2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-135416A
    Streptolysin O (≥1000000 units/mg) 98072-47-0
    Streptolysin O (≥1000000 units/mg) is a ≥1000000 units/mg Streptolysin O (HY-135416). Streptolysin O, a group A streptococcal toxin, is a well-characterized oxygen-labile prototype of a cholesterol-binding bacterial exotoxin. Streptolysin O causes both lysis of cells and cardiotoxicity. Streptolysin O is widely used for the controlled permeabilization of cell membranes. Streptolysin O exists in two forms, a reduced active state and an oxidized reversibly inactive state.
    Streptolysin O (≥1000000 units/mg)
  • HY-14881AR
    Bedaquiline (fumarate) (Standard) 845533-86-0
    Bedaquiline (fumarate) (Standard) is the analytical standard of Bedaquiline (fumarate). This product is intended for research and analytical applications. Bedaquiline fumarate, a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.
    Bedaquiline (fumarate) (Standard)
  • HY-17373S1
    Posaconazole-d4 1133712-26-1 ≥99.0%
    Posaconazole-d4 is a deuterium-labeled form of Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity[1].
    Posaconazole-d4
  • HY-N0097S3
    Guanosine-15N5 99.60%
    Guanosine-15N5 is the 15N labeled Guanosine[1]. Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity[2].
    Guanosine-15N5
  • HY-U00124B
    Tromantadine hydrochloride 41544-24-5 ≥98.0%
    Tromantadine hydrochloride, an Amantadine derivative with antiherpetic activity, inhibits herpes simplex virus type 1 (HSV-1) and HSV-2 replication.
    Tromantadine hydrochloride
  • HY-W003561
    DHFR-IN-3 137553-43-6 99.48%
    DHFR-IN-3 is a dihydrofolate reductase (DHFR) inhibitor with the IC50 values of 19 μM and 12 μM in rat liver and P. carinii DHFR, respectively.
    DHFR-IN-3
  • HY-W005186
    6-Bromocoumarin 19063-55-9
    6-Bromocoumarin (compound 34) is a potential anti-bacterial agent, with no inhibition against 17β-HSD1. 6-Bromocoumarin exhibtis affinity for α and β estrogen receptors.
    6-Bromocoumarin
  • HY-W008216
    HMMNI 936-05-0 99.91%
    HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole (HY-B1244). Dimetridazole is a nitroimidazole class drug that combats protozoan infections.
    HMMNI
  • HY-W008833
    3-Aminobutanoic acid 541-48-0 ≥98.0%
    3-Aminobutanoic acid is a β-amino acid. 3-Aminobutanoic acid can protect plant against a challenge infection with P. infestans. 3-Aminobutanoic acid has various levels of susceptibility for the pathogen.
    3-Aminobutanoic acid
  • HY-W010937
    1-Butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide 174899-83-3 ≥98.0%
    1-Butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide (compound 8) is an HIV-1 integrase inhibitor that effectively inhibits both the 3'-processing (3'-P) and strand transfer (ST) steps of the integration reaction. 1-Butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide can be utilized in HIV-1 research.
    1-Butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide
  • HY-W011733
    Tulobuterol hydrochloride 56776-01-3 99.66%
    Tulobuterol hydrochloride (C-78) is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol hydrochloride is also a sympathomimetic agent used as a transdermal patch, increases normal diaphragm muscle strength. Tulobuterol hydrochloride inhibit rhinovirus replication and modulate airway inflammation.
    Tulobuterol hydrochloride
  • HY-W012738
    DL-Pyroglutamic acid 149-87-1 ≥98.0%
    DL-Pyroglutamic acid (CAE) as an inactivator of hepatitis B surface, inactivates vaccinia virus, herpes simplex virus, and influenza virus except poliovirus. DL-Pyroglutamic acid is also a possible inhibitor of GABA transaminase, increases GABA amount with antiepileptic action.
    DL-Pyroglutamic acid
  • HY-W016041
    2-Amino-2'-deoxyadenosine 4546-70-7 99.62%
    2-Amino-2'-deoxyadenosine is a deoxyribonucleoside used for the oligonucleotide synthesis.
    2-Amino-2'-deoxyadenosine
  • HY-W016969
    2-Undecanone 112-12-9 98.96%
    2-Undecanone is a volatile organic compound, which inhibits the DnaKJE-ClpB bichaperone dependent refolding of heat-inactivated bacterial luciferases. 2-Undecanone inhibits lung tumorigenesis.
    2-Undecanone
  • HY-W035409
    RPW-24 1001625-82-6 98.00%
    RPW-24 protects C. elegans from bacterial infection by stimulating the host immune response of the nematode. RPW-24 has antibacterial activity.
    RPW-24
  • HY-W041988
    Fmoc-Glu-OMe 145038-49-9 99.74%
    Fmoc-Glu-OMe, a glutamic acid derivative, shows antibacterial activity and gelation property in AgNO3 solution. Fmoc-Glu-OMe is a mouldable wound healing biomaterial.
    Fmoc-Glu-OMe
  • HY-W074930
    (S)-Tenofovir 147127-19-3 98.34%
    (S)-Tenofovir ((S)-GS 1278) is the less active S-enantiomer of Tenofovir. Tenofovir is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B (HBV).
    (S)-Tenofovir
  • HY-W115746
    Ethyl cellulose 9004-57-3
    Ethyl cellulose is a derivative of cellulose. Ethyl cellulose is a non-toxic, biodegradable polymer. Ethyl cellulose has unique properties such as oil gel formation, active ingredient delivery and film formation. Ethyl cellulose can be used as a pharmaceutical excipient, such as a coating agent, flavoring agent, tablet filler, etc. Ethyl cellulose can be used to prepare nanoparticles for active compound delivery.
    Ethyl cellulose
  • HY-W295873
    Cyclo(Phe-Gly) 5037-75-2 98.48%
    Cyclo(Phe-Gly) is a cyclodipeptides with antimicrobial and anticancer activities, isolated from broth culture of endophytic Streptomyces YIM 64018 associated with Paraboea sinensis.
    Cyclo(Phe-Gly)
  • HY-W395779
    EBOV-IN-1 1335113-30-8
    EBOV-IN-1 (com 3.47) is an adamantane dipeptide piperazine and an inhibitor of Ebola virus (EBOV). EBOV-IN-1 targets Niemann-Pick C1 (NPC1) and inhibits its binding to the EBOV glycoprotein (GP) that activates and mediates viral penetration into host cells, thereby inhibiting EBOV infection. EBOV-IN-1 inhibits pseudotyped EBOV infection with an IC50 of 13 nM.
    EBOV-IN-1
Cat. No. Product Name / Synonyms Application Reactivity