2. Signaling Pathways
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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-145445
    BIOTIN-PEG11-SH
    		≥98.0%
    BIOTIN-PEG11-SH enables biotin labeling of protein.
    BIOTIN-PEG11-SH
  • HY-118907
    Methyl Orange
    		99.41%
    Methyl Orange is a soluble azo dye commonly used as an acid-base indicator and for staining cells and tissue sections, as well as for dyeing textiles. Methyl Orange appears red at a pH of 3.1 and changes to bright yellow as the pH increases to 4.4. Methyl Orange (500 mg/L) exhibits cytotoxicity and can cause DNA damage.
    Methyl Orange
  • HY-15630A
    Hoechst 33342 analog 2 trihydrochloride
    		98.02%
    Hoechst 33342 analog 2 trihydrochloride is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution.
    Hoechst 33342 analog 2 trihydrochloride
  • HY-110128
    Sulfidefluor 7-AM
    		≥99.0%
    Sulfidefluor 7-AM is a stable hydrogen sulphide (H2S) fluorescent probe. Sulfidefluor 7-AM is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Sulfidefluor 7-AM
  • HY-131010
    Flutax-2 (5/6-mixture)
    Flutax-2 (5/6-mixture) is an active fluorescent derivative of paclitaxel. Flutax-2 (5/6-mixture) binds to a polymerized α,β tubulin dimer. Excitation/emission wavelength: 496/524 nm. Paclitaxel, a diterpenoid secondary metabolite produced by Taxus species, can be used for the research of a variety of cancers.
    Flutax-2 (5/6-mixture)
  • HY-130022
    HKPerox-1
    		99.35%
    HKPerox-1 is a highly sensitive green fluorescent probe for the specific detection of H2O2 in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively.
    HKPerox-1
  • HY-D1732
    FITC-hyodeoxycholic acid
    		98.94%
    FITC-hyodeoxycholic acid is a hyodeoxycholic acid labeled with FITC, which can be used to study the mechanism of action of hyodeoxycholic acid.
    FITC-hyodeoxycholic acid
  • HY-113870
    6-NBDG
    		98.7%
    6-NBDG is a fluorescent glucose analogue, it can be used for fluorescence imaging and monitoring glucose transport and uptake. 6-NBDG can be used as a fluorescent probe for detecting macrophage-rich atherosclerotic plaques.
    6-NBDG
  • HY-D0936
    SPQ
    		99.52%
    SPQ is being used to examine and measure membrane chloride transport mechanisms.
    SPQ
  • HY-D1321A
    Cy 5 amine TFA
    		99.83%
    Cy 5 amine (Cyanine5 amine) TFA is a fluorescent dye. Cy 5 amine TFA can be used in the preparation of Cy5.5-labeled compound or polymers, which can be used for imaging cellular process and trafficking.
    Cy 5 amine TFA
  • HY-W040144
    Bromocresol green
    Bromocresol green is a pH-sensitive triphenylmethane dye commonly used for the determination of protein and albumin in serum. Bromocresol green is a bio-based dye with a yellow-green to blue-green color. Bromocresol green turns yellow (λmax=435 nm, protonated form) when placed in acidic solution (e.g. pH=4.15), and turns blue in basic solution (λmax=615 nm, deprotonated form). Bromocresol green is widely used as a pH indicator in the field of biochemical analysis. In addition, Bromocresol green is also used to detect the concentration of molecules such as creatinine, and to judge the viability of cells.
    Bromocresol green
  • HY-W040681
    7-Dimethylaminocoumarin-4-acetic acid
    		98.05%
    7-Dimethylaminocoumarin-4-acetic acid is a fluorescent probe.
    7-Dimethylaminocoumarin-4-acetic acid
  • HY-134435
    Z-Arg-AMC hydrochloride
    		99.2%
    Z-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin and papain. Z-Arg-AMC hydrochloride can be used to research activity of trypsin (Ex/Em=355/460 nm).
    Z-Arg-AMC hydrochloride
  • HY-W075353
    TPPS
    TPPS can be used as a non-cytotoxic probe for detecting tumor location.
    TPPS
  • HY-125815
    Reactive Blue 4
    Reactive Blue 4 is an anthraquinone dye, as a single colorimetric chemosensor for sequential determination of multiple analytes with different optical responses in aqueous media. Reactive Blue 4 is phytotoxic, cytotoxic and genotoxic. Reactive Blue 4 .
    Reactive Blue 4
  • HY-P4154
    Bevonescein
    		Inhibitor 99.97%
    Bevonescein (ALM-488) is a novel, intravenously-administrated fluorescein-conjugated peptide that binds nerve-associated connective tissue, labels peripheral nerves under real-time fluorescence imaging (FL) in living mice and human ex vivo nerve tissue. Bevonescein is a peptide-linked tracer which fluorescently labeled both intact and degenerated nerves.
    Bevonescein
  • HY-D2205
    Cy7 tyramide
    Cy7 tyramide, a red fluorescent dye, is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids.
    Cy7 tyramide
  • HY-P1883A
    Bacterial Sortase Substrate III, Abz/DNP TFA
    Bacterial Sortase Substrate III, Abz/DNP TFA is an internally quenched fluorescent peptide substrate. Staphylococcus aureus transpeptidase sortase A (SrtA) reacts with its native substrate Bacterial Sortase Substrate III, Abz/DNP, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Cleavage of this substrate can be monitored at Ex/Em=320 nm/420 nm.
    Bacterial Sortase Substrate III, Abz/DNP TFA
  • HY-D2083
    BODIPY 540 (purity 99%)
    		99.32%
    BODIPY 540 (purity>98%) is a BODIPY dye.BODIPY dye is a small molecule dye with strong UV absorption ability.Its fluorescence peak is relatively sharp, its quantum yield is high, and it is relatively insensitive to the polarity and pH value of the environment.BODIPY 540 (purity>98%) has a purity higher than 98% and is suitable for cell experiments.
    BODIPY 540 (purity 99%)
  • HY-D1266
    RB-OPD
    RB-OPD (NO-red) is a o-phenylenediamine (OPD)-locked rhodamine nitric oxide (NO) fluorescent probe with great sensitivity and selectivity (λex=550 nm, λem=590 nm).
    RB-OPD
Cat. No. Product Name / Synonyms Application Reactivity