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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W027544
    MCA
    		98.87%
    MCA (7-Methoxycoumarin-4-acetic acid) is a Coumarin (HY-N0709) derivative. MCA quantitates platelet-activating factor (PAF) by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities.
    MCA
  • HY-D1044
    Rhodamine 101 chloride
    Rhodamine 101 chloride (Rhodamine 640 chloride) is a bright fluorescent dye with excitation and emission maxima of 565 and 595 nm, respectively.
    Rhodamine 101 chloride
  • HY-101937C
    (±)-ANAP hydrochloride
    (±)-ANAP hydrochloride is the unnatural amino acid analog of prodan, acts as a fluorescent probes, and enhances environmental sensitivity.
    (±)-ANAP hydrochloride
  • HY-D1042
    1,4-Dichloro 5-carboxytetramethylrhodamine
    		98.00%
    1,4-Dichloro 5-carboxytetramethylrhodamine is a fluorescence labeling agent (Ex=541 nm, Em=568 nm).
    1,4-Dichloro 5-carboxytetramethylrhodamine
  • HY-P4426A
    Lys-Pro-AMC diTFA
    Lys-Pro-AMC diTFA is a fluorogenic substrate for the detection and measurement of the activity of specific enzymes.
    Lys-Pro-AMC diTFA
  • HY-D1794
    Vari Fluor 405 SE
    		98.0%
    Vari Fluor 405 SE (VF 405 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=399 nm/421 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
    Vari Fluor 405 SE
  • HY-D1622
    Cyanine3 DBCO hexafluorophosphate
    Cyanine3 DBCO (Cy3-DBCO) hexafluorophosphate is a azide reactive probe, for imaging azide-labeled biomolecules via a copper-free "click-through" reaction.
    Cyanine3 DBCO hexafluorophosphate
  • HY-D1570
    BODIPY FL C12
    		99.79%
    BODIPYFL C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells. Maximum excitation/emission wavelength: 480/508 nm.
    BODIPY FL C12
  • HY-W035214
    Hydroxyisohexyl 3-cyclohexene carboxaldehyde
    Hydroxyisohexyl 3-cyclohexene carboxaldehyde is a hapten probe.
    Hydroxyisohexyl 3-cyclohexene carboxaldehyde
  • HY-110393
    CLR1501
    		98.62%
    CLR1501, a fluorescently labeled CLR1404 analog, is a cancer cell-selective fluorescence compound.
    CLR1501
  • HY-W019810
    3-(Dansylamino)phenylboronic acid
    		99.03%
    3-(Dansylamino)phenylboronic acid, a phenylboronic acid derivative, can be used for the glucose detection.
    3-(Dansylamino)phenylboronic acid
  • HY-D2000
    ATTO 488
    		99.00%
    ATTO 488 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 500/520 nm.
    ATTO 488
  • HY-52112
    BCDA
    		99.80%
    BCDA (5-bromo-4-chloroindoxyl acetate) is a chromogenic substrate of esterase used to potently detect the activity of esterase.
    BCDA
  • HY-138659
    Janelia Fluor® 646, Tetrazine
    Janelia Fluor 646, Tetrazine (JF646, Tetrazine) a red fluorescent dye that contains a tetrazine group. JF646, Tetrazine can be used in cellular imaging. Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Janelia Fluor? 646, Tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    Janelia Fluor® 646, Tetrazine
  • HY-P6027A
    H-D-CHA-Ala-Arg-pNA diacetate
    		99.83%
    H-D-CHA-Ala-Arg-pNA diacetate is the diacetate form of H-D-CHA-Ala-Arg-pNA (HY-P6027). H-D-CHA-Ala-Arg-pNA diacetate is a chromogenic substrate for the amidolytic assay.
    H-D-CHA-Ala-Arg-pNA diacetate
  • HY-D1080R
    EDANS (Standard)
    EDANS (1,5-EDANS) (Standard) is an analytical standard for EDANS. This product is intended for research and analytical applications. EDANS (1,5-EDANS) is a novel quenched fluorogenic substrate for the analysis of retroviral proteases by resonance energy transfer.
    EDANS (Standard)
  • HY-118562
    Dansylamide
    		99.28%
    Dansyl amide is a fluorescent dye that is used in biochemistry and chemistry to label substances with the fluorescent dansyl group.
    Dansylamide
  • HY-137100
    Cy 5 hydrazide
    Cy 5 hydrazide (Cyanine5 hydrazide) is a fluorescent dye for aldehydes and ketones. Cy 5 hydrazide can be used for labeling proteins.
    Cy 5 hydrazide
  • HY-D1372A
    Cyanine3 amine TFA
    		99.76%
    Cyanine3 amine (TFA), an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine (TFA) has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λex=555 nm, λem=570 nm).
    Cyanine3 amine TFA
  • HY-D1275
    CAY10731
    CAY10731 (compound 3) is a highly selective fluorescent probe for detection of hydrogen sulfide (H2S). CAY10731 is used to monitor exo- and endogenous H2S in both cancer and normal cells. CAY10731 is applied for imaging of H2S in living tissues at variable depths and in nematodes.
    CAY10731
Cat. No. Product Name / Synonyms Application Reactivity