Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (3)

Isotope-Labeled Compounds Related Products (9899):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-B0640S

Epinastine-¹³C,d₃ hydrobromide
Epinastine-¹³C,d₃ (hydrobromide) is the ¹³C- and deuterium labeled Epinastine. Epinastine (WAL801) is an antihistamine and mast cell stabilizer. Epinastine is a potent, selective and orally-active histamine H1 receptor antagonist. Epinastine also inhibits IL-8 release and has an antiallergic action.

HY-B0241S1

Ipratropium-d₇ bromide
Ipratropium-d₇ (bromide)eis the deuterium labeled Ipratropium bromide. Ipratropium bromide (Sch 1000) is a muscarinic receptor antagonist, with binding IC₅₀ values of 2.9 nM, 2 nM, and 1.7 nM for M1, M2, and M3 receptors, respectively. Ipratropium bromide can be used in the research for COPD (chronic obstructive pulmonary disease) and asthma.

HY-150665S

N-Dansyl-d₆ 1,4-diaminobutane, 97% (CP)
N-Dansyl-d₆ 1,4-diaminobutane, 97% (CP) is the deuterium labeled N-Dansyl 1,4-diaminobutane, 97% (CP).

HY-15027S

5-Aminosalicylic Acid-d₃ hydrochloride		99.00%
5-Aminosalicylic Acid-d₃ (hydrochloride) is the deuterium labeled 5-Aminosalicylic Acid. 5-Aminosalicylic acid (Mesalamine) hydrochloride acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB.

HY-W771020

2-(Dodecyloxy)ethanol-d₂₅
2-(Dodecyloxy)ethanol-d₂5 (Ethylene glycol monododecyl ether-d₂5) is the deuterium labeled 2-(Dodecyloxy)ethanol (HY-W250300). 2-(Dodecyloxy)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-122272S2

Paroxetine-d₆-1
Paroxetine-d6-1 is a deuterated labeled Paroxetine. Paroxetine, a phenylpiperidine derivative, is a potent and selective serotonin reuptake inhibitor (SSRI). Paroxetine is a very weak inhibitor of norepinephrine (NE) uptake but it is still more potent at this site than the other SSRIs.

HY-77956S

Thyminose-¹³C
Thyminose-¹³C is the ¹³C labeled Thyminose. Thyminose is an endogenous metabolite.

HY-141907S

17β-Estradiol-¹³C₃		98.1%
17β-Estradiol-¹³C₃ is the ¹³C labeled 17β-Estradiol.

HY-W392933S5

Thymidine 5'-monophosphate-d₁₃ dilithium
Thymidine 5'-monophosphate-d₁₃ (Thymidine-5'-phosphate-d₁₃) dilithium is deuterium labeled Thymidine 5'-monophosphate (HY-W392933).

HY-17021S

Esomeprazole-d₃ sodium
Esomeprazole-d₃ (sodium) is the deuterium labeled Esomeprazole. Esomeprazole ((S)-Omeprazole) is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of the H+, K+-ATPase in gastric parietal cells. Esomeprazole has the potential for symptomatic gastroesophageal reflux disease research.

HY-10582S3

Flurbiprofen-d₄
Flurbiprofen-d₄ is deuterated labeled Flurbiprofen (HY-10582). Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities. Flurbiprofen is commonly used for the research of inflammatory diseases, including osteoarthritis and rheumatoid arthritis. Flurbiprofen is a non-selective cyclooxygenase (COX) inhibitor that can be used for the research of colorectal cancer.

HY-150628S

2-Oxobutanoic acid-¹³C,d₁ sodium hydrate
2-Oxobutanoic acid-¹³C,d₁ sodium hydrate is the deuterium and ¹³C labeled 2-Oxobutanoic acid sodium hydrate.

HY-W040268S1

1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-d₉
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-d₉ is deuterium labeled 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine. 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine is a phospholipid that is a major component of the lipid bilayer that surrounds cells and provides stability to the membrane.

HY-N0733S

Glucosamine-¹³C hydrochloride
Glucosamine-¹³C (hydrochloride) is the ¹³C labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a

HY-W015466S1

Acetylvaline-¹³C₂
Acetylvaline-13C2 is the ¹³C-labeled Acetylvaline (HY-W015466). Acetylvaline is an amino acid derivative belonging to the N-acetylated amino acid family. Acetylvaline can be detected in small quantities in the urine of healthy individuals but shows significantly abnormal excretion in the urine of patients with maple syrup urine disease (MSUD). Acetylvaline can be used to detect MSUD.

HY-B0154S

Fluticasone propionate-d₃
Fluticasone propionate-d₃ is the deuterium labeled Fluticasone propionate. Fluticasone propionate, a potent topical anti-inflammatory corticosteroid, is a selective glucocorticoid receptor agonist, with an absolute affinity (KD) of 0.5 nM. Fluticasone propionate shows little or no activity at other steroid receptors. Anti-viral activity.

HY-W027553S1

Ipidacrine-d₁₀
Ipidacrine-d₉ (NIK-247-d₉ (free base)) is the deuterium labeled Ipidacrine (HY-W027553). Ipidacrine is orally active and brain-penetrant AChE and BuChE inhibitors with IC₅₀ values of 1 μM and 1.9 μM, respectively, which is also a partial agonist of M2-cholinergic receptors and a reversible cholinesterase inhibitor. Ipidacrine has a stimulating effect on neuromuscular transmission and excitation along the nerve fibres with a moderately anti-pain effect. Ipidacrine is an aminopyridines and is structurally similar to Tacrine (HY-111338). Ipidacrine is effective in various amnesia models, improves erectile function and inhibits K+ and Na+-channels in the neuronal membrane in diabetic rats. Ipidacrine is promising for research of Alzheimer’s disease, ischaemic stroke, idiopathic neuropathy of the facial nerve, diabetes mellitus-induced erectile dysfunction and other deficits in central or peripheral cholinergic deseases.

HY-14648S1

Dexamethasone-d₅-1
Dexamethasone-d₅-1 is deuterium labeled Dexamethasone. Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.

HY-151912S

Picolinafen-d₄ (4-Fluorophenyl-d₄)
Picolinafen-d₄ (4-fluorophenyl-d₄) is the deuterium labeled Picolinafen.

HY-B0207AS1

Pyridostigmine-d₃ bromide
Pyridostigmine-d₃ (bromide) is the deuterium labeled Pyridostigmine bromide. Pyridostigmine bromide is a parasympathomimetic and a reversible cholinesterase inhibitor.

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