2. Gene
  3. RNF26 - ring finger protein 26 Gene

RNF26 - ring finger protein 26 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 79102 | Gene type: protein coding

About RNF26

Cytogenetic location: 11q23.3 Genomic coordinates (GRCh38): 11:119,334,527-119,337,309 (from NCBI)

This gene has 1 transcript (splice variant) and 195 orthologues.

Summary

The protein encoded by this intronless gene contains a C3HC5 type of RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. The expression of this gene was found to be upregulated in Cancer cell lines derived from different types of Cancer. [provided by RefSeq, Jul 2008]

RNF26 Products(1)

mRNA Protein Name
NM_032015.5 NP_114404.1 E3 ubiquitin-protein ligase RNF26
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
21750715 GOA
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
25254379 GOA
Biological Process GO Annotation Evidence Reference Source
involved in endosome organization IDA
IDA: Inferred from direct assay
27368102 GOA
involved in negative regulation of defense response to virus IDA
IDA: Inferred from direct assay
25254379 GOA
involved in protein K11-linked ubiquitination IDA
IDA: Inferred from direct assay
25254379 GOA
involved in protein localization to perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
27368102 GOA
involved in protein ubiquitination IDA
IDA: Inferred from direct assay
27368102 GOA
involved in regulation of type I interferon production IDA
IDA: Inferred from direct assay
25254379 GOA
Cellular Component GO Annotation Evidence Reference Source
is active in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
33472082 GOA
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
25254379 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RNF26 Protein Structure

zf-C3HC4_3

zf-C3HC4_3: Zinc finger, C3HC4 type (RING finger) (377 - 426)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 433 a.a.
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase RNF26

ring finger protein with leucine zipper

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12085 RNF26 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus RNF26 RGD RGD:1305953
Mus musculus RNF26 MGD MGI:2388131
Canis familiaris RNF26 VGNC VGNC:45666
Bos taurus RNF26 VGNC VGNC:34061
Felis catus RNF26 VGNC VGNC:103745
Macaca mulatta RNF26 VGNC VGNC:101391