilutamide (Standard) is the analytical standard of Nilutamide. This product is intended for research and analytical applications. Nilutamide (Nilandron) is an orally active nonsteroidal androgen receptor antagonist with affinity for androgen receptors but not for progestogen, estrogen or glucocorticoid receptors. Nilutamide can be used to research prostate cancer. Nilutamide also has antischistosomal properties.
    Nilutamide (Standard)
  • HY-137043
    9-Keto Travoprost 1219032-18-4 98%
    9-Keto Travoprost is a derivative of Fluprostenol (HY-108560). 9-Keto Travoprost is an EP receptor agonist. 9-Keto Travoprost can be used in endocrine-related research.
    9-Keto Travoprost
  • HY-137089
    Azacosterol dihydrochloride 1249-84-9 98%
    Azacosterol (SC-12937) dihydrochloride is a chemosterilant which in-hibits reproduction in the pigeon. Azacosterol (SC-12937) dihydrochloride exerts its inhibitory effect through the blocking of the synthesis of cholesterol, thought to be a vital component in the formation of egg yolks.
    Azacosterol dihydrochloride
  • HY-13715S
    (Rac)-Norepinephrine-d3 formate 98%
    (Rac)-Norepinephrine-d3 (formate) is deuterium labeled Norepinephrine. Norepinephrine (Levarterenol; L-Noradrenaline) is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors.
    (Rac)-Norepinephrine-d3 formate
  • HY-137868
    Decanoyl coenzyme A 1264-57-9 99.9%
    Decanoyl coenzyme A (Decanoyl CoA) is a primer for the fatty acid elongation system in Mycobacterium smegmat.
    Decanoyl coenzyme A
  • HY-137919
    Fluticasone 17β-carboxylic acid 28416-82-2 98%
    Fluticasone 17β-carboxylic acid is an intermediate in the synthesis of the glucocorticosteroid Fluticasone propionate (HY-B0154).
    Fluticasone 17β-carboxylic acid
  • HY-137944
    5α-Dihydro levonorgestrel 78088-19-4 98%
    5α-Dihydro levonorgestrel is a metabolite of the synthetic progestin Levonorgestrel (HY-B0257).
    5α-Dihydro levonorgestrel
  • HY-137983
    3-O-Acetylbetulin 27570-20-3 98%
    3-O-Acetylbetulin is a derivative of Betulin (HY-N0083), a sterol regulatory element-binding protein (SREBP) inhibitor. 3-O-Acetylbetulin can be utilized in synthesis of other betulin derivatives.
    3-O-Acetylbetulin
  • HY-14111R
    GSK189254A (Standard) 720690-73-3
    GSK189254A (Standard) is the analytical standard of GSK189254A. This product is intended for research and analytical applications. GSK189254A (GSK189254 free base) is a novel, potent and selective histamine H3 receptor antagonist with pKi values of 9.59-9.90 and 8.51-9.17 for human and rat H3, respectively.
    GSK189254A (Standard)
  • HY-14127R
    R121919 (Standard) 195055-03-9
    R121919 (Standard) is the analytical standard of R121919. This product is intended for research and analytical applications. R121919 (NBI30775) is a potent and selective CRF1R antagonist with a Ki of 2 to 5 nM. R121919 has antidepressant and anxiolytic effects. R121919 alleviates defensive withdrawal in rats.
    R121919 (Standard)
  • HY-14185R
    Lixivaptan (Standard) 168079-32-1
    Lixivaptan (Standard) is the analytical standard of Lixivaptan. This product is intended for research and analytical applications. Lixivaptan (VPA-985, WAY-VPA 985) is an orally active and selective vasopressin receptor V2 antagonist, with IC50 values of 1.2 and 2.3 nM for human and rat V2, respectively.
    Lixivaptan (Standard)
  • HY-14247R
    Fadrozole hydrochloride (Standard) 102676-31-3
    Fadrozole (hydrochloride) (Standard) is the analytical standard of Fadrozole (hydrochloride). This product is intended for research and analytical applications. Fadrozole hydrochloride (CGS 16949A) is a potent, selective and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM.
    Fadrozole hydrochloride (Standard)
  • HY-14270R
    Lodoxamide (Standard) 53882-12-5
    Lodoxamide (Standard) is the analytical standard of Lodoxamide. This product is intended for research and analytical applications. Lodoxamide (U-42585E free acid) is an antiallergic compound acting as a mast-cell stabilizer for the treatment of asthma and allergic conjunctivitis.
    Lodoxamide (Standard)
  • HY-14281R
    Trilostane (Standard) 13647-35-3
    Trilostane (Standard) is the analytical standard of Trilostane. This product is intended for research and analytical applications. Trilostane (Win 24540) is a competitive and orally active 3-β-hydroxysteroiddehydrogenase (3β-HSD) inhibitor. Trilostane is a synthetic nonhormonal steroid. Trilostane can be used for the research of breast cancer and prostate cancer.
    Trilostane (Standard)
  • HY-14299R
    Indacaterol (Standard) 312753-06-3 98%
    Indacaterol (Standard) is the analytical standard of Indacaterol. This product is intended for research and analytical applications. Indacaterol is an orally active ultra-long-acting β2 adrenergic receptor (ADRB2) agonist. Indacaterol inhibits NF-κB activity in a β-arrestin2-dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol can also be used in cardiovascular disease research.
    Indacaterol (Standard)
  • HY-14302R
    Salmeterol (Standard) 89365-50-4
    Salmeterol (Standard) is the analytical standard of Salmeterol. This product is intended for research and analytical applications. Salmeterol (GR33343X) is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively.
    Salmeterol (Standard)
  • HY-14369R
    Elagolix sodium (Standard) 832720-36-2
    Elagolix sodium (Standard) is the analytical standard of Elagolix sodium. This product is intended for research and analytical applications. Elagolix sodium is a human GnRH receptor (GnRHR) antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively.
    Elagolix sodium (Standard)
Cat. No. Product Name / Synonyms Application Reactivity