STX-100

Cat. No.: HY-P990667 Purity: 99.99%: Data Sheet
COA

SDS

FAQs
Technical Support

STX-100 is a humanized antibody expressed in HEK293 cells, targeting Integrin aVb6 (ITGAV & ITGB6). STX-100 has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145.12 kDa. The isotype control for STX-100 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

For research use only. We do not sell to patients.

CAS No. : 1439902-67-6

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Other Forms of STX-100:

STX-100 (Biotinylated) Get quote

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View All Integrin Isoform Specific Products:

View All Isoforms

αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

Biological Activity
Purity & Documentation
References
Customer Review

Description

Isotype

Human IgG1 kappa

Recommend Isotype Controls

Human IgG1 kappa, Isotype Control

Species Reactivity

Human

IC₅₀ & Target

Integrin aVb6

Clinical Trial

Gene ID

7040 [NCBI]

Accession

P01137

Application

ELISA, FACS, Functional assay

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

Molecular Weight

144.88 kDa

CAS No.

1439902-67-6

Appearance

Liquid

Color

Colorless to light yellow

Shipping

Shipping with dry ice.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Biological Activity

Immobilized Human Integrin alpha V beta 6 (ITGAV&ITGB6) can bind STX-100. The EC₅₀ for this effect is 131.5 ng/mL.

Purity & Documentation

Purity: 99.99%

Select Batch:

Data Sheet (256 KB) SDS (251 KB)

COA (231 KB) SDS-PAGE (81 KB) SEC-HPLC (208 KB)

Inhibitory Antibodies User Guide (602 KB)

References

[1]. Violette S, et al. Identification Of Biomarkers To Monitor The Activity Of STX-100, A Humanized Anti-±v²6 Antibody, In A Phase 2a Trial In Idiopathic Pulmonary Fibrosis[M]//B28. EMERGING BIOMARKERS OF COMPLEX LUNG DISEASES. American Thoracic Society, 2012: A2659-A2659.

STX-100 Related Classifications

Inflammation/Immunology

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

STX-1001439902-67-6STX100STX 100IntegrinHumanized AntibodyIntegrin aVb6 (ITGAV & ITGB6) AntibodyInhibitorinhibitorinhibit

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