2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (7659):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-170007S
    5(Z),8(Z)-Tetradecadienoic Acid-d11
    5(Z),8(Z)-Tetradecadienoic Acid-d11 is deuterium labeled 5(Z),8(Z)-Tetradecadienoic Acid.
    5(Z),8(Z)-Tetradecadienoic Acid-d<sub>11</sub>
  • HY-W199117S
    1,1-Diethoxypropane-d10
    1,1-Diethoxypropane-d10 is a deuterated labeled 1,1-Diethoxypropane.
    1,1-Diethoxypropane-d<sub>10</sub>
  • HY-17395S1
    Terbinafine-d5 hydrochloride
    Terbinafine-d5 (TDT 067-d5) hydrochloride is deuterium-labeled Terbinafine hydrochloride (HY-17395).
    Terbinafine-d<sub>5</sub> hydrochloride
  • HY-167600AS
    18:0 PA-d70
    18:0 PA-d70 is deuterium labeled 18:0 PA0.
    18:0 PA-d<sub>70</sub>
  • HY-B1125S
    Glucosamine-13C6
    Glucosamine-13C6 (D-Glucosamine-13C6) is 13C labeled Glucosamine. Glucosamine (D-Glucosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes.
    Glucosamine-<sup>13</sup>C<sub>6</sub>
  • HY-B0122S
    Topiramate-13C6
    Topiramate-13C6 (McN 4853-13C6) is the 13C labeled isotope of Topiramate (HY-B0122). Topiramate (McN 4853) is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels, increases in potassium conductance, and inhibition of carbonic anhydrase.
    Topiramate-<sup>13</sup>C<sub>6</sub>
  • HY-W421778S
    1,4-Bis(methylthio)benzene-d6
    1,4-Bis(methylthio)benzene-d6 is the deuterium labeled 1,4-Bis(methylthio)benzene (HY-B1234).
    1,4-Bis(methylthio)benzene-d<sub>6</sub>
  • HY-13458S2
    Droxidopa-13C6
    Droxidopa-13C6 (L-DOPS-13C6) is 13C labeled Droxidopa. Droxidopa (L-DOPS; SM5688) is a potent, orally active norepinephrine precursor. Droxidopa increases standing blood pressure, ameliorates symptoms of orthostatic hypotension and improves standing ability. Droxidopa has the potential for the research of neurogenic orthostatic hypotension (nOH) and alternative ADHD (attention deficit hyperactivity disorder).
    Droxidopa-<sup>13</sup>C<sub>6</sub>
  • HY-10002S
    Calcitriol-13C3
    Calcitriol-13C3 is the 13C-labeled Calcitriol. Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.
    Calcitriol-<sup>13</sup>C<sub>3</sub>
  • HY-17637S2
    Lumateperone-d4
    Lumateperone-d4 (ITI-007-d4) is deuterium labeled Lumateperone. Lumateperone (ITI-007) is an orally active 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a dopamine D1 receptor modulator. Lumateperone has anticancer activity and can also be used for the study of schizophrenia and bipolar depression.
    Lumateperone-d<sub>4</sub>
  • HY-166872S
    N-Benzyl paroxetine-d6
    N-Benzyl paroxetine-d6 is the deuterium labeled N-Benzyl paroxetine.
    N-Benzyl paroxetine-d<sub>6</sub>
  • HY-173105S
    TPEEAHALSA(Pro-13C5,15N)TSR TFA
    TPEEAHALSA(Pro-13C5,15N)TSR TFA is the 13C- and 15N-labeled TPEEAHALSA(Pro)TSR TFA.
    TPEEAHALSA(Pro-<sup>13</sup>C<sub>5</sub>,<sup>15</sup>N)TSR TFA
  • HY-W654009
    Loxoprofen-d3
    Loxoprofen-d3 is deuterium labeled Loxoprofen. Loxoprofen is a non-steroidal, orally active anti-inflammatory agent with analgesic and anti-pyretic properties. Loxoprofen is a nonselective COX inhibitor with IC50s of 6.5 and 13.5 μM for COX-1 and COX-2, respectively. Loxoprofen can reduce atherosclerosis and shows antitumor activity.
    Loxoprofen-d<sub>3</sub>
  • HY-16069S
    Tucatinib-d6
    Tucatinib-d6 (Irbinitinib-d6) is deuterium labeled Tucatinib. Tucatinib (Irbinitinib) is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM.
    Tucatinib-d<sub>6</sub>
  • HY-Y0626S
    Acetohydrazide-d3
    Acetohydrazide-d3 (Ethanehydrazonic acid-d3) is deuterium labeled Acetohydrazide. Acethydrazide is an organic building that undergo catalytic hydrogenation to produce N′-methyl acethydrazide (MAH).
    Acetohydrazide-d<sub>3</sub>
  • HY-W012932S
    2,4-Dimethylthiazole-13C3
    2,4-Dimethylthiazole-13C3 is 13C labeled 2-Isopropyl-3-methoxypyrazine.
    2,4-Dimethylthiazole-<sup>13</sup>C<sub>3</sub>
  • HY-W703429S
    2,3,6,7-Tetrachloro-naphthalene-13C10
    2,3,6,7-Tetrachloro-naphthalene-13C10 is 13C labeled 2,3,6,7-Tetrachloronaphthalene.
    2,3,6,7-Tetrachloro-naphthalene-<sup>13</sup>C<sub>10</sub>
  • HY-N0368S1
    Linalool-13C3
    Linalool-13C3 is 13C labeled α-Hexylcinnamaldehyde (HY-W014118). α-Hexylcinnamaldehyde, a compound derived from Cinnamaldehyde. α-Hexylcinnamaldehyde has the potential antimutagenic and chemosensitizing properties. α-Hexylcinnamaldehyde is widely used as an ingredient in many personal care, and as an additive in food and the pharmaceutical industry.
    Linalool-<sup>13</sup>C<sub>3</sub>
  • HY-17000S
    Tolvaptan-d7
    Tolvaptan-d7 is the deuterium labeled Tolvaptan. Tolvaptan is a selective, competitive arginine vasopressin receptor 2 antagonist with an IC50 of 1.28μM for the inhibition of AVP-induced platelet aggregation[1][2].
    Tolvaptan-d<sub>7</sub>
  • HY-B1363S1
    Bendroflumethiazide-d7
    Bendroflumethiazide-d7 (Bendrofluazide-d7) is deuterium labeled Bendroflumethiazide (HY-B1363). Bendroflumethiazide (Bendrofluazide) is an orally available diuretic. Bendroflumethiazide inhibits the electroneutral sodium-chloride symporter located in the apical membrane of the early segment of the distal convoluted tubule and can effectively lower blood pressure. Bendroflumethiazide is used in the study of hypertension and edema. Bendroflumethiazide has an antidiuretic effect in diabetes insipidus.
    Bendroflumethiazide-d<sub>7</sub>