2. Signaling Pathways
  3. GPCR/G Protein
  4. GHSR
  5. GHSR Isoform
  6. GHSR Agonist

GHSR Agonist

GHSR Agonists (27):

Cat. No. Product Name Effect Purity
  • HY-14820
    Macimorelin
    		Agonist
    Macimorelin (EP-1572), a GH secretagogue, is an orally active GHSR agonist. Macimorelin stimulates GH release. Macimorelin can be used in the research of adult growth hormone deficiency (AGHD), and Cancer anorexia-cachexia syndrome (CACS).
  • HY-14495B
    BMS-604992 dihydrochloride
    		Agonist
    BMS-604992 (EX-1314) dihydrochloride is a selective, orally active small-molecule growth hormone secretagogue receptor (GHSR) agonist. BMS-604992 dihydrochloride demonstrates high-affinity binding (ki=2.3 nM) and potent functional activity (EC50=0.4 nM). BMS-604992 dihydrochloride can stimulate food intake in rodents.
  • HY-P4405
    (D-Ala2)-GRF (1-29) amide (human)
    		Agonist
    (D-Ala2)-GRF (1-29) amide (human) is a superagonist of GRF, exhibiting extremely high GH-releasing activity about 50 times that of GRF (1-29) in both pigs and rats.
  • HY-14734R
    Anamorelin (Standard)
    		Agonist
    Anamorelin (Standard) is the analytical standard of Anamorelin. This product is intended for research and analytical applications. Anamorelin (RC-1291) is a potent ghrelin receptor agonist with EC50 value of 0.74 nM in the FLIPR assay.
  • HY-10957A
    L-692429 hydrochloride
    		Agonist
    L-692429 (MK-0751) hydrochloride is a benzolactam derivative and a nonpeptidyl growth hormone secretagogue (GHS) agonist. L-692429 hydrochloride binds to G protein-coupled receptor with a Ki of 63 nM.
  • HY-111232
    GSK894281
    		Agonist
    GSK894281 is an orally active and highly potent ghrelin receptor full agonist with a pEC50 of <4.9 at the human motilin receptor. GSK894281 effectively enters the CNS. GSK894281 has the potential for constipation or to assist in emptying the colon prior to colonoscopy or colon surgery research.
  • HY-14734B
    Anamorelin Fumarate
    		Agonist
    Anamorelin Fumarate is a novel ghrelin receptor agonist with EC50 value of 0.74 nM in the FLIPR assay.