1. Gene
  2. GNPDA1 - glucosamine-6-phosphate deaminase 1 Gene

GNPDA1 - glucosamine-6-phosphate deaminase 1 Gene

Homo sapiens

Also known as GPI; HLN; GNP1; GNPI; GNPDA

Gene ID: 10007 | Gene type: protein coding

About GNPDA1

Cytogenetic location: 5q31.3 Genomic coordinates (GRCh38): 5:142,000,671-142,013,027 (from NCBI)

This gene has 13 transcripts (splice variants), 221 orthologues and 1 paralogue. Ubiquitous expression in kidney (RPKM 29.0), urinary bladder (RPKM 18.6) and 24 other tissues.


Glucosamine-6-phosphate deaminase (EC is an allosteric Enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium (Arreola et al., 2003 [PubMed 12965206]).[supplied by OMIM, Jan 2010]

GNPDA1 Products(1)

mRNA Protein Name
NM_005471.5 NP_005462.1 glucosamine-6-phosphate isomerase 1

GNPDA1 Protein Structure


Glucosamine_iso: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase (17 - 216)

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  • 289 a.a.
Protein Preferred Names Protein Names

glucosamine-6-phosphate isomerase 1


Orthologs Information

Species Symbol Source ID
Macaca mulatta GNPDA1 VGNC VGNC:73101
Rattus norvegicus GNPDA1 RGD RGD:1585624
Canis familiaris GNPDA1 VGNC VGNC:41331
Bos taurus GNPDA1 VGNC VGNC:29476
Felis catus GNPDA1 VGNC VGNC:62630
Mus musculus GNPDA1 MGD MGI:1347054