2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N3138
    Ombuoside 20188-85-6 99.68%
    Ombuoside is a glycoside ombuoside isolated from Gynostemma pentaphyllum.Ombuoside has antimicrobial activity against several strains of gram-positive and gram-negative bacteria and the yeast Candida albicans. Ombuoside has antioxidant effects by scavenging free radicals and ROS.
    Ombuoside
  • HY-N3307
    (+)-Medioresinol 40957-99-1 98.88%
    (+)-Medioresinol is a furofuran type lignan with antifungal, antibacterial and lesishmanicidal activities. (+)-Medioresinol leads to intracellular ROS accumulation and mitochondria-mediated apoptotic cell death in Candida albicans. (+)-Medioresinol can reduce the cardiovascular disease risk.
    (+)-Medioresinol
  • HY-N3488
    Isodiospyrin 20175-84-2 99.77%
    Isodiospyrin, a natural dimeric naphthoquinone, is a human DNA topoisomerase I (Topoisomerase) inhibitor. Isodiospyrin can prevent both DNA relaxation and kinase activities of human topoisomerase I. Isodiospyrin shows anticancer, antibacterial and antifungal activities.
    Isodiospyrin
  • HY-N3651
    Curzerenone 20493-56-5 ≥98.0%
    Curzerenone is one of constituents of leaf essential oil extracted from L. pulcherrima. Shows slight inhibitory effective against E. coli.
    Curzerenone
  • HY-N4122
    Neodiosmin 38665-01-9 99.37%
    Neodiosmin is a flavone glycoside isolated from the leaves of Citrus aurantium.
    Neodiosmin
  • HY-N5124
    Meloside A 60767-80-8
    Meloside A (Isovitexin 2''-O-glucoside) is a phenylpropanoid isolated from barley with antioxidant activity. In barley, phenylpropanoids have been described as having protective properties against excess UV-B radiation and have been linked to resistance to pathogens.
    Meloside A
  • HY-N6005
    Methyl caffeate 3843-74-1 99.89%
    Methyl caffeate, an antimicrobial agent, shows moderate antimicrobial and prominent antimycobacterial activities. Methyl caffeate also exhibits α-glucosidase inhibition activity, oxidative stress inhibiting activity, anti-platelet activity, antiproliferative activity in cervix adenocarcinoma and anticancer activity in lung and leukmia cell lines.
    Methyl caffeate
  • HY-N6583
    Licoflavonol 60197-60-6 ≥99.0%
    Licoflavonol, a minor flavone from the roots of Glycyrrhiza uralensis, is an inhibitor of the Salmonella type III secretion system (T3SS).
    Licoflavonol
  • HY-N6661
    Verbenone 1196-01-6 99.27%
    Verbenone ((-)-Verbenone) is a natural terpene in leaves of the tree, Verbena officinalis. Verbenone has anti-aggregation pheromone and interrupts the attraction of bark beetles to their aggregation pheromones.
    Verbenone
  • HY-N6790
    Nonactin 6833-84-7 ≥99.0%
    Nonactin is a macrotetrolide antibiotic and mitochondrial uncoupler with antibacterial, insecticidal, and acaricidal activities. Nonactin acts as an ionophore for monovalent cations, including K+, and NH4+, and it can also inhibit the surface expression of endogenous HSP60. In addition, Nonactin can induce apoptosis in β-catenin mutant tumor cells and has anti-tumor activity.
    Nonactin
  • HY-N7123
    Sulfacetamide 144-80-9 99.81%
    Sulfacetamide (Sulphacetamide) is a sulfonamide antibiotic that can be used for the study of ocular infections. Sulfacetamide has antifungal and antibacterial activities.
    Sulfacetamide
  • HY-N8213
    Rapanone 573-40-0 99.20%
    Rapanone is a natural benzoquinone. Rapanone exhibits a broad spectrum of biological actions, including anti-tumor, antioxidant, anti-inflammatory, antibacterial and antiparasitic. Rapanone also is a potent and selective human synovial PLA2 inhibitor, with an IC50 of 2.6 μM.
    Rapanone
  • HY-N9362
    Emodinanthrone 491-60-1 98.08%
    Emodinanthrone, an anthraquinone, is a sprecursor of Emodin (HY-14393) with antibiotic activity. Emodinanthrone inhibits respiration-driven solute transport at micromolar concentrations in membrane vesicles of Escherichia coli.
    Emodinanthrone
  • HY-P1258
    PSI 158442-41-2
    PSI (Proteasome Inhibitor 1) is a potent proteasome inhibitor. PSI inhibits the proliferation of primary effusion lymphoma (PEL) cells. PSI has the potential for the research of Kaposi’s sarcoma-associated herpesvirus (KSHV) infection and KSHV-associated lymphomas.
    PSI
  • HY-P2315
    Human β-defensin-1 452274-53-2 99.33%
    Human β-defensin-1 (HβD-1) is a cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by all epithelial surfaces, but also by circulatory cells and cells of the reproductive tract. Human β-defensin-1 has antimicrobial activities against a broad-sperm bacteria.
    Human β-defensin-1
  • HY-P2822
    Phosphoglycerate kinase, yeast 9001-83-6
    Phosphoglycerate kinase, yeast (PGK), namely phosphoglycerate kinase, is a glycolytic enzyme commonly used in biochemical research. Phosphoglycerate kinase can catalyze the reversible transfer of phosphate groups from 1,3-bisphosphoglycerate (1,3-BPG) to ADP to generate 3-phosphoglycerate (3-PG) and ATP. At the same time, it can also participate in gluconeogenesis, catalyzing the opposite reaction to produce 1,3BPGA and ADP. Phosphoglycerate kinase is involved in energy metabolism, interaction with nucleic acid, tumor progression, cell death and virus replication and other related processes.
    Phosphoglycerate kinase, yeast
  • HY-P3914
    Cecropin A (1-7)-Melittin A (2-9) 157606-25-2 98.23%
    Cecropin A (1-7)-Melittin A (2-9) is an antimicrobial peptide with antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative aerobic bacteria, as well as antimalarial activity, without the adverse hemolytic properties of bee venom peptides.
    Cecropin A (1-7)-Melittin A (2-9)
  • HY-100176
    PF-4878691 532959-63-0 99.89%
    PF-4878691 (3M-852A) is an orally active TLR7 agonist. PF-4878691 has the innate immune response activity, antiviral efficacy against HCV, and can be used for the research of cancer.
    PF-4878691
  • HY-101479
    Iclaprim 192314-93-5 99.49%
    Iclaprim is a new selective bacterial Dihydrofolate inhibitor, which can inhibit the growth of S. aureus (MRSA) with an MIC90 of 0.06 μg/mL.
    Iclaprim
  • HY-10545A
    Taribavirin hydrochloride 40372-00-7 ≥98.0%
    Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin hydrochloride is a Ribavirin proagent, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia.
    Taribavirin hydrochloride
Cat. No. Product Name / Synonyms Application Reactivity