2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-137334
    Neuraminidase-IN-1 2379438-80-7 98.93%
    Neuraminidase-IN-1 is a neuraminidase inhibitor, with an IC50 of 0.21 μM. Neuraminidase-IN-1 has excellent activity against H1N1 influenza virus.
    Neuraminidase-IN-1
  • HY-137498
    EBOV/MARV-IN-1 2479465-67-1 99.14%
    EBOV/MARV-IN-1 is a potent inhibitor of Ebola virus (EBOV) and Marburg virus (MARV), with broad-spectrum activity (EC50=0.31, and 0.82 µM, respectively) and low cytotoxicity (SI>100) in HeLa cells.
    EBOV/MARV-IN-1
  • HY-138136
    Ticlatone 70-10-0 99.02%
    Ticlatone is an antifungal that can be used for the research of mycoses.
    Ticlatone
  • HY-138137
    Menaquinone 6 84-81-1 ≥98.0%
    Menaquinone 6 is a active product found in Wolinella succinogenes. Menaquinone 6 is a form of vitamin K2 (HY-109569) that has antimicrobial activity.
    Menaquinone 6
  • HY-138208
    Z-Phe-Tyr(tBu)-diazomethylketone 114014-15-2 ≥99.0%
    Z-Phe-Tyr(tBu)-diazomethylketone is a potent cathepsin L inhibitor. Z-Phe-Tyr(tBu)-diazomethylketone mediates reovirus disassembly. Z-Phe-Tyr(tBu)-diazomethylketone decreases viral detection.
    Z-Phe-Tyr(tBu)-diazomethylketone
  • HY-138546
    Fmoc-Tpi-OH 204322-23-6 99.24%
    Fmoc-Tpi-OH is a biologically active amino acid that can be used to synthesize antimicrobial peptide mimetics.
    Fmoc-Tpi-OH
  • HY-138585
    DMT-dG(dmf) Phosphoramidite 330628-04-1
    DMT-dG(dmf) Phosphoramidite is a phosphinamide monomer that can be used in the preparation of oligonucleotides
    DMT-dG(dmf) Phosphoramidite
  • HY-138589
    7-TFA-ap-7-Deaza-dG 666847-77-4 98.04%
    5'-O-TBDMS-dG is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid. 7-TFA-ap-7-Deaza-dG is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    7-TFA-ap-7-Deaza-dG
  • HY-138598
    5'-O-TBDMS-dG 51549-33-8 98.83%
    5'-O-TBDMS-dG is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.
    5'-O-TBDMS-dG
  • HY-138603
    5'-O-DMT-N4-Bz-2'-F-dC 146954-77-0 ≥98.0%
    5'-O-DMT-N4-Bz-2'-F-dC is a nucleoside with protective and modification effects.
    5'-O-DMT-N4-Bz-2'-F-dC
  • HY-138607
    5'-O-DMT-N2-DMF-dG 40094-22-2 99.09%
    5'-O-DMT-2'-O-TBDMS-rI is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.
    5'-O-DMT-N2-DMF-dG
  • HY-138614
    5'-O-DMT-2'-O-TBDMS-Ac-rC 121058-85-3 99.80%
    5'-O-DMT-2'-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.
    5'-O-DMT-2'-O-TBDMS-Ac-rC
  • HY-139442
    RdRP-IN-2 2863657-16-1 98.01%
    RdRP-IN-2 is a RNA dependent RNA polymerase (RdRp) inhibitor. RdRP-IN-2 significantly inhibits SARS-CoV-2 RdRp with an IC50 of 41.2 μM.RdRP-IN-2 also inhibits Feline coronavirus (FIPV) replication.
    RdRP-IN-2
  • HY-139743
    Aditoprime 56066-63-8 99.68%
    Aditoprime (Aditoprim), a selective bacterial dihydrofolate reductase (DHFR) inhibitor, inhibits the transformation of dihydrofolic acid to tetrahydrofolic acid. Aditoprime inhibits E.coli and L.casei DHFR with IC50 of 47 and 520 nM, respectively. Aditoprime has a broad antimicrobial spectrum, good antibacterial activity and excellent pharmacokinetics.
    Aditoprime
  • HY-139903
    Antifungal agent 18 2572713-30-3 98.08%
    Antifungal agent 18 is a novel antifungal agent for the research of fungal infection.
    Antifungal agent 18
  • HY-141841
    SARS-CoV-2-IN-7 2570461-66-2 99.40%
    SARS-CoV-2-IN-7 inhibits viral replication with a nanomolar IC50 value (844 nM) in SARS-CoV-2-infected Vero E6 cells.
    SARS-CoV-2-IN-7
  • HY-144513
    Stigmastan-3β-ol 19466-47-8 98.52%
    Stigmastan-3β-ol is a sterol that can be isolated from Tinospora sinensis and Ginkgo biloba L.. Stigmastan-3β-ol has antimicrobial activity.
    Stigmastan-3β-ol
  • HY-144646
    SP-471 2768010-39-3 99.79%
    SP-471 is a potent dengue virus (DENV) protease inhibitor with IC50 value of 18 μM. SP-471 inhibits both intermolecular and intramolecular protease processes of DENV.
    SP-471
  • HY-144701
    SABA1 690681-65-3 99.15%
    SABA1 possesses antibacterial properties against Pseudomonas aeruginosa and Escherichia coli, with an IC50 of 4.0 µM against E. coli ACC.
    SABA1
  • HY-145298
    Dicloromezotiaz 1263629-39-5 98.65%
    Dicloromezotiaz is a potent insecticide acting on nicotinic acetylcholine receptors (nAChRs). Dicloromezotiaz can be used to control a broad range of lepidoptera.
    Dicloromezotiaz
Cat. No. Product Name / Synonyms Application Reactivity