Dipeptidyl Peptidase Inhibitor

Dipeptidyl Peptidase Inhibitors (156):

Cat. No.	Product Name	Effect	Purity

HY-P10809

VAMP	Inhibitor
VAMP, a tetrapeptide, is a competitive dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC₅₀ of 1.00 μM and a K_d of 6.89 μM. VAMP effectively targets the DPP-IV-GLP-1 axis and can be used for the study of type 2 diabetes.

HY-15408AR

Trelagliptin (succinate) (Standard)	Inhibitor
Trelagliptin (succinate) (Standard) is the analytical standard of Trelagliptin (succinate). This product is intended for research and analytical applications. Trelagliptin (SYR-472) succinate is a potent, orally active and highly selective DPP-4 inhibitor with an IC₅₀ of 4 nM. Trelagliptin succinate improves glycemic control in vivo and can be used for the study of type 2 diabetes mellitus (T2DM).

HY-13749CR

(S)-Sitagliptin (phosphate) (Standard)	Inhibitor
(S)-Sitagliptin (phosphate) (Standard) is the analytical standard of (S)-Sitagliptin (phosphate). This product is intended for research and analytical applications. (S)-Sitagliptin phosphate is the less active S-enantiomer of Sitagliptin phosphate. Sitagliptin phosphate (MK-0431 phosphate) is a potent inhibitor of DPP4 with an IC50 of 19 nM in Caco-2 cell extracts.

HY-14806R

Teneligliptin (Standard)	Inhibitor
Teneligliptin (Standard) is the analytical standard of Teneligliptin. This product is intended for research and analytical applications. Teneligliptin (MP-513) is a potent, orally available, competitive, and long-lasting DPP-4 inhibitor. Teneligliptin competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC₅₀s of approximately 1 nM.

HY-N8134

2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one	Inhibitor
2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one is a natural product found in the leaves and stem bark of M. glabra. 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one displays binding affinities with dipeptidyl peptidase-4 (DPP-4) and α-Amylase. 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one has potential antidiabetic activities.

HY-169724

RBx-0597	Inhibitor
RBx-0597 is a potent and selective DPP-IV inhibitor, demonstrating IC₅₀ values of 32, 31, and 39 nM against human, mouse, and rat plasma DPP-IV, respectively. RBx-0597 shows potential for type 2 diabetes research.

HY-170800

DPP-4-IN-15	Inhibitor
DPP-4-IN-15 (Compound 22) is a non-competitive inhibitor of dipeptidyl peptidase-4 (DPP-4) with an IC₅₀ of 8.24 μM.

HY-10285AR

Saxagliptin hydrate (Standard)	Inhibitor
Saxagliptin (hydrate) (Standard) is the analytical standard of Saxagliptin (hydrate). This product is intended for research and analytical applications. Saxagliptin hydrate (BMS-477118 hydrate) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) (Ki = 0.6-1.3 nM) inhibitor. Saxagliptin hydrate has the peotential for type 2 diabetes mellitus research.

HY-124163

Epostatin	Inhibitor
Epostatin is a competitive dipeptidyl peptidase II (DPP-II) inhibitor with an IC₅₀ of 0.96 μg/mL.

HY-14291R

Vildagliptin (Standard)	Inhibitor
Vildagliptin (Standard) is the analytical standard of Vildagliptin. This product is intended for research and analytical applications. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC₅₀ of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity.

HY-13749S3

Sitagliptin-d₆	Inhibitor
Sitagliptin-d₆ (MK-0431-d₆) is deuterium labeled Sitagliptin. Sitagliptin (MK-0431) is a potent and orally active inhibitor of DPP4 with an IC₅₀ of 19 nM in Caco-2 cell extracts.

HY-10285S1

(rel)-Saxagliptin-¹³C,d₂ TFA	Inhibitor
(rel)-Saxagliptin-¹³C,d₂ ((rel)-BMS-477118-¹³C,d₂) TFA is ¹³C-labeled Saxagliptin (HY-10285).

HY-N14989A

Fluostatin A sodium	Inhibitor
Fluostatin A sodium is a dipeptidyl peptidaseIII inhibitor with an IC₅₀ of 0.44 μg/mL. Fluostatin A can be extracted from Streptomyces sp. TA-3391.

HY-N14989

Fluostatin A	Inhibitor
Fluostatin A inhibits the ability of DPP-III, and with arginyl-arginine-2-naphthalene formamide as the substrate, the IC₅₀ is 0.44 μg/mL.

HY-14806S2

Teneligliptin-d₅	Inhibitor
Teneligliptin-d₅ (MP-513-d₅) is deuterium labeled Teneligliptin. Teneligliptin (MP-513) hydrobromide hydrate is an orally active and selective dipeptidyl peptidase 4 (DPP-4) inhibitor (IC₅₀s: 0.37 and 0.29 nM for the human and rat DPP-4, respectively). Teneligliptin hydrobromide hydrate improves blood glucose levels and can be used in researches related to type 2 diabetes mellitus.

HY-12733

AZD5248	Inhibitor
AZD5248 is a dipeptidyl peptidase 1 (DPP1) inhibitor that can be used for the research of chronic obstructive lung disease.

HY-13749S2

Sitagliptin-d₄	Inhibitor
Sitagliptin-d₄ (MK-0431-d₄) is deuterium labeled Sitagliptin. Sitagliptin (MK-0431) is a potent and orally active inhibitor of DPP4 with an IC₅₀ of 19 nM in Caco-2 cell extracts.

HY-N15181

Fluostatin B	Inhibitor
Fluostatin B is a dipeptidyl peptidase 3 (DPP-3) inhibitor with an IC₅₀ value of 24 µg/mL. Fluostatin B is a fluorenone, which is found in Streptomyces.

HY-16656

BMS-767778	Inhibitor
BMS-767778 is a selective DPP4 inhibitor, with a K_i of 0.9 nM.

HY-14877S1

Anagliptin-d₇	Inhibitor
Anagliptin-d₇ (SK-0403-d₇) is deuterium labeled Anagliptin. Anagliptin (SK-0403) is a highly selective, potent, orally active inhibitor of dipeptidyl peptidase 4 (DPP-4), with an IC₅₀ of 3.8 nM, and less selective at DPP-8 and DDP-9 with IC₅₀s of 68 nM and 60 nM, respectively.

Name
Email *

	Sorry, but the email address you supplied was invalid.