2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (7658):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W742417
    Tazarotenic acid-d8
    Tazarotenic acid-d8 (AGN 190299-d8) is the deuterium labeled Tazarotenic acid (HY-101108). Tazarotenic acid is the metabolite of Tazarotene (HY-15388).
    Tazarotenic acid-d<sub>8</sub>
  • HY-119708S
    Ensifentrine-d6
    Ensifentrine-d6 (RPL-554-d6) is deuterium labeled Ensifentrine. Ensifentrine (RPL-554) is an inhaled first-in-class dual inhibitor of phosphodiesterase 3 (PDE3) and PDE4 with IC50s of 0.4 nM and 1479 nM, respectively. Ensifentrine has bronchoprotective and anti-inflammatory activities. Ensifentrine can be used for chronic obstructive pulmonary disease (COPD) research.
    Ensifentrine-d<sub>6</sub>
  • HY-W759629
    Selpercatinib-d3
    Selpercatinib-d3 (LOXO-292-d3) is deuterium labeled Selpercatinib. Selpercatinib (LOXO-292) is a potent, selective RET kinase inhibitor with IC50 values of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M), and RET (G810R), respectively. Selpercatinib has anticancer activity.
    Selpercatinib-d<sub>3</sub>
  • HY-W778064
    L-threo-Droxidopa-13C2
    L-threo-Droxidopa-13C2,15N is 13C- and 15N-labeled L-threo-Droxidopa.
    L-threo-Droxidopa-<sup>13</sup>C<sub>2</sub>
  • HY-P6425S
    LCADMEDV-Arg(13C6,15N4) TFA
    LCADMEDV-Arg(13C6, 15N4) TFA is a peptide containing 13C6 and 15N4 labeled Arg.
    LCADMEDV-Arg(<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N<sub>4</sub>) TFA
  • HY-17498S3
    Atenolol-13C6
    Atenolol-13C6 ((RS)-Atenolol-13C6) is 13C labeled Atenolol. Atenolol ((RS)-Atenolol) is a cardioselective β1-adrenergic receptor blocker, with a Ki of 697 nM at β1-adrenoceptor in guine pig left ventricle membrane. Atenolol can be used for the research of hypertension and angina pectoris.
    Atenolol-<sup>13</sup>C<sub>6</sub>
  • HY-17464S2
    Cilostazol-d2
    Cilostazol-d2 (OPC 13013-d2) is deuterium labeled Cilostazol. Cilostazol (OPC 13013) is a potent and selective inhibitor of phosphodiesterase (PDE) 3A, the isoform of PDE 3 in the cardiovascular system, with an IC50 of 0.2 μM.
    Cilostazol-d<sub>2</sub>
  • HY-131503S
    13-Methyltetradecanoic acid-d6
    13-Methyltetradecanoic acid-d6 is a deuterated labeled 13-Methyltetradecanoic acid. 13-Methyltetradecanoic acid (13-MTD), a saturated branched-chain fatty acid with potent anticancer effects. 13-Methyltetradecanoic acid induces apoptosis in many types of human cancer cells.
    13-Methyltetradecanoic acid-d<sub>6</sub>
  • HY-W654232
    L-Hydroxyproline-d4
    L-Hydroxyproline-d4 is deuterium labeled L-Hydroxyproline. L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.
    L-Hydroxyproline-d<sub>4</sub>
  • HY-17464S3
    Cilostazol-d6
    Cilostazol-d6 (OPC 13013-d6) is deuterium labeled Cilostazol. Cilostazol (OPC 13013) is a potent and selective inhibitor of phosphodiesterase (PDE) 3A, the isoform of PDE 3 in the cardiovascular system, with an IC50 of 0.2 μM.
    Cilostazol-d<sub>6</sub>
  • HY-W703549
    Aderbasib-d3
    Aderbasib-d3 (INCB007839-d3) is deuterium labeled Aderbasib. Aderbasib (INCB007839) is a potent, orally active and target specific low nanomolar hydroxamate-based inhibitor of ADAM10 and ADAM17. Aderbasib exhibits robust antineoplastic activity and can be used for cancer research, including diffuse large B-cell non-Hodgkin lymphoma, HER2+?breast cancer, gliomas, et al.
    Aderbasib-d<sub>3</sub>
  • HY-N6662S
    (+)-Longifolene-13,d2
    (+)-Longifolene-13C,d2 is the 13C- and deuterium labeled (+)-Longifolene (HY-N6662). (+)-Longifolene is a sesquiterpenoid and a metabolite in rabbits. (+)-Longifolen is converted to primary, secondary or tertiary alcohols in rabbits, among which the primary alcohol is predominant.
    (+)-Longifolene-<sup>13</sup>,d<sub>2</sub>
  • HY-W747703
    Hippuric acid-13C6
    Hippuric acid-13C6 (Benzoylglycine-13C6) is 13C labeled Hippuric acid. Hippuric Acid is an orally active metabolite. Hippuric Acid can be produced by intestinal microorganisms from the metabolism of polyphenols, benzoic acid. Hippuric Acid decreases NRF2, MMP9 and leads to ROS accumulation. Hippuric Acid activates TGFβ/SMAD signaling. Hippuric Acid improves hyperuricemia and colitis. Hippuric Acid can also be used in cardiovascular disease research. .
    Hippuric acid-<sup>13</sup>C<sub>6</sub>
  • HY-109583S
    4-Oxofenretinide-d4
    4-Oxofenretinide-d4 (4-Oxo-4-HPR-d4) is deuterium labeled 4-Oxofenretinide. 4-Oxofenretinide (4-Oxo-4-HPR) is a metabolite of Fenretinide (HY-15373). 4-Oxofenretinide induces cell growth inhibition in ovarian, breast, and neuroblastoma tumor cell lines. 4-Oxofenretinide causes a marked accumulation of cells in G2-M. 4-Oxofenretinide induces cancer cell apoptosis through caspase-9.
    4-Oxofenretinide-d<sub>4</sub>
  • HY-15414S1
    Vortioxetine-d6
    Vortioxetine-d6 (Lu AA 21004-d6) is the deuterium labeled Vortioxetine (HY-B1490A). Vortioxetine (Lu AA 21004) is an antagonist of 5-HT3A and 5-HT7 receptors (Ki: 3.7 nM, 19 nM) and an inhibitor of serotonin transporter (SERT) (Ki: 1.6 nM), as well as a 5-HT1A agonist and a partial agonist of 5-HT1B (Ki: 15 nM, 33 nM).
    Vortioxetine-d<sub>6</sub>
  • HY-W709575
    Spermidine-d6 trihydrochloride
    		≥98.0%
    Spermidine-d6 trihydrochloride is the deuterium labeled Spermidine-d6 (trihydrochloride) (HY-W709575).
    Spermidine-d<sub>6</sub> trihydrochloride
  • HY-113096S
    Prostaglandin D1-d4
    Prostaglandin D1-d4 (PGD1-d4) is deuterium labeled Prostaglandin D1. Prostaglandin D1 is a prostanoid which causes contractile and relaxant on isolated human pial arteries, it is also an inhibitor of ADP-induced platelet aggregation with an IC50 value of 320 ng/ml. Prostaglandin D1 can be used for metabolic research.
    Prostaglandin D1-d<sub>4</sub>
  • HY-W712501
    Methyl-d3 2-hydroxybenzoate
    Methyl-d3 2-hydroxybenzoate is deuterated labeled Methyl 2-hydroxybenzoate.
    Methyl-d3 2-hydroxybenzoate
  • HY-132559S
    PD-166285-d4
    PD-166285-d4 is the deuterium labeled PD-166285[1].
    PD-166285-d<sub>4</sub>
  • HY-W012531S2
    2-Hydroxycinnamic acid-d4
    2-Hydroxycinnamic acid-d4 is deuterium labeled 2-Hydroxycinnamic acid. 2-Hydroxycinnamic acid is a phenolic acid with antimicrobial and antioxidant properties. 2-Hydroxycinnamic acid has antimicrobial activity against Staphylococcus aureus and is not susceptible to drug resistance. 2-Hydroxycinnamic acid shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC50 of 0.3 mM. In addition, 2-Hydroxycinnamic acid has neuroprotective and antitumor activity.
    2-Hydroxycinnamic acid-d<sub>4</sub>